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September 2016 in “Veterinary dermatology” In this study, a 12-year-old intact male wirehaired fox terrier with testicular neoplasia and alopecia universalis was successfully treated for the alopecia using a combination of ciclosporin and ketoconazole, leading to complete hair regrowth.
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January 2016 in “Journal of Biosciences and Medicines” This study found that the ACTH/MC2R system is important for hair cycle regulation, with deficiencies in MC2R leading to altered hair growth phases in mice.
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June 2013 in “Annals of the Rheumatic Diseases” This study observed that while all DMARD regimens had similar safety profiles, the leflunomide group experienced the most serious side effects leading to therapy discontinuation.
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January 2013 in “UNICA IRIS Institutional Research Information System (University of Cagliari)” This study found that chronic treatment with EE/LNG in female rats decreased brain concentrations of allopregnanolone, leading to reduced social and sexual behaviors; progesterone administration reversed these effects, except when finasteride was used to block the increase.
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April 2007 in “The FASEB Journal” In this study, D6D knockout mice showed severe deficiency in AA and DHA, leading to unexpected effects on skin health, fertility, and immune cell development.
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March 2005 in “Zentralblatt für Gynäkologie” This case report describes a postmenopausal woman with hirsutism and androgenetic alopecia, where imaging ruled out malignancy and selective venous sampling indicated increased testosterone from the right adrenal vein, leading to a recommendation for right adrenalectomy and oophorectomy.
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April 1995 in “Annals of Plastic Surgery” This study describes the Mercedes incision technique, which may improve hair transplant results by reducing graft compression and row cropping, leading to a more natural appearance.
August 2026 in “Frontiers in Pharmacology” In this case report, a 27-year-old woman experienced severe multisystem toxicity, including toxic encephalopathy, vision, and hearing loss, after ingesting selenium at occupationally high doses, suggesting such exposure can lead to previously unreported effects of vision and hearing impairment.
July 2026 in “Industrial and Domestic Waste Management” This study synthesized silver nanoparticles using Gandaria stem bark extract, finding that nanoparticles at a 4% concentration were particularly effective for selectively detecting mercury over lead and calcium, making them suitable as preliminary detection materials for mercury in facial whitening creams.
July 2026 in “Clinical Case Reports” This single-patient case study reported promising results for severe, corticosteroid-resistant alopecia areata, with treatment using exosomes derived from mesenchymal stromal cells leading to almost complete hair regrowth in 12 weeks and favorable changes in inflammatory markers, suggesting potential for further investigation.
June 2026 in “Skin Appendage Disorders” This source reviews the use of topical tretinoin with minoxidil for androgenetic alopecia, indicating that while combined use may convert some minoxidil nonresponders to responders, clinical evidence is limited and increased absorption may lead to irritation concerns.
June 2026 in “Indian Journal of Case Reports” This source reports a rare case of a 10-year-old child developing periorbital milia as an unusual cutaneous manifestation of chronic graft-versus-host disease following allogeneic stem cell transplantation, suggesting that immune-mediated epidermal disruption may lead to milia formation.
May 2026 in “International Journal of Health Management Review” This study found that the use of high pH chemical agents for hair straightening can cause significant damage to hair, including protein degradation and weakened fiber strength, and may lead to permanent scalp conditions like contact dermatitis and cicatricial alopecia.
May 2026 in “AlQalam Journal of Medical and Applied Sciences” In this study, researchers found that relying solely on ferritin to assess iron status in young females with higher BMI may lead to inaccurate diagnoses of iron deficiency due to inflammation-related ferritin elevation.
May 2026 in “Inovasi Kesehatan Global” This case report describes a 7-year-old boy with Tinea favosa caused by Trichophyton schoenleinii, treated for 8–12 weeks with oral griseofulvin and ketoconazole cream, leading to recovery from crusts and inflammation but permanent hair loss in some areas.
In a phase 2 trial, researchers tested a topical formulation for alopecia areata and found significant hair regrowth with the treatment, but these improvements did not lead to substantial enhancements in health-related quality of life.
April 2026 in “Antibodies” This review discusses the uncertain role of immune factors, particularly autoantibodies, in the development of alopecia areata and emphasizes that identifying key autoantigens could lead to targeted immunotherapies.
March 2026 in “Frontiers in Cell and Developmental Biology” This review reports that transcriptional and epigenetic mechanisms in epithelial stem cells guide their fate in the epidermis and hair follicles, crucial for skin homeostasis, but disruptions can lead to disease.
March 2026 in “JID Innovations” In a mouse model study, researchers found that mutations in Aire reduced alopecia areata frequency, while Notch4 mutations did not lead to the disease, likely due to proximity with a resistance gene.
This abstract does not report results, instead, it explores the often personal and emotional experience of noticing hair loss, noting the lack of clear medical symptoms and the potential social impact, which can lead to confusion about seeking appropriate medical care.
February 2026 in “Clinical Cosmetic and Investigational Dermatology” This study found that a family history of androgenetic alopecia and specific trichoscopic signs are strong predictors of female pattern hair loss, leading to a nomogram model for risk prediction.
January 2026 in “Preprints.org” This review explores current knowledge on fibroblast lineage specification and its impact on scar-free wound healing, noting that early fetal skin fibroblasts support regeneration, while later developmental shifts lead to fibrosis, highlighting potential strategies to reprogram adult fibroblasts for regenerative repair.
This study observed that exosomes derived from adipose-derived stem cells significantly enhanced bone marrow mesenchymal stem cell migration and osteogenesis, leading to improved bone regeneration in a rat model of calvarial defects.
January 2026 in “Advanced Science” In this study, a chronotherapeutic bilayer dressing system showed enhanced diabetic wound healing in a model by reducing inflammation through polyphenols and promoting repair with sustained PDGF-BB delivery, leading to faster re-epithelialization and hair follicle regeneration.
January 2026 in “AppliedMath” This study explored a mechanism for making Turing pattern formations more predictable and robust by isolating pattern modes to prevent their sensitivity to initial conditions, which can lead to different outcomes from minor initial changes.
This case report illustrates that prompt diagnosis and management of myositis, a rare manifestation of Systemic Lupus Erythematosus, can lead to favorable patient outcomes, as demonstrated by symptom resolution and normal electromyocardiography findings.
December 2025 in “Cureus” In this case report, a unique immunological mechanism was observed in an 11-year-old girl where the presence of one autoimmune disease appeared to prevent the manifestation of another, leading to the withdrawal of one type of lesion when another appeared.
December 2025 in “Reports — Medical Cases Images and Videos” This case report highlights the rarity and complex differential diagnosis of discoid lupus erythematosus, emphasizing that immunosuppressive therapy in such cases can lead to serious complications like pulmonary tuberculosis.
November 2025 in “Journal of Clinical Medicine” This review article explores the potential systemic nature of alopecia areata, highlighting the association with ocular abnormalities and suggesting that shared pathogenic pathways may lead to eye symptoms occurring at younger ages than usual.
November 2025 in “Frontiers in Immunology” This review integrates studies on mouse models and human clinical observations to highlight the role of immune cells in skin development and how their dysregulation leads to skin disorders, suggesting potential therapeutic pathways for skin regeneration.