37 citations
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February 2014 in “Journal of Dermatology” This study found that topical valproic acid significantly increased hair count in male patients with moderate androgenetic alopecia compared to placebo over 24 weeks.
556 citations
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September 2008 in “Genes & Development” This review summarizes how genetic studies using conditional β-catenin loss- and gain-of-function mice have advanced understanding of canonical Wnt signaling's role in embryonic development, adult stem cell maintenance, and cancer modeling.
118 citations
,
October 2013 in “Trends in Genetics” The AUTS2 gene is linked to neurological disorders and may affect human brain development and cognition.
30 citations
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October 2014 in “PLOS ONE” This study found that BAF200, a subunit of the PBAF chromatin remodeling complex, is crucial for heart development and coronary artery formation in mice, as its absence led to embryonic lethality with severe cardiac defects.
13 citations
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September 2011 in “Archives of dermatology” This case report describes a 3-year-old male with X-linked ichthyosis and associated neurologic abnormalities, identifying an unusual cortical development malformation and suggesting that abnormal hair banding may assist diagnosis.
5 citations
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January 2018 in “Javma-journal of The American Veterinary Medical Association” This case report documents the first successful management of accidental minoxidil toxicosis in a dog, resulting in full recovery after treatment with supportive care, including medications for blood pressure and potential toxicity mitigation.
This study found that Plakophilin 1 regulates innate immune responses in keratinocytes by controlling RNA helicase activity, balancing inflammation during epidermal immune challenges.
January 2025 in “Universidad de Córdoba Insitutional Repository (Universidad de Córdoba)” In this study, researchers observed that individuals with alopecia areata exhibited significant changes in scalp microbiota diversity and composition, which were linked to disease severity and inflammation markers, though it remains unclear if these microbial shifts are a cause or a result of hair loss.
September 2024 in “Egyptian Journal of Medical Human Genetics” This case report adds to the understanding of neurofibromatosis type 1 by documenting an Egyptian child with the condition alongside multiple unusual congenital anomalies, highlighting the importance of considering NF1 when these features are present.
July 2017 in “Clin-Alert” Different medications can cause serious side effects in some people.
2 citations
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November 2016 in “PubMed” In this study, lichen planus was associated with increased carotid intima media thickness, especially with longer disease duration, but was not an independent predictor of this condition.
119 citations
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March 2020 in “Frontiers in Bioengineering and Biotechnology” This review provides an overview of recent tissue engineering and regenerative medicine developments in Asia, highlighting significant advances, representative research achievements, and discussing future directions, without presenting new research results.
57 citations
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December 2018 in “JAMA Surgery” This systematic review suggests that current evidence does not support routinely discontinuing gender-affirming hormone treatments before surgery, especially testosterone and spironolactone, due to limited data on related perioperative risks.
48 citations
,
February 2013 in “Molecular and Cellular Endocrinology” This review discusses the presence of the StAR protein in 17 non-classical steroidogenic tissues, suggesting that advanced detection methods are needed for a complete understanding of its functions in these tissues.
38 citations
,
September 2019 in “Chinese Medical Journal” This review discusses the cardiovascular risks associated with anabolic-androgenic steroid use and reports that, despite known toxic effects, further research is needed to clarify the causality of these risks.
38 citations
,
January 2001 in “Neuroepidemiology” This paper discusses the limitations of clinical trials in evaluating combination treatment regimens for Alzheimer's disease and ischemic stroke, highlighting the extensive resources required for such trials.
27 citations
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February 2020 in “Journal of Cardiovascular Translational Research” This review discusses the role of sex hormones in cardiac hypertrophy and notes that estrogen provides protection against hypertrophy in pre-menopausal women, which is reduced after menopause but partially restored with estrogen therapy.
26 citations
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December 2016 in “Pharmacology & Therapeutics” This review discusses the paracrine properties of cardiac stem cells and pericytes in regenerative medicine for ischaemic diseases and reports no new clinical results.
15 citations
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February 2019 in “Journal of clinical medicine” In this animal study, atorvastatin co-administered with trastuzumab reversed trastuzumab-induced cognitive impairment (chemo-brain) and improved its anti-cancer efficacy without causing hair loss.
11 citations
,
December 2022 in “Arterial Hypertension” This joint position paper by several Polish medical societies examines guidelines and recommendations for managing conditions like obesity, hypertension, and liver disease, underscoring the importance of a collaborative, interdisciplinary approach in treatment. Results are not explicitly reported.
4 citations
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May 2019 in “Biology open” This study found that while testosterone administration reduced myocardial damage in gonadectomized rats after ischemia/reperfusion injury, Finasteride led to greater improvements, whereas 4-hydroxyandrostenedione worsened outcomes.
3 citations
,
November 2010 in “Rheumatic Diseases Clinics of North America” This article reviews how normal pregnancy changes can mimic rheumatologic disorders, emphasizing the importance of distinguishing these from true autoimmune inflammation, but reports no new evidence.
2 citations
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September 2018 in “Clinical Pediatrics” Most inconsolable crying in infants is not due to a serious cause, and a detailed check-up is typically enough to find the reason.
October 2024 in “Irish Journal of Medical Science (1971 -)” In this study, TENS of the T6 dermatome over a longer term was explored for its effects on weight, blood pressure, heart rate, and appetite-regulating hormones in obese subjects with moderate obstructive sleep apnea; however, results are not reported in the abstract.
May 2021 in “Boletín latinoamericano y del Caribe de plantas medicinales y aromáticas” This study found that ethanolic extracts of Microsechium helleri showed notable antioxidant, hypoglycemic, and cardioprotective activities, while chloroformic extracts exhibited significant anti-inflammatory effects in experimental models.
January 2018 in “Przegla̧d dermatologiczny” This research review discusses the potential link between androgenetic alopecia and increased cardiovascular risk but does not report any new experimental findings.
3 citations
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August 2023 in “Drug safety” This source reports that trastuzumab deruxtecan improves outcomes in HER2-positive and HER2-low metastatic breast cancer, emphasizing the need for careful adverse event monitoring, particularly for interstitial lung disease, and managing emetic risk to maximize benefits.
August 2016 in “PolyPublie (École Polytechnique de Montréal)” This study observed early cardiac effects in young minipigs following high-dose doxorubicin chemotherapy, with a decrease in heart function and changes in cardiac MRI measurements compared to controls.
February 2012 in “InTech eBooks” This review discusses the impact of polycystic ovary syndrome on cardiovascular risk and reports no new clinical findings.
7 citations
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November 2018 in “International Journal of Research -GRANTHAALAYAH” This study introduces a tabletop technique demonstrating that endogenous biomagnetic fields from human hair can induce red blood cells agglutination and Rouleaux formations.