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    Glossary Laser Capture Microdissection

    technique using a laser to isolate specific cells from tissue

    Laser Capture Microdissection (LCM) is a technique used to precisely isolate specific cells or regions from a tissue sample using a laser. This allows researchers to study the genetic material, proteins, or other cellular components of the selected cells without contamination from surrounding tissues, making it particularly useful in fields like cancer research and pathology.

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    1. Laser Capture Microdissection Reveals Transcriptional Abnormalities in Alopecia Areata before, during, and after Active Hair Loss Journal of Investigative Dermatology · 2015 · 16 citations
    2. Folliculotropic mycosis fungoides with central nervous system involvement: Demonstration of tumor clonality in intrafollicular T cells using laser capture microdissection Journal of the American Academy of Dermatology · 2003 · 14 citations
    3. Laser capture microdissection as a method for investigating the human hair follicle microbiome reveals region-specific differences in the bacteriome profile BMC Research Notes · 2023 · 8 citations
    4. 551 Combining Laser Capture Microdissection and RNAseq Analysis to Generate a Human Anagen Hair Follicle Transcriptome Atlas 2022
    5. 731 Generation of a laser capture microdissection and RNAseq-based human anagen hair follicle transcriptome atlas 2022
    6. Advances in the Study of Stem-Cell-Enriched Hair Follicle Bulge Cells: A Review Featuring Characterization and Isolation of Human Bulge Cells Dermatology · 2007 · 16 citations
    7. Condylomata acuminata of HIV-positive men may harbour focal areas of dysplasia: relevant implications for the management of human papillomavirus-induced disease in high-risk patients British Journal of Dermatology · 2016 · 3 citations
    8. 555 Dermal single-cell atlas: a novel tool to explore fibroblast heterogeneity Journal of Investigative Dermatology · 2022
    9. Characterization and isolation of stem cell–enriched human hair follicle bulge cells ˜The œYear book of dermatology · 2007
    10. Gene expression profiling gets to the root of human hair follicle stem cells 2005 · 92 citations
    11. Exosomes Secreted from Adipose-Derived Stem Cells Are a Potential Treatment Agent for Immune-Mediated Alopecia Journal of immunology research · 2022 · 6 citations
    12. Expansion of Hair Follicle Stem Cells Sticking to Isolated Sebaceous Glands to Generate in Vivo Epidermal Structures Cell Transplantation · 2016 · 10 citations
    13. Lineage Analysis of Epidermal Stem Cells Cold Spring Harbor Perspectives in Medicine · 2014 · 57 citations
    14. Trans‐species hair growth induction by human hair follicle dermal papillae Experimental Dermatology · 2001 · 66 citations
    15. Defining the identity of mouse embryonic dermal fibroblasts Genesis · 2016 · 21 citations
    16. Gene Expression Profiling of the Intact Dermal Sheath Cup of Human Hair Follicles Acta dermato-venereologica · 2018 · 11 citations
    17. Human epithelial hair follicle stem cells and their progeny: Current state of knowledge, the widening gap in translational research and future challenges BioEssays · 2014 · 106 citations
    18. Hair Follicle: A Novel Source of Multipotent Stem Cells for Tissue Engineering and Regenerative Medicine Tissue Engineering Part B-reviews · 2012 · 65 citations
    19. Collagen-Heparin-FGF2-VEGF Scaffolds Induce a Regenerative Gene Expression Profile in a Fetal Sheep Wound Model Tissue Engineering and Regenerative Medicine · 2024 · 9 citations
    20. Hair, Cutaneous Homeostasis and Stem Cell Functions Journal of Investigative Dermatology · 2014
    21. Study of Skin Expression of MicroRNA-146a in Patients with Alopacia Areata Benha Journal of Applied Sciences · 2018
    22. Mapping cell dynamics in human ex vivo hair follicles suggests pulling mechanism of hair growth Nature Communications · 2025
    23. Alterations in Hair Follicle Morphology and Hair Shaft Production After Follicular Unit Transplantation The American Journal of Dermatopathology · 2016 · 8 citations
    24. Tissue engineering of human hair follicles using a biomimetic developmental approach Nature Communications · 2018 · 184 citations
    25. Hair Follicle Immune Privilege Revisited: The Key to Alopecia Areata Management 2017 · 102 citations
    26. Sex steroid synthesis in human skin in situ: The roles of aromatase and steroidogenic acute regulatory protein in the homeostasis of human skin Molecular and Cellular Endocrinology · 2012 · 46 citations
    27. Mechanical Stretch Upregulates SDF-1α in Skin Tissue and Induces Migration of Circulating Bone Marrow-Derived Stem Cells into the Expanded Skin Stem Cells · 2013 · 43 citations
    28. DMBA/TPA Treatment Is Necessary for BCC Formation from Patched Deficient Epidermal Cells in Ptch flox/flox CD4Cre +/− Mice Journal of Investigative Dermatology · 2014 · 11 citations
    29. Cell Density-Dependent Upregulation of PDCD4 in Keratinocytes and Its Implications for Epidermal Homeostasis and Repair International Journal of Molecular Sciences · 2015 · 10 citations
    30. Sample collecting methods for bacterial community structure analysis of scalp hair: non-invasive swabbing versus intrusive hair shaft cutting Scientific Reports · 2024 · 1 citations