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Long-term testosterone therapy can cause hormone suppression, affect prostate and heart health, and alter physical characteristics, but does not increase prostate cancer risk and needs more research for full risk assessment.

People with diabetes or obesity should manage their conditions carefully as they have a higher risk of severe COVID-19.

The document suggests treating individuals with nonclassic congenital adrenal hyperplasia who show symptoms, especially those related to excess male hormones.

Multiple treatments work best for hair loss.

Spironolactone improved blood vessel function and cholesterol levels in non-obese women with PCOS.

Older age, higher BMI, and family history of diabetes increase the risk of gestational diabetes in pregnant women.

Dietary changes, including weight loss and a balanced diet, are important for managing PCOS, especially in overweight women.

Premature hair graying in young men is linked to family history, obesity, and smoking.

LLLT promotes hair growth and improves hair density safely in men and women.

Adult female acne requires a comprehensive treatment approach, including medical options and lifestyle changes, with attention to psychological well-being.

The French Endocrine Society suggests diagnosing PCOS with two of three signs, recommends lifestyle changes and clomiphene for treatment, and calls for more research on certain treatments and tests.

Insulin-lowering medications show promise for PCOS symptoms but can't be the main treatment yet due to limited long-term research.

Weight loss and metformin don't significantly change vaspin levels in women with PCOS.

The document suggests that clinical trials for PCOS should focus on meaningful primary outcomes like live birth rates, rather than less reliable surrogate markers.

The document concludes that treating PCOS requires a combination of drugs to manage reproductive and metabolic symptoms, with more research needed on combination therapies.

Sweat glands and hair follicles are structurally connected within a specific layer of skin fat.

The review found no clear link between vitamin D receptor gene variations and polycystic ovary syndrome.

Food deprivation increases MST enzyme in the brain, possibly affecting energy balance.

Women with androgen excess, especially those with PCOS, have a much higher risk of heart disease and stroke.

The document concludes that managing non-classical congenital adrenal hyperplasia in females requires personalized treatment, genetic counseling, and a team of specialists.

Diagnosing PCOS in teenagers is hard because its symptoms often look like normal puberty, and there's a need for better diagnosis methods and agreement on criteria.

Small changes in hormones can significantly impact health, showing the importance of sensitive testing for chemicals that disrupt hormones.

Testing for CAG repeat polymorphism in the androgen receptor gene is not currently recommended for managing hypogonadism.

People with Lichen Planus, especially with mucosal involvement, are more likely to have Metabolic Syndrome, which increases their risk for heart disease and diabetes.

Girls with PCOS during adolescence have a higher risk of developing type 2 diabetes, and early treatment can help manage this risk.

Mice with CBS deficiency are healthier on a low-methionine diet.

Hirsute women have lower type 2 17β-HSD enzyme levels, which improve with treatment.

Future osteoporosis treatments should focus on increasing bone growth, with many promising options available.

Adults with certain skin conditions may have higher levels of inflammation in their body.

Certain skin conditions can indicate insulin resistance and should prompt lifestyle changes and medical treatment to manage underlying health issues.