Search
for
Sort by
Research
360-390 / 1000+ resultsresearch Homeostatic Control of Sebaceous Glands by Innate Lymphoid Cells Regulates Commensal Bacteria Equilibrium
In this research, authors found that skin-resident ILCs regulate sebaceous gland function and microbial balance, emphasizing an immune-epithelia system that supports host-microbe symbiosis.
research Critical Developmental Periods for Effects on Male Rat Genitalia Induced by Finasteride, a 5α-Reductase Inhibitor
Finasteride affects male rat genitalia development, causing abnormalities during specific pregnancy days.
research Hydroxyl radical mediates cisplatin-induced apoptosis in human hair follicle dermal papilla cells and keratinocytes through Bcl-2-dependent mechanism
In this study, cisplatin was found to induce cell death in human hair follicle cells through hydroxyl radical generation and Bcl-2 down-regulation, suggesting potential strategies for preventing chemotherapy-induced alopecia.
research Hypervitaminosis A
This article reports that hypervitaminosis A in both experimental rats and children leads to severe symptoms such as weight loss, bone issues, and skin problems, which resolve upon stopping vitamin A intake.
research Regulation of VDR by ΔNp63α is associated with inhibition of cell invasion
This study found that ΔNp63α directly regulates VDR expression, which in turn may reduce invasiveness in an epidermoid cancer cell line.
research Role of stem/progenitor cells in reparative disorders
This review discusses the roles of tissue-specific and mesenchymal stromal cells in tissue repair and reparative disorders, highlighting potential therapeutic targets for muscle, heart, and lung tissues.
research Generalized trichorrhexis nodosa
This study describes a case of generalized trichorrhexis nodosa and finds that defects in alpha-keratin chain formation and low cystine levels in hair may contribute to the condition.
research [Prevalence of cutaneous lesions in Freixo de Espada à Cinta].
In this study, the researchers reported a high prevalence of specific cutaneous lesions in the Freixo de Espada à Cinta population, with significant associations between demographic factors and lesion types.
research The profile of steroid hormones in human fetal and adult ovaries
In this study, researchers found that human ovaries at different life stages biosynthesize both canonical and non-canonical steroid hormones, with fetal ovaries showing higher enzyme activity related to estradiol and testosterone conversion compared to adult tissues.
research Distinct use of super-enhancer elements controls cell type–specific CD25 transcription and function
This study found that deleting specific super-enhancer regions in mice affects CD25 expression in a cell type-specific manner, leading to autoimmune alopecia in some cases and revealing distinct regulatory mechanisms for constitutive and inducible expression of CD25.
research Pigmented Epithelioid Melanocytoma (PEM)/Animal Type Melanoma (ATM): Quest for an Origin. Report of One Unusual Case Indicating Follicular Origin and Another Arising in an Intradermal Nevus
This study observed two cases of pigmented epithelioid melanocytoma suggesting potential differing origins: one from a hair follicle's outer root sheath and another from an intradermal nevus.
research Alternative synthesis of the anti-baldness compound RU58841
A new, less toxic and more efficient method to create the anti-baldness compound RU58841 was developed in 2014.
research Genome-Wide Association Study of Fiber Diameter in Alpacas
This study explored the genetic basis of fiber diameter in alpacas, identifying candidate genomic regions including four significant areas on VPA6, VPA9, VPA29, and an unassigned scaffold, using whole genome association analysis and a custom SNP microarray.
research Report from the Chair of the Media Relations Committee
This article announces that the ISHRS has commissioned its first consumer survey to explore negative perceptions of hair transplants, but it presents no new results.
research Unsaturated Halogenated Hydrocarbons
This article reviews the properties, uses, and toxic effects of eleven unsaturated halogenated hydrocarbons, highlighting the risks associated with compounds like dichloroacetylene, allyl chloride, and vinyl chloride, and reports no new experimental findings.
research Unsaturated Halogenated Hydrocarbons
This review discusses the uses and toxicological data of eleven unsaturated halogenated hydrocarbons, including dichloroacetylene, allyl chloride, hexachlorobutadiene, β-chloroprene, vinyl chloride, trichloroethylene, and perchloroethylene, but presents no new findings.
research Dose-Dependent Increases in Carotid Intima-Media Thickness Associated with Oral Minoxidil but Not Dutasteride in Healthy Young Males: A Randomized Controlled Pharmacological Trial
This study found that in healthy young men, oral minoxidil at 5 mg/day led to increased carotid intima-media thickness and vascular aging, suggesting potential cardiovascular side effects at higher doses. A dose-dependent effect was observed, while dutasteride displayed a favorable vascular profile without significant changes.
research A decade of hair-loss clinical trials: a registry-based analysis of studies registered on ClinicalTrials.gov
This registry-based analysis observed rapid growth in hair-loss clinical trials between 2015 and 2025, highlighting regional concentration, prevalent therapeutic categories, and diverse outcome reporting while emphasizing the need for standardization and broader representation.
research Table 1_A decade of hair-loss clinical trials: a registry-based analysis of studies registered on ClinicalTrials.gov.docx
This study analyzed hair-loss clinical trials from 2015 to 2025 and found that, while the number of registrations increased globally, research activity was concentrated in certain regions and varied in therapeutic approaches and outcome specifications.
research Rethinking pattern hair loss classification in the era of trichoscopy and artificial intelligence
This study suggests that traditional classification systems for pattern hair loss, while useful in the past, have limitations in accuracy and reproducibility, and highlights the potential of integrating digital imaging and AI to create more precise and biologically informed classification frameworks.
research Low-dose oral minoxidil (LDOM) and topical minoxidil: consensus recommendations for managing male and female pattern Hair loss in Hair transplant patients using a modified delphi process
This study developed consensus guidelines for the use of low-dose oral and topical minoxidil in male and female pattern hair loss, recommending specific doses, monitoring procedures, and timing of application around hair transplant surgeries.
research Low-dose oral minoxidil (LDOM) and topical minoxidil: consensus recommendations for managing male and female pattern Hair loss in Hair transplant patients using a modified delphi process
This study developed expert consensus guidelines on using low-dose oral and topical minoxidil for pattern hair loss around hair transplant surgery, recommending specific doses, monitoring practices, and timing of use for both male and female patients.
research Comparative efficacy of oral dutasteride and low-, medium-, and high-dose oral minoxidil: a six-month prospective trichoscopic and clinical study
This study found that oral minoxidil was associated with short-term improvements in clinical severity for androgenetic alopecia, whereas oral dutasteride did not show significant early clinical changes in the six-month follow-up.
research Low-dose oral minoxidil (LDOM) and topical minoxidil: consensus recommendations for managing male and female pattern Hair loss in Hair transplant patients using a modified delphi process
This study established consensus-based guidelines for using low-dose oral and topical minoxidil in managing pattern hair loss for patients undergoing hair transplant surgery, recommending specific dosages, monitoring procedures, and timing for initiation post-surgery.
research Developmental trajectory of hair cortisol concentrations across childhood
Hair cortisol levels decrease as children age, stabilizing around age 4.
research Using machine learning to identify predictors of maternal and infant hair cortisol concentration before and during the COVID-19 pandemic
Machine learning can help identify stress indicators in mothers and infants.
research Desmoplastic melanoma presenting as an alopecic patch in a young patient
This article reviews the epidemiology of desmoplastic melanoma and reports no new clinical findings, emphasizing higher risks in chronically sun-exposed older males.
research 331 Mitochondrial stress contributes to atopic dermatitis
This study found that innate lymphoid cells-type 1 can induce alopecia areata characteristics in human hair follicles both ex vivo and in vivo, challenging the view of it as solely an autoimmune disease driven by CD8+ T cells.
research ISHRS Dallas 1993: An Eye-Opening and Life-Changing Experience for Me and for the World of Hair Transplantation
This abstract reflects on the author's journey in hair restoration surgery since 1986, but it presents no new research findings.