research Eph/Ephrin Signaling in Epidermal Differentiation and Disease
Eph/ephrin signaling is important for skin cell behavior and could be targeted to treat skin diseases.
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research One of These Things Is Not Like the Others: The Idea of Precedence in Health Technology Assessment and Coverage Decisions
The conclusion is that formalizing how past decisions influence current health technology assessments could improve the credibility and defense of coverage decisions.
research FOXN1 Deficient Nude Severe Combined Immunodeficiency
FOXN1 gene mutations cause a rare, severe immune disease treatable with cell or tissue transplants.
research Modeling of Chronic Radiation-Induced Cystitis in Mice
Researchers developed a mouse model that successfully mimics the bladder damage seen in humans after radiation therapy.
research Age-Related Hair Pigment Loss
Graying hair happens due to aging and might be delayed by new treatments.
research Differential Impact of Environmental Factors on Systemic and Localized Autoimmunity
Environmental factors like diet and vitamin levels, especially Vitamin D, can affect autoimmune diseases differently, with lifestyle changes potentially improving outcomes.
research Gene Therapy: Recent Advances and Applications in Dermatology
Gene therapy shows promise for treating skin disorders and cancer, but faces technical challenges.
research Development of PEGylated Liposomes
PEGylated liposomal doxorubicin improves cancer treatment effectiveness and reduces side effects like heart damage and hair loss.
research PI3K-Akt-mTOR and Associated Signaling Pathways as Molecular Drivers of Immune-Mediated Inflammatory Skin Diseases: Update on Therapeutic Strategy Using Natural and Synthetic Compounds
Certain natural and synthetic compounds may help treat inflammatory skin diseases by targeting a specific signaling pathway.
research The Optimal Holding Solution and Temperature for Hair Follicle Grafts
Best solution for storing hair grafts is saline with ATP at 4 degrees Celsius, but no definitive best method was confirmed.
research Recent Developments in Luteolin-Loaded Nanoformulations for Enhanced Anti-Carcinogenic Activities: Insights from In Vitro and In Vivo Studies
Nanoformulations improve luteolin's effectiveness as a cancer treatment.
research The Human Gut Chemical Landscape Predicts Microbe-Mediated Biotransformation of Foods and Drugs
The study developed a tool to predict how gut microbes process foods and drugs, showing that similar compounds often share metabolic pathways and effects.
research Treatment of Male Rats with Finasteride, an Inhibitor of 5alpha-Reductase Enzyme, Induces Long-Lasting Effects on Depressive-Like Behavior, Hippocampal Neurogenesis, Neuroinflammation, and Gut Microbiota Composition
Finasteride treatment in male rats causes long-lasting effects on depression-like behavior, brain cell growth, inflammation, and gut bacteria composition.
research Alterations of Gut Microbiota Composition in Post-Finasteride Patients: A Pilot Study
Post-finasteride patients show changes in gut bacteria, possibly causing various symptoms.
research Added Dietary Vegetables And Fruits Improved Coat Quality Of Capybara In Seoul Zoo, Republic Of Korea: A Case Study
Adding more vegetables and fruits improved capybaras' coat quality and health.
research Disease-Modifying Therapy in Multiple Sclerosis: Strategies for Optimizing Management
A comprehensive approach to educating patients and managing side effects is crucial for improving adherence to multiple sclerosis treatments and patient quality of life.
research Hair Regrowth Following Fecal Microbiota Transplantation in an Elderly Patient with Alopecia Areata: A Case Report and Review of the Literature
An elderly man's hair grew back after a treatment that transferred healthy gut bacteria.
research Post-Finasteride Syndrome: An Emerging Clinical Problem
Post-finasteride syndrome causes lasting sexual, neurological, and physical side effects in some people after taking finasteride.
research Multiple Sclerosis: Side Effects of Interferon Beta Therapy and Their Management
The article suggests managing interferon beta therapy side effects in MS with dose adjustments, medications, and patient education.
research Aldesleukin
Aldesleukin can treat certain cancers and increase HIV patient CD4+ counts but often causes severe side effects.
research Post-Finasteride Syndrome and Post-SSRI Sexual Dysfunction: Two Clinically Similar Conditions
Some people experience lasting sexual, psychological, and sleep problems after using finasteride or SSRI antidepressants, possibly due to similar underlying causes.
research Disease Modifying Agent Related Skin Reactions in Multiple Sclerosis: Prevention, Assessment, and Management
The article concludes that proper injection techniques and patient education can prevent serious skin reactions from multiple sclerosis medications.
research Repurposing DPP4-Inhibition to Improve Hair Follicle Activation and Regeneration
Blocking DPP4 can potentially speed up hair growth and regeneration, especially after injury or in cases of hair loss.
research Diseases of the Skin: Drug Ill Effects on the Skin
All medications can cause skin rashes, often without a clear cause, and better tests are needed to identify these drug-related skin issues.
research Keratin Disorders: From Gene to Therapy
New treatments targeting specific genes show promise for treating keratin disorders.
research Sulfation of Minoxidil by Multiple Human Cytosolic Sulfotransferases
Minoxidil breakdown varies by enzymes, affecting hair loss treatment effectiveness.
research Straight Hair Associated with Interferon-Alpha Plus Ribavirin in Hepatitis C Infection
ALA-PDT is effective and safe for chronic X-ray dermatitis, providing complete or partial remission.
research The Effect of St. John's Wort on the Pharmacokinetics, Metabolism, and Biliary Excretion of Finasteride and Its Metabolites in Healthy Men
St. John's wort increases finasteride metabolism, reducing its effectiveness; use caution when combining them.
research Therapeutic Effect of Rumex Japonicus Houtt. on DNCB-Induced Atopic Dermatitis-Like Skin Lesions in Balb/c Mice and Human Keratinocyte HaCaT Cells
Rumex japonicus Houtt. may be an effective treatment for atopic dermatitis by reducing inflammation.
research Basic Mechanisms of SARS-CoV-2 Infection: Implications for Endocrine Systems
SARS-CoV-2, the virus causing COVID-19, can affect all endocrine organs and systems, altering their function and potentially leading to disorders. Factors like diabetes and obesity increase infection risk and severity. Understanding these effects is key for effective treatment.