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This study highlights that lower testosterone in men and higher testosterone in women are linked to increased risks of metabolic syndrome and type 2 diabetes, with associated skin diseases indicating potential cardiovascular complications.

This article reviews the structure and function of hair follicles, diagnostic approaches, and treatments for nonscarring alopecias, but reports no new clinical results.

This review highlights that while sonidegib and vismodegib offer promising treatment options for advanced basal cell carcinoma, their use is often limited by treatment-emergent adverse events, which can be managed through protocol modifications and supportive interventions.

This source suggests that spironolactone, a potassium-sparing diuretic, is underutilized in dermatology despite evidence showing its potential benefits for female acne, hidradenitis suppurativa, and female androgenetic alopecia, noting its long-term safety and reduced need for additional testing in young women.

This review discusses the importance of heme oxygenase in skin physiology and disease, but it reports no new clinical results; the authors highlight its potential as a treatment target for conditions like atopic dermatitis and psoriasis.

This study found an association between low serum ferritin levels and alopecia in women, suggesting a potential role of iron in hair health and paving the way for further research.

This review outlines the complexities and varied manifestations of polycystic ovary syndrome, highlighting challenges in diagnosis and management but reports no new clinical findings.

This study explored the immune environment of the hair follicle's bulge region and suggested that its unique signaling may prevent melanoma formation by lacking necessary proinflammatory signals for full oncogenic transformation, indicating potential strategies for melanoma prevention by replicating this immune-privileged environment.

This study reported that in the California Ground Squirrel, certain elements bioaccumulate in hair, providing baseline data for environmental health assessments.

This study observed that testosterone therapy in transgender men enhances both physical and mental health, is safe in the short and middle term with proper follow-up, and highlights the need for endocrinologists to provide gender-affirming care despite its limited presence in medical education.

This article discusses the role of testosterone in the formation of male characteristics, muscle and bone development, and its impact on skin and hair, but provides no new clinical results.

Low androgen levels can still cause female pattern hair loss.

This review discusses the roles of glucocorticoid and sex hormone receptors in the skin and their clinical importance, but reports no new research findings.

This review discusses current treatments and management strategies for hidradenitis suppurativa, noting the mixed effectiveness of various therapies, including surgery, antibiotics, and hormonal treatments, but reports no new clinical findings.

This chapter discusses the current developments in Traditional Chinese Medicine for treating PCOS but reports no new clinical results, emphasizing the need for further research in this area.

This study identified 8-hydroxy germacrene B from Curcuma aeruginosa as a highly potent in-vitro 5-alpha reductase inhibitor with significant anti-androgenic activity, while exhibiting mild cytotoxicity on prostate cancer cells without affecting human dermal papilla cells at tested concentrations.

This study found that plantar dermis matrix homogenate can partially restore the regenerative capacity of hair follicles impaired in culture, with CTHRC1 playing a critical role in this process.

This review discusses the role of biotin in metabolism and the consequences of its deficiency, reporting no new clinical results.

This review discusses skin appendages like hair and nails as indicators of local and systemic pathologies, emphasizing conditions such as inflammatory diseases and infections, but reports no new clinical findings.

This review discusses the cosmetic and health implications of hirsutism and highlights its potential link to serious underlying disorders, but it presents no new clinical findings.

This review examines nanozymes as promising tools for cancer diagnosis and therapy due to their enzyme-mimicking catalytic properties and highlights their challenges, including biosafety and clinical translation, alongside potential improvements through biomimetic designs, particularly utilizing exosome-based strategies for targeted delivery to tumors.

This review discusses the role of metabolism in maintaining adult stem cell homeostasis with aging and highlights the potential benefits of dietary restrictions on stem cell function and longevity. It reports no new clinical results and emphasizes the need for further molecular studies.

This review examines the use of natural remedies, including various herbs, for treating polycystic ovary syndrome, but reports no new clinical results.

This chapter reviews various dermatological drugs and treatments, highlighting adverse effects, with no new clinical findings reported.

This study introduced ElixirSeeker2, a computational framework for designing anti-aging peptides, and found that some newly identified peptides significantly delayed cellular senescence and enhanced cellular and locomotor functions in aged Caenorhabditis elegans.

This case report describes a young female with pediatric SLE and latent TB who was found to have gastrointestinal tuberculosis, a rarely recognized and often misdiagnosed condition, highlighting the diagnostic challenges and need for early recognition in such cases.

This review indicates that hair loss negatively impacts psychological well-being and quality of life, highlighting the importance of comprehensive management, including psychological assessment and sleep improvement, to enhance patients’ quality of life.

This review reports that transgender individuals undergoing hormonal therapy for gender transition face increased risks of cardiovascular disorders, brain tumors, changes in bone density, metabolic disorders, and other health issues, while highlighting the necessity of this therapy for gender transformation.

In this review, the authors explored current and novel treatment options for androgenetic alopecia, noting both FDA-approved pharmacologic treatments like Minoxidil and Finasteride and various non-pharmacologic and surgical methods, including hair transplantation and scalp micro-pigmentation.

This article reviews how various medications, such as antihypertensives, chemotherapy, and hormonal contraceptives, are associated with negative effects on sexual desire and function but reports no new clinical results.