This study found that the proteins Par3, mInsc, and Gαi3 cooperate to regulate LGN polarization and promote perpendicular cell divisions during murine epidermal morphogenesis.
40 citations
,
September 2019 in “World journal of clinical cases” In this case report, an 86-year-old man experienced new hair growth and color change in alopecia areata after receiving fecal microbiota transplantation for noninfectious diarrhea.
14 citations
,
March 2016 in “Mechanisms of Development” This study found that BNC2 is critical for hair follicle regeneration and other developmental processes, as Bnc2−/− mice exhibit incomplete hair follicle development and developmental defects, and BNC1 cannot substitute for BNC2.
6 citations
,
September 2021 in “Autophagy” In this study on mouse preputial glands, suppressing ATG7-dependent autophagy delayed age-related changes, affected lipid metabolism, and reduced pheromone production, highlighting autophagy's roles in glandular homeostasis and cell breakdown.
3 citations
,
November 2019 in “Journal of dermatology” This case report details the successful use of oral itraconazole in treating a giant tufted angioma with hair loss that developed during pregnancy, leading to significant symptom relief and hair regrowth after discontinuation of the medication.
1 citations
,
April 2016 in “PubMed” This study found that co-transplanting mouse epidermis and dermis cells induced new hair follicle formation, while isolated or cultured dermis cells contributed to follicle-related structures differently.
March 2025 in “International Journal of Trichology” This study found that, in female patients with pattern hair loss, injections of adipose-derived stem cells increased hair density and thickness, reduced perifollicular inflammation, and enhanced markers associated with hair cycle regeneration.
January 2023 in “RSC Advances” This study found that two eco-friendly analytical methods for quantifying Finasteride and Tadalafil in a new dosage form were effective, green, and suitable for quality control.
260 citations
,
January 2020 in “Nature” Stress can cause hair to turn gray by depleting stem cells.
101 citations
,
July 1998 in “Journal of Investigative Dermatology” This study found that UV exposure in human skin induces IL-10 production by macrophages, while Langerhans cells are depleted and their IL-12 production is downregulated.
45 citations
,
August 2009 in “American Journal Of Pathology” Noggin promotes skin tumors by activating certain cell signaling pathways.
40 citations
,
August 2021 in “International Journal of Molecular Sciences” This review discusses the role of fascial mobilization in wound healing and its potential implications for treating chronic skin wounds and scarring, but reports no new clinical results.
29 citations
,
January 2021 in “G3 Genes Genomes Genetics” This study identified a 195 bp duplication in crested chickens that causes large crest feathers and can be associated with cerebral hernia in some breeds, but not all.
29 citations
,
November 2011 in “Cell stress & chaperones” This study demonstrated that quercetin effectively treated alopecia areata and prevented its onset in a mouse model, suggesting potential for clinical applications in managing the condition.
21 citations
,
September 2003 in “Journal of Clinical Investigation” This paper reports that noggin inhibits BMP-2 and BMP-4 functions by binding and blocking their interaction with the BMP receptor, impacting multiple developmental processes without presenting new research results.
9 citations
,
October 2017 in “Frontiers in plant science” This study found that the peach gene CTG134 mediates auxin-ethylene crosstalk, affecting root hair growth and hormone-regulated processes in plants.
3 citations
,
May 2014 in “Urologia Journal” This review discusses how 5α-reductase inhibitors affect PSA levels in benign prostatic hyperplasia treatment and their role in prostate cancer screening, but reports no new clinical findings.
1 citations
,
January 2024 CaBP1 and CaBP2 are necessary for proper hearing and neurotransmission in the ear's inner hair cells.
June 2023 in “Journal of biological chemistry/The Journal of biological chemistry” This study on Sdr16c5/Sdr16c6-null mice found that inactivating these genes significantly increased Meibomian gland secretions and altered lipid profiles but had a subtle impact on sebogenesis, suggesting the genes control a bifurcation point in meibogenesis pathways.
May 2025 in “Journal of the ASEAN Federation of Endocrine Societies” This case study highlights a testosterone- and cortisol-secreting adrenal oncocytic neoplasm in an 18-year-old woman, illustrating the role of surgical excision in resolving hyperandrogenism and restoring menstruation.
July 2024 in “Journal of Dermatological Treatment” In this case report, a 6-year-old boy with hidrotic ectodermal dysplasia 2 caused by GJB6 mutations showed no significant hair improvement with age, despite treatment with botanical extracts and Minoxidil.
January 2024 in “Biology of sex differences” This animal study observed that dihydrotestosterone increased arterial stiffness and decreased estrogen receptor expression in female mice, potentially impacting cardiovascular health in contexts of androgen use.
CaBP1 and CaBP2 are necessary for proper hearing and neurotransmission in the ear's inner hair cells.
January 2024 in “Case Reports in Endocrinology” In this case report, significant improvements in a 58-year-old male with severe refractory myasthenia gravis and concurrent alopecia areata were observed following a cortisone taper, suggesting a potential therapeutic role, especially after thymectomy.
July 2022 in “Biomedicines” This study found that 4-aminopyridine significantly enhanced skin wound healing by accelerating wound closure, improving skin architecture, and promoting hair follicle neogenesis and tissue regeneration.
245 citations
,
January 2010 in “Blood” This study suggests that antihepcidin antibodies may effectively treat inflammatory anemia by manipulating iron metabolism, based on experiments conducted in mouse models and hHepc knock-in mice.
151 citations
,
August 2011 in “The EMBO Journal” The enzyme PA-PLA1α is important for proper hair follicle development.
82 citations
,
January 2011 in “New Phytologist” This study demonstrated that AtVLN4 plays a role in root hair growth by regulating actin organization in a calcium-dependent manner.
67 citations
,
July 2011 in “Clinical, cosmetic and investigational dermatology” This review discusses various therapeutic agents for alopecia areata, categorized by efficacy and safety, and highlights the lack of curative treatments and long-term outcome studies.
42 citations
,
July 2021 in “Frontiers in Cell and Developmental Biology” This review examines the regeneration capabilities of skin, oesophagus, and oral mucosa, highlighting the oral mucosa's unique scarless healing properties and the potential of cell therapy to improve scar reduction in wound healing.