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Testosterone's muscle-building effects do not require its conversion to DHT.

Insulin sensitizers may slightly reduce hirsutism but are less effective than other treatments.

The update highlights that non-classic congenital adrenal hyperplasia is common in women with excess male hormones, requires specific hormone tests for diagnosis, and has various treatment options depending on age and symptoms.

Overexpressing Dsg3 in mice skin causes excessive cell growth and abnormal skin development.

People with alopecia areata often have other health issues like skin diseases, metabolic syndrome, stomach infections, lupus, anemia, thyroid problems, mental health issues, vitamin D deficiency, and hearing and eye problems.

Alpha-hydroxy acids, like glycolic acid, safely improve skin issues and work on all skin types.

An imbalanced gut and lack of biotin can cause hair loss in mice.

Animal models have helped understand hair loss from alopecia areata and find new treatments.

Hormonal treatments can help with acne, especially in women, by lowering androgen levels or blocking their effects.

Liver transplantation is a viable option for children with propionic acidemia, improving quality of life and diet, but does not remove all risks and long-term brain outcomes are uncertain.

Hormones, especially androgens, play a key role in acne, which can be a symptom of systemic diseases like PCOS and may require targeted treatment.

Polycystic ovarian shape is a genetic sign of PCOS and its hormonal and metabolic features can be inherited.

PCOS affects women's health by increasing the risk of diabetes, heart disease, and reproductive issues.

FFA's causes may include environmental triggers and genetic factors.

Advanced nanocarrier and microneedle drug delivery methods are more effective, safer, and less invasive for treating skin diseases.

Some parents have a mild form of congenital adrenal hyperplasia without symptoms, and they usually don't need treatment.

Genetic screening is crucial for accurately diagnosing APS-1 due to its varied symptoms.

There are still challenges in diagnosing and treating chronic skin diseases, but there is hope for future improvements.

The article explains the genetic causes and symptoms of various hair disorders and highlights the need for more research to find treatments.

Graft-versus-host disease is a complication where donor immune cells attack the recipient's body, often affecting the skin, liver, and gastrointestinal tract.

Hair loss can indicate underlying systemic diseases and addressing these can sometimes reverse the hair loss.

Acne severity is linked to higher levels of certain androgenic hormones, even when those levels are within the normal range.

The document suggests treating individuals with nonclassic congenital adrenal hyperplasia who show symptoms, especially those related to excess male hormones.

Androgen conjugates might be better indicators of skin sensitivity to hormones in women with excessive hair growth.

The document concludes that recognizing and properly diagnosing lipodystrophy syndromes is crucial for effective management and treatment.

Androgens like testosterone affect hair growth and oil production differently across body parts and individuals.

Excessive hair growth in women often has no known cause and is not linked to race or other hormonal symptoms.

Use "female pattern hair loss" term, assess androgen excess, treat with minoxidil and other medications if needed.

The document concludes with guidance for doctors on diagnosing and treating hirsutism effectively and safely.

The document concludes that Nonclassic Congenital Adrenal Hyperplasia requires personalized treatment plans to manage symptoms and fertility, with glucocorticoids being a common therapy.