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Prostate cancer cells can make their own androgens to activate the androgen receptor, and treatments like abiraterone may increase this ability, suggesting new therapies should target the entire steroid-making pathway.

β-catenin is essential for stem cell activation and proliferation in hair follicles.

Super-enhancers controlled by pioneer factors like SOX9 are crucial for stem cell adaptability and identity.

Wnt signaling controls whether hair follicle stem cells stay inactive or regenerate hair.

Transplant success has improved with better immunosuppressive drugs and donor matching.

Sonic hedgehog signaling is crucial for hair growth and maintaining hair follicle identity.

Fibroblast growth factor receptor signaling controls cell development and repair, and its malfunction can cause disorders and cancer, but it also offers potential for targeted therapies.

Mesenchymal stem cells show potential for skin healing and anti-aging, but more research is needed for safe use, especially regarding stem cells from induced pluripotent sources.

LGR5 helps maintain corneal cell characteristics and prevents unwanted changes by controlling specific cell signaling pathways.

Hair follicle stem cells are a promising source for tissue repair and treating skin or hair diseases.

Using CRISPR for gene editing in the body is promising but needs better delivery methods to be more efficient and specific.

Tcf3 helps cells move and heal wounds by controlling lipocalin 2.

Keratins are important for skin cell health and their problems can cause diseases.

Brg1 is crucial for hair growth and skin repair by maintaining stem cells and promoting regeneration.

The document concludes that while there are promising methods to control CRISPR/Cas9 gene editing, more research is needed to overcome challenges related to safety and effectiveness for clinical use.

The drug enzalutamide may reduce the ability of the virus causing COVID-19 to enter lung cells.

The study suggests that motor neurons created from stem cells of patients with spinal and bulbar muscular atrophy show signs of the disease, including changes in protein levels and cell functions.

COVID-19 might affect male fertility, but more research is needed to understand the full impact.

Modified rat stem cells on a special scaffold improved blood vessel formation and wound healing in skin substitutes.

Hoxc genes control hair growth through Wnt signaling.

ΔNp63α helps control a protein that stops cancer cells from spreading.

Androgen receptor signaling causes early aging of cells important for hair growth by damaging their DNA.

Post-finasteride syndrome causes lasting sexual, neurological, and physical side effects in some people after taking finasteride.

Blocking Wnt/β-catenin signaling with EGF receptor is necessary for proper hair growth.

Some growth factors, while important for normal body functions, can cause diseases when not regulated properly.

FGF9 controls which receptors it binds to through a process where two FGF9 molecules join, and changes in FGF9 can lead to incorrect receptor activation.

The document concludes that understanding how adult stem and progenitor cells move is crucial for tissue repair and developing cell therapies.

NFIC helps human dental stem cells grow and become tooth-like cells.

ATP increases melanin production in skin after UV exposure, with the P2X7 receptor being crucial for this process.

Tissue stiffness affects hair follicle regeneration, and Twist1 is a key regulator.