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The Multi-Organ-Chip improves the growth and quality of skin and hair in the lab, potentially replacing animal testing.

PGD2 stops hair growth and is higher in bald men with AGA.

Male and female bodies respond differently to stress, influenced by hormones and development stages, with implications for stress-related diseases.

Alopecia areata is likely an autoimmune disease with unclear triggers, involving various immune cells and molecules, and currently has no cure.

AA-PRP injections effectively increase hair count and thickness for male pattern hair loss.

Capsaicin, found in chili peppers, can slow down hair growth by affecting skin cells and hair follicles.

Scientists made working salivary glands in mice using bioengineered cells, which could help treat dry mouth.

Omeprazole effectively treats severe acid reflux in children for short-term use, but long-term safety needs more research.

Early diagnosis and individualized treatment improve outcomes for Congenital Adrenal Hyperplasia.

Nanoparticles improve drug delivery through the skin but more research is needed on their long-term effects and skin penetration challenges.

Effective treatments for male pattern baldness include oral finasteride and topical minoxidil, while topical minoxidil is best for female pattern baldness.

Young adults have about 230,000 tactile nerve fibers, decreasing 5-8% per decade with age.

The document concludes that adenosine receptor agonists have potential for treating various conditions, but only a few are approved due to challenges like side effects and the need for selective activation.

Male hormones affect COVID-19 severity and certain drugs targeting these hormones could help reduce the risk.

The niche environment controls stem cell behavior and plasticity, which is important for tissue health and repair.

Exosomes could potentially enhance tissue repair and regeneration with lower rejection risk and easier production than live cell therapies.

Low doses of some substances can be beneficial, while high doses can be harmful or toxic.

Cepharanthine is a well-tolerated drug with multiple medical uses, including anti-inflammatory and anti-cancer properties.

Stem cell plasticity is crucial for wound healing but can also contribute to cancer development.

New targets for making and using brain-synthesized steroids could lead to better treatments for brain disorders and alcoholism.

The telogen phase of hair growth is active and important for preparing hair follicles for regeneration, not just a resting stage.

Estrogens help reduce skin aging, and SERMs might offer similar benefits without the risks of hormone therapy.

Vitamin D has potential benefits for cancer prevention, heart health, diabetes, obesity, muscle function, skin health, and immune function, but clinical results are mixed and more research is needed.

The document concludes that while significant progress has been made in understanding skin biology and stem cells, more research is needed to fully understand their interactions with their environment.

Macrophages help regrow hair by activating stem cells using AKT/β-catenin and TNF.

Male pattern hair loss is genetic and influenced by hormones, with treatments like minoxidil and surgery available.

Hair loss in men treated best with early medication or transplant, new treatments researched.

No treatment fully prevents hair loss from chemotherapy yet.

Nanoparticles can improve skin treatments by better targeting hair follicles, but more research is needed for advancement.

Mice studies show that Protein Phosphatase 2A is crucial for cell growth, development, and disease prevention.