January 2025 in “Indian Journal of Biochemistry and Biophysics” This study found that the uric acid to creatinine ratio had excellent diagnostic ability for polycystic ovary syndrome, with significant associations to metabolic and hematologic changes in PCOS patients.
This study found a significant association between androgenetic alopecia and metabolic syndrome, with AGA patients showing higher BMI, waist circumference, blood glucose, and cholesterol levels compared to controls.
January 2024 in “Journal of lipid research” In this study, finasteride was found to reduce cholesterol levels and delay atherosclerosis in LDL receptor-deficient mice, and men using finasteride reported lower cholesterol levels, suggesting potential cardiovascular benefits by improving lipid profiles.
January 2024 in “Circulation” This commentary explores the role of PCSK9 as a target for drug development, underscoring that individuals with PCSK9 loss-of-function mutations experience significantly lowered LDL cholesterol levels and reduced coronary events, suggesting that full inactivation of PCSK9 is effective and safe.
October 2023 in “Pakistan Journal of Medical & Health Sciences” In this study examining male patients with androgenetic alopecia, 63.1% were found to have dyslipidemia, with more severe hair loss significantly associated with higher lipid abnormalities, suggesting a link to cardiovascular risk factors.
September 2023 in “PubMed” This study reviewed baricitinib's efficacy and safety for treating alopecia areata and found that more patients achieved significant hair regrowth with baricitinib compared to placebo in two phase III trials. Mild to moderate side effects were reported, with additional study suggested for long-term effects.
January 2007 in “Fashion & Textile Research Journal” This study found that ethanol extracts of A. koreanum improved serum cholesterol levels and protein recovery in rats with dry skin compared to water extracts.
January 1986 in “Journal of Steroid Biochemistry” Lower testosterone levels in men may be linked to a higher risk of severe coronary artery disease.
December 2021 in “Benha Journal of Applied Sciences” This study found that high serum alarin levels were linked to both androgenetic alopecia and metabolic syndrome, increasing with the severity of AGA.
June 2021 in “Egyptian Journal of Dermatology and Venereology” This study found that psoriasis, acne, and androgenetic alopecia are associated with an atherogenic lipid profile, suggesting an increased risk of atherosclerosis and cardiovascular disease, especially among psoriasis patients.
December 2020 in “Benha Journal of Applied Sciences” This study found that patients with androgenetic alopecia had significantly higher serum Osteopontin levels, which were positively associated with metabolic syndrome components, suggesting a potential role in its pathogenesis.
October 2018 in “International Journal of Research in Dermatology” In this study, androgenetic alopecia patients had a significantly higher prevalence of metabolic syndrome and related metabolic disorders compared to those without the condition.
December 2013 in “Tehran University Medical Journal TUMS Publications” In this study, no significant relationship was found between androgenetic alopecia and hyperlipidemia, but higher levels of cholesterol, LDL, and triglycerides in AGA patients may suggest an increased risk of coronary heart disease.
January 2021 in “Menoufia Medical Journal” This study found that patients with early-onset androgenetic alopecia had significantly higher levels of fasting blood sugar, triglycerides, and cholesterol, suggesting an increased risk of developing coronary artery disease.
January 2021 in “Menoufia Medical Journal” This study found a significant correlation between metabolic syndrome components, particularly waist circumference and hypertension, and female pattern hair loss.
May 2015 in “Scientific journal of Kurdistan University of Medical Sciences” Men with early-onset baldness may have a higher risk of heart disease.
January 2004 in “Journal of Clinical Dermatology” This study found significant differences in serum total lipid, phospholipid, and triglyceride levels between patients with androgenetic alopecia and those without but no differences in LDL, HDL, or total cholesterol.
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January 2017 in “Przegla̧d dermatologiczny” This study found that patients with skin tags had a high prevalence of metabolic syndrome, prompting recommendations for screening underlying conditions like diabetes and hypertension.
January 2015 in “IP Indian journal of clinical and experimental dermatology” This study found statistically significant associations between female androgenetic alopecia and certain components of metabolic syndrome, such as increased waist circumference and hypertriglyceridemia, in the Kashmiri population.
March 2020 in “Journal of evolution of medical and dental sciences” In this study, the vertex type of male pattern baldness was associated with increased cardiovascular risk factors, suggesting it may serve as a marker for cardiovascular evaluation in men.
November 2021 in “World Family Medicine Journal /Middle East Journal of Family Medicine” This review discusses evidence from recent clinical trials showing inclisiran effectively lowers LDL cholesterol levels in patients with cardiovascular disease, leading to its use in the UK despite not being approved by the FDA.
June 2017 in “Journal of The European Academy of Dermatology and Venereology” This meta-analysis found that patients with androgenetic alopecia have an atherogenic lipid profile, with higher LDL, triglycerides, and total cholesterol, and lower HDL, potentially explaining increased cardiovascular risk.
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July 2012 in “British journal of dermatology/British journal of dermatology, Supplement” This report suggests a causal connection between hyaluronic acid filler injections and the development of xanthelasma, possibly through an inflammatory reaction that increases vascular permeability and LDL leakage.
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June 2015 in “International Journal of Dermatology” In this study, non-obese females with early-onset androgenetic alopecia showed higher total cholesterol, LDL cholesterol, triglycerides, and atherogenic index, and lower HDL cholesterol compared to controls, suggesting an association with adverse cardiovascular risk factors.
This study introduced Cadd4, a peptide-based degrader developed using computer-aided drug design, which effectively reduced PCSK9 levels and increased LDL receptor expression, resulting in decreased plasma cholesterol and LDL-C levels in hypercholesterolemic mice, without liver toxicity.
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November 2023 in “Global Advances in Integrative Medicine and Health” In this study, the authors reported preliminary evidence that programs combining nutrition and exercise interventions can significantly reduce BMI and LDL levels, suggesting these elements are important for lifestyle modification.
November 2024 in “SKIN The Journal of Cutaneous Medicine” This study observed that patients with severe alopecia areata treated with baricitinib experienced increases in total cholesterol, LDL-C, and HDL-C, consistent with a JAK inhibitor class effect, but the mean increase was modest and lipid-lowering medication initiation was infrequent.
7 citations
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February 2004 in “Canadian Journal of Anesthesia/Journal canadien d anesthésie” Pressure from surgical headrests can cause temporary hair loss in liver donors.
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August 2024 in “Journal of Cosmetic Dermatology” This study reported that oral isotretinoin can be an effective and safe treatment for acne vulgaris when used at the appropriate dosage, offering a low-complication option.
March 2026 in “Journal of Skin and Stem Cell” In this study, lower serum adiponectin levels and altered lipid profiles were observed in patients with periorbital melanosis, suggesting an association with metabolic syndrome.