January 2023 in “Skin appendage disorders” This study's review of existing research found insufficient data to determine the impact of skin type on the effectiveness of low-light laser therapy for hair growth in androgenetic alopecia, with a notable lack of data on darker skin types.
June 2021 in “Journal of Cosmetic Dermatology” Laser treatment shows promise for hair growth, but needs further research.
90 citations
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February 2000 in “Dermatologic Surgery” This study concluded that the long-pulsed alexandrite laser is safe for hair removal in patients with Fitzpatrick skin types IV-VI, with complications occurring in only 2% of cases.
21 citations
,
January 2007 in “Journal of Drugs in Dermatology” This study found that the 3-msec alexandrite laser effectively reduced unwanted, pigmented hair in individuals with skin types IV and V, but was less safe in those with skin type VI.
10 citations
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January 2010 in “Indian journal of dermatology, venereology, and leprology” This study found that long pulsed Nd: YAG laser is a safe and effective method for hair reduction in individuals with skin types IV and V, with significant improvements observed over six sessions.
9 citations
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May 2005 in “Facial plastic surgery” This article reviews safe and effective hair removal options for dark-skinned patients and reports no new clinical results.
September 2022 in “Journal of The American Academy of Dermatology” This study found insufficient data to determine the effect of skin type on laser-induced hair growth for androgenic alopecia, with only one study suggesting a potential positive effect for darker skin types.
139 citations
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December 1998 in “The journal of investigative dermatology/Journal of investigative dermatology” This study identified a new type II cytokeratin, named K6hf, exclusively expressed in the companion layer of the human hair follicle, distinguishing it from other keratins and suggesting a unique biochemical role.
This study introduced a new laser-only method called EKA for acne treatment, which is reported to be safe, painless, and heat-free, showing promising results for both acne and scar repair in initial sessions without combining with LED light.
In this study, collagen type I, skin fibroblasts, and macrophages did not show remarkable changes in androgenic alopecia patients' scalp tissues after treatment with 1550 nm fractional Er:Glass laser, despite improved hair regrowth.
60 citations
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December 2003 in “Journal of Investigative Dermatology” This study found that keratin 6hf, a type II keratin, is expressed in specific regions of mouse and human hair and suggests potential interactions with keratin 17, impacting hair development and associated disorders.
October 2025 in “International Journal of Research in Dermatology” This review highlights the benefits of long-pulsed Nd:YAG lasers for hair removal in individuals with Fitzpatrick skin types IV-VI, offering deeper follicular targeting with reduced melanin interaction, and examines emerging technologies like radiofrequency and RF microneedling for safe treatment options in skin of color.
January 2025 in “Dermatologic Therapy” In this study, treatment with fractional CO2 laser combined with recombinant humanized type III collagen led to significantly better improvements in atrophic acne scars compared to laser treatment with saline, attributed to collagen upregulation and MAPK pathway activation in human dermal fibroblasts.
April 2024 in “Journal of dermatology research reviews & reports” This clinical trial found that combining 678 nm helmet-type low-level laser therapy with topical minoxidil 5% significantly increased hair density and patient satisfaction in men with androgenetic alopecia, compared to using minoxidil alone. Both treatments were well tolerated.
October 2023 in “Skin research and technology” This study evaluated the effectiveness of a 675 nm laser device on facial acne scars in patients with darker skin types, finding that 67% reported excellent improvement and 33% reported good improvement, with significant enhancements in skin texture and appearance after five treatments.
April 2023 in “Journal of Investigative Dermatology” This study found variation in erythema induction across skin types, suggesting different SSR dose responses and highlighting a potential model for tailoring anti-inflammatory treatments.
May 2026 in “Journal of Clinical Oncology” In this study, patients with advanced cancers reported significant quality of life impacts from second-line therapies, including gastrointestinal and neurological side effects, emotional distress, and social isolation, yet remained motivated to continue treatment for survival and personal connections.
28 citations
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January 2000 in “Dermatologic Therapy” This review discusses laser therapy for revising scars and stretch marks and reports no new clinical results or trials.
14 citations
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May 2011 in “Facial Plastic Surgery Clinics of North America” This review discusses the use of laser and intense light sources for hair removal and reports no new clinical results; the authors highlight the potential for aesthetic medicine to include these technologies.
4 citations
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June 2025 in “Journal of Cosmetic Dermatology” This study found that a high-power triple-wavelength diode laser effectively and safely treated facial hirsutism and follicular disorders in individuals with darker skin tones, showing significant hair reduction without adverse events.
294 citations
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August 1999 in “Journal of the American Academy of Dermatology” This study observed that the majority of side effects from laser-assisted hair removal were associated with ruby and alexandrite lasers, particularly in patients with tanned or darker skin types.
207 citations
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January 2011 in “Dermatologic Therapy” This article discusses the factors involved in optimizing laser hair removal, emphasizing patient selection, laser safety, and understanding laser–tissue interactions, but presents no new clinical findings.
68 citations
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January 2012 in “Lasers in surgery and medicine” This study found that combining microdermabrasion, a topical regimen, and low-fluence QS Nd:YAG laser treatment effectively cleared melasma in women, with 81% of participants achieving over 75% clearance and minimal side effects.
59 citations
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September 2011 in “Lasers in Medical Science” This study concluded that the 800-nm diode laser is effective in enhancing skin structure and collagen expression via the TGF-β/Smad pathway, suggesting potential for non-ablative rejuvenation.
35 citations
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October 2003 in “Dermatologic clinics” This article discusses the lack of national credentialing for laser therapy practitioners and emphasizes the need for rigorous self-assessment and expertise, particularly when treating patients with darker skin, without presenting new research results.
21 citations
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April 2019 in “Journal of cosmetic and laser therapy” This review examines the devices, mechanisms, risks, side effects, and regulatory differences in laser hair removal, particularly highlighting the lack of regulation in South Africa and its implications for patient safety.
21 citations
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January 2019 in “Lasers in Medical Science” This review found that low-level laser therapy significantly increased hair density in adults with androgenic alopecia compared to sham treatments, with greater effects observed at lower treatment frequencies.
16 citations
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April 2020 in “Dermatology practical & conceptual” This article reviews the use of laser and light-based devices for hair removal, highlighting their effectiveness in significantly reducing hair growth in individuals with fair skin and dark hair, and suggests that photoepilation offers advantages over traditional hair removal methods.
15 citations
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August 2011 in “Lasers in medical science” This study reported that a single treatment with a short-pulsed 755-nm alexandrite laser effectively treated trichostasis spinulosa in patients with skin types II to V, providing rapid results with minimal pain and no recurrence during a 3-month follow-up.
14 citations
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March 2012 in “Lasers in Surgery and Medicine” This study concluded that low-level fluence 810 nm diode laser therapy was generally well tolerated, safe, and effective for long-term hair reduction in a small sample of patients with various skin types.