research Selection Signatures in Goats Reveal a Novel Deletion Mutant Underlying Cashmere Yield and Diameter
A specific genetic deletion in goats affects cashmere yield and thickness.
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research WNT Signaling in the Control of Hair Growth and Structure
The research shows that a gene called Wnt3 affects hair growth and structure, causing short hair and balding when overactive.
research APCDD1 Is a Novel Wnt Inhibitor Mutated in Hereditary Hypotrichosis Simplex
A gene called APCDD1, which controls hair growth, is found to be faulty in a type of hair loss called hereditary hypotrichosis simplex.
research Macrophages Induce AKT/β-Catenin-Dependent Lgr5+ Stem Cell Activation and Hair Follicle Regeneration Through TNF
Macrophages help regrow hair by activating stem cells using AKT/β-catenin and TNF.
research Transcriptome Analyses of Reprogrammed Feather/Scale Chimeric Explants Revealed Co-Expressed Epithelial Gene Networks During Organ Specification
Key genes can rewire networks, changing skin appendage types.
research Antioxidant and Antiproliferative Activity of Finasteride Against Glioblastoma Cells
High-dose finasteride may help treat glioblastoma but needs localized delivery for effectiveness.
research Spontaneous Tumor Regression in Keratoacanthomas Is Driven by Wnt/Retinoic Acid Signaling Cross-Talk
Skin tumor regression is helped by retinoic acid signaling blocking Wnt signaling.
research Skin Shedding and Tissue Regeneration in African Spiny Mice (Acomys)
African spiny mice can regenerate skin, hair, and cartilage, but not muscle, and their unique abilities could be useful for regenerative medicine.
research Topical Inhibition of the Electron Transport Chain Can Stimulate the Hair Cycle
Applying certain inhibitors to the skin can promote hair growth without harming cells.
research Basal Cells in the Epidermis and Epidermal Differentiation
The exact identity of skin stem cells and how skin cells differentiate is not fully known.
research Dermal β-Catenin Is Required for Hedgehog-Driven Hair Follicle Neogenesis
β-Catenin is essential for new hair growth after skin injury.
research In Vivo Imaging of Mammary Epithelial Cell Dynamics in Response to Lineage-Biased Wnt/β-Catenin Activation
Activating β-catenin in mammary cells leads to changes that cause early-stage abnormal growths similar to skin structures.
research Rapid Mechanosensitive Migration and Dispersal of Newly Divided Mesenchymal Cells Aid Their Recruitment into Dermal Condensates
Newly divided skin cells quickly move to join skin structures due to tissue tension and specific signals.
research Newly Born Mesenchymal Cells Disperse Through Rapid Mechanosensitive Migration
Newly born mesenchymal cells quickly spread out in response to tissue tension during early development.
research Discovering Hair Loss Treatments That Increase The Wnt/Beta-Catenin Signaling Pathway By High-Throughput Screening
Aminoacridine and Abemaciclib, especially combined with Minoxidil, show promise for treating hair loss.
research Combined Deletion of the Vitamin D Receptor and Calcium-Sensing Receptor Delays Wound Re-Epithelialization
Removing vitamin D and calcium receptors in mice skin cells slows down skin wound healing.
research Skin Epidermis and Adnexa Regrowth Induced by Treatment With Artificial Dermal Template After Full-Thickness Skin Wound
Artificial dermal template treatment can stimulate complete skin and hair follicle regrowth.
research Tissue Engineering of Human Hair Follicles Using a Biomimetic Developmental Approach
Researchers created human hair follicles using a new method that could help treat hair loss.
research Treatment of Rheumatoid Arthritis Patients: Comparative Efficacy of Four Treatment Regimens
MTX and GC combinations are the most effective for early rheumatoid arthritis.
research Comparative Analysis of Safety Data of Four Treatment Regimens in Early Rheumatoid Arthritis Patients
Methotrexate plus prednisolone had the fewest serious side effects.
research Safety of Four Treatment Regimens in Early Rheumatoid Arthritis
All four treatments for early rheumatoid arthritis had similar safety profiles.
research The Metabolites of Bifidobacterium Longum BB536 Alleviate DHT-Damaged Human Dermal Papilla Cells by Activating WNT/β-Catenin Signaling
Bifidobacterium longum BB536 metabolites may help treat hair loss by repairing and promoting hair cell growth.
research Tissue Engineered Human Hair Follicles from Genetically, Environmentally, and Extrinsically Reprogrammed Dermal Papilla Cells
Researchers developed a method to grow human hair follicles using 3D-printed skin models and modified cells.
research Synthetic Developmental Tissue Engineering of Human Hair Follicles
Scientists have found a way to grow hair follicles from human cells in a lab, which could help treat hair loss and skin damage.
research Direct Hair Growth Promoting Effects of Mycophenolic Acid
Mycophenolic acid may help hair grow by activating pathways important for hair growth.
research Stem Cells Sheltered from Air-Raids Repair Airways
Myoepithelial cells can repair airways after severe injury.
research Enhancing Hair Growth in Male Androgenetic Alopecia by a Combination of Fractional CO2 Laser Therapy and Hair Growth Factors
Laser therapy and hair growth factors significantly improve hair density in male baldness.
research Safety Data of Four Treatment Regimens in Early Rheumatoid Arthritis Patients
All four treatments for early rheumatoid arthritis had similar and mostly mild side effects.
research Wnt-Dependent De Novo Hair Follicle Regeneration in Adult Mouse Skin After Wounding
Hair follicles can regrow in wounded adult mouse skin using a process like embryo development.
research Exosomal MicroRNAs Derived from Dermal Papilla Cells Mediate Hair Follicle Stem Cell Proliferation and Differentiation
Exosomes from dermal papilla cells help hair growth by making hair follicle stem cells multiply and change.