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The skin is a complex barrier for drug penetration, but understanding its structure and interactions can improve drug delivery methods.

Pregnancy can cause various skin changes and diseases, with PUPPP being the most common skin condition specific to pregnancy.

Metformin helps manage polycystic ovary syndrome by improving insulin resistance and ovulation, but more research is needed on its full effects.

Male and female bodies respond differently to stress, influenced by hormones and development stages, with implications for stress-related diseases.

High levels of male hormones, insulin resistance, and obesity are closely linked and worsen polycystic ovary syndrome, but more research is needed to improve treatments.

Targeted cancer therapies often cause serious skin problems that need careful management.

Women with PCOS are more likely to have impaired glucose tolerance and type 2 diabetes, especially if they are Asian or obese.

Opioid painkillers can cause many side effects, including breathing problems and addiction, but are generally considered safe when used properly.

The PDGF/PDGFR pathway is a potential drug target with mixed success in treating various diseases, including some cancers and fibrosis.

Trichoscopy is a useful tool for diagnosing different hair and scalp diseases by their unique visual features.

Toxic Shock Syndrome mainly affects menstruating women, can recur, and is linked to staph bacteria, with rapid treatment being crucial.

Women look young for their age due to larger lips, less sun damage, and genes that prevent gray hair and wrinkles.

Chemotherapy can cause skin problems like hair loss, mouth sores, and skin darkening, and recognizing these can affect treatment decisions.

Epidermal stem cells are diverse and vary in activity, playing key roles in skin maintenance and repair.

Mostly postmenopausal Caucasian women get Frontal Fibrosing Alopecia, which often includes eyebrow loss and has limited treatment success.

Hair follicle stem cells are key for hair and skin regeneration, can be reprogrammed, and have potential therapeutic uses, but also carry a risk of cancer.

Low iron levels may be linked to some types of hair loss in women.

Latanoprost can make eyelashes longer, thicker, and darker.

Some skin medications are safe during pregnancy and breastfeeding, but others can harm the baby and should be avoided.

DrugNet effectively identifies new uses for existing drugs and may save resources in drug development.

Caffeine in cosmetics may reduce cellulite, protect skin, and stimulate hair growth, but more research is needed on its use and effects.

Silver can help prevent and treat infections but its effectiveness varies and should be weighed against costs and side effects.

Stem cell self-renewal is complex and needs more research for full understanding.

The dermal papilla is crucial for hair growth and health, and understanding it could lead to new hair loss treatments.

Alopecia areata is an autoimmune disease causing patchy hair loss, often with other autoimmune disorders, but its exact causes are unknown.

Most people with systemic lupus erythematosus have skin problems, and skin symptoms are often the first sign of the disease.

Keratinocytes help heal skin wounds by interacting with immune cells and producing substances that kill pathogens.

Postpartum depression is linked to changes in brain chemicals, inflammation, stress, and certain genes, and can potentially be identified by markers like specific steroids, serotonin levels, and vitamin D levels.

Modern science supports the use of some Ayurvedic plants for health, as ancient practices suggested.

Masculine facial features may not reliably indicate heritable health, and more research is needed.