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This review discusses the use of laser and flashlamp technology for unwanted hair removal and reports no new clinical results, highlighting challenges with light-colored hair and treatment safety for darker skin tones.

This literature review reports that laser-assisted hair removal may improve psychological well-being in women with PCOS, emphasizing its effectiveness and safety when conducted by trained professionals.

This study reviewed preclinical and clinical research and found that AFL-assisted topical drug delivery is considered safe and effective, enhancing drug efficacy, reducing treatment time and pain, and improving cosmetic and safety outcomes, but larger clinical trials are needed to confirm these benefits.

This study reviewed the effectiveness of long pulse 1,064-nm Nd:YAG laser treatments for leg veins, hair removal, and skin rejuvenation, highlighting its safety, particularly for darker skin types, due to reduced pigmentary side effect risks.

This study found that combining ultrapulsed fractional CO2 laser with bovine basic fibroblast growth factor significantly improved acne scars more effectively and safely compared to laser therapy alone.

This literature review suggests that fractional laser therapies may positively impact hair regrowth in androgenic alopecia, though current evidence is mostly limited to small studies and case reports, highlighting a need for more comprehensive randomized controlled trials to confirm their efficacy and safety.

This study found that while both professional and home-use lasers effectively reduced axillary hair, the professional Diode laser was significantly more effective, achieving 85-88% reduction compared to 46-52% with the home-use laser, which still offers some safety for users.

This review highlights recent advances in laser treatments for skin disorders, including the optimization of vascular lesion treatment and improved safety for hair removal, but reports no new results.

The studies reviewed found favorable treatment outcomes for hypopigmented scars using PGF2α agonists with no adverse events reported. However, the authors highlight the need for larger randomized controlled trials to better understand their effectiveness and long-term safety.

Among individuals with skin types II and III, this study found the 755 nm laser more effective for axillary hair removal than the dual-wavelength laser, with a better safety profile and enduring results up to 12 months.

This narrative review explores contraindications for fractional CO2 laser treatment of aesthetic disorders, highlighting conditions such as pigmentary disorders, active skin conditions, photosensitivity, and recent isotretinoin use, emphasizing the importance of careful patient selection to minimize risks and enhance safety and effectiveness.

In this pilot study, researchers observed that low-intensity laser radiation at 445±40 nm increased the temperature of gingival tissues in Wistar rats by 8.37°C without exceeding the safety threshold, suggesting potential for clinical trials.

This study used advanced optical imaging techniques to investigate nanoparticle and dye penetration in human skin, finding that nanoparticles mainly resided in the stratum corneum and accumulated in skin folds and hair follicles, while highlighting that sunscreen-based nanoparticles appear unlikely to pose safety concerns.

In this randomized, double-blind trial, researchers observed that low-level laser therapy led to significantly greater hair regrowth on treated areas compared to a sham treatment in patients with androgenetic alopecia over 24 weeks, suggesting it as a potentially effective and safe option.

This review examines the devices, mechanisms, risks, side effects, and regulatory differences in laser hair removal, particularly highlighting the lack of regulation in South Africa and its implications for patient safety.

In this case study, a 39-year-old Japanese woman with severe alopecia areata demonstrated complete hair regrowth after one year using a combination of 0.5% delgocitinib ointment and excimer laser, suggesting potential efficacy and safety compared to conventional treatments.

This study found that thulium laser therapy significantly improved hair regrowth and patient satisfaction in individuals with androgenic alopecia, demonstrating safety and effectiveness with no reported adverse events during short-term evaluation.

The authors concluded that combining fractional lasers with topical therapy may be a promising and effective approach for treating androgenetic alopecia, offering high safety and tolerability.

This study determined in-vivo skin damage thresholds for 1319-nm laser exposure in pigs, and the findings may enhance understanding of thermal damage mechanisms and inform laser safety standards.

In this study, Nd:YAG picosecond lasers using fractional micro-lens array were found to have a comparable effect to ablative fractional Er:YAG lasers in treating atrophic acne scars, with better safety profiles but slightly less patient satisfaction.

In this review, microneedling and platelet-rich plasma were identified as safe and effective cosmetic procedures for diverse skin types, especially among individuals with skin of color, due to their lower risk of postinflammatory hyperpigmentation and faster recovery compared to laser treatments.

This study reported that the 1565 nm non-ablative fractional laser treatment significantly improved various hair growth indices in patients with androgenetic alopecia compared to 5% minoxidil, demonstrating its superior clinical efficacy and safety for treating this condition.

This study used a multi-layer in silico framework to evaluate Korean herbal compounds for androgenetic alopecia, identifying Biochanin A, Saponin Re, and Emodin as potential topical candidates with distinct safety and affinity profiles, although these findings remain purely computational without experimental validation.

This study observed that 5% minoxidil milky lotion increased hair density more than the standard solution at 8 weeks in males with androgenetic alopecia, but their efficacy was similar at later visits.

This study concluded that both low and incremental radiant exposures of diode lasers produced similar hair reduction and patient satisfaction, but low radiant exposure was less painful and better tolerated.

This study found that the long-pulsed alexandrite laser effectively reduced hair growth with varying efficacy depending on the pulse duration, anatomic location, and number of treatments, without causing permanent adverse effects in skin types I–III.

This study found that combining microdermabrasion, a topical regimen, and low-fluence QS Nd:YAG laser treatment effectively cleared melasma in women, with 81% of participants achieving over 75% clearance and minimal side effects.

This study found that the LightSheer Diode EP Laser System significantly reduced hair growth among women with hirsutism, with side effects disappearing within three days and no long-term skin pigmentation issues observed.

In this study, the Avalanche brushing protocol demonstrated similar hair reduction effectiveness to the stamping method, but with significantly lower discomfort reported by patients, suggesting it may be preferable for individuals with sensitive skin or dense hair in early treatment sessions.

Follow these guidelines to safely and effectively use energy-based devices in aesthetic treatments.