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The Rotterdam Study found risk factors for elderly diseases, links between lifestyle and genetics with health conditions, and aimed to explore new areas like DNA methylation and sensory input effects on brain function.

Women with PCOS often have more body hair, acne, and skin darkening, and these signs are linked to metabolic issues like insulin resistance and high cholesterol.

The conclusion is that genetic changes in the glucocorticoid receptor can lead to conditions affecting stress response, immunity, and metabolism, requiring personalized treatment.

Ziziphus jujuba Mills may have health benefits, but more research is needed to confirm its safety and effectiveness.

Finasteride treats enlarged prostate and baldness, but may cause limited urinary improvement and sex-related side effects.

Testosterone therapy seems safe for short-term use in postmenopausal women with low sexual desire, but more research on long-term effects is needed.

The document concludes that the hCG protocol may help in obesity treatment and could be scientifically justified, but more research is needed.

Exemestane is effective and safe for treating certain breast cancers, with mild side effects, but needs more research on long-term effects.

Pica disorder in central Iraq is mainly found in females and is linked to low iron levels; treatment with iron improves most patients.

Men with male pattern baldness may have a higher risk of heart disease due to increased levels of a specific lipid in their blood.

The report concludes that PCOS is mainly a condition of excess male hormones and its definition may change as new information is discovered.

PCOS is a complex condition with major health impacts, needing more research for better diagnosis and treatment.

The bulletin provides guidelines for diagnosing and managing PCOS, suggesting weight loss, hormonal contraceptives, and diabetes screening, with clomiphene for infertility and various treatments for excess hair.

The guidelines suggest a detailed approach to diagnosing and treating lupus, with a focus on regular check-ups, personalized medicine, and a range of drug options for different cases.

Women with PCOS are more likely to have impaired glucose tolerance and type 2 diabetes, especially if they are Asian or obese.

High androgen levels in young women with PCOS are linked to higher blood pressure.

Testosterone therapy in transgender men has both desired effects like increased muscle mass and potential health risks such as higher cardiovascular risk.

Hair loss linked to higher heart disease risk in both men and women.

Olive oil compounds may help prevent cancer in animals, but human results are mixed.

Green tea may help with health issues like cancer, heart disease, and weight loss due to its high catechin content.

The document concludes that minoxidil and finasteride are proven for hair growth, herbal remedies show promise, but more research is needed to confirm their effectiveness.

Steroid sex hormones activate matriptase in prostate cancer cells but not in breast cancer cells.

People with alopecia are at higher risk for heart disease and have more heart-related risk factors.

Eclipta prostrata has many traditional uses and health benefits, but more research is needed to understand how it works and ensure it's safe.

Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.

17α-estradiol is a safe estrogen that might protect the brain and doesn't cause feminization, needing more research for treating brain diseases.

Normal levels of DHT can reduce belly fat and increase muscle, but too much can lead to hair loss, prostate issues, and possibly heart disease.

Mild essential fatty acid deficiency can cause health issues and is worsened by low-fat diets.

Premature hair graying may be a sign of increased risk for heart disease, indicating biological age is more important than actual age.

Pumpkin seed oil may improve prostate health, bladder control, and hair growth in men.