January 2026 in “International Journal of Science and Research Methodology” This review explored the therapeutic potential of Bhangra (Eclipta alba) for treating premature greying of hair, noting the plant's melanogenic, antioxidant, and revitalizing properties, but highlighted the need for further research to scientifically support its effectiveness.
October 2025 in “Journal of Drug Delivery and Therapeutics” In this review, the researchers compared the traditional use of Senna Makki in Unani medicine for various ailments to modern pharmacological evidence, endorsing its role as a laxative but indicating further research is needed for its efficacy in other therapeutic areas.
In this review, researchers evaluated 111 studies on the biological activities and phytochemical components of the plant Tridax procumbens, emphasizing its ethnobotanical potential and the need for more research to understand its therapeutic benefits, especially in its native tropical regions.
January 2025 in “International journal of Indian medicine” This review discusses nine Ayurvedic medicinal herbs listed in the Dhanvantari Nighantu as beneficial for hair, detailing their properties like promoting hair growth, enhancing hair thickness, and maintaining dark hair color, alongside supporting research on these effects.
This review of Lawsonia inermis L., or henna, details its bioactive compounds and historical uses in Unani medicine, including treatment for various conditions like ulcers and jaundice, while highlighting its potential for wound healing, hepatoprotective, and other effects, though further research is needed.
July 2023 in “Research Square (Research Square)” This study developed finite element models to examine skin's biomechanical properties, finding that structural heterogeneities like Rete ridges and hair follicles create distinct stress and strain patterns that may influence mechanosensation and skin integrity.
March 2022 in “Journal of Survey in Fisheries Sciences” This review discusses the diverse phytochemical constituents and medicinal applications of Asteraceae family plants, noting their significance in traditional and modern medicine, but provides no new clinical results.
December 2020 in “International Journal of Biosciences (IJB)” This review discusses a traditional medicinal plant used in various holistic health systems and reports its potential antitumor activity, but no new clinical results are provided.
January 2012 in “Human health handbooks” This article explores the role of ethno-medicinal plants in hair growth and loss treatments but reports no new clinical findings, highlighting Ayurveda's long-standing use in addressing hair-related issues.
139 citations
,
October 1999 in “Environmental Health Perspectives” This article reviews the scientific exploration of Ayurvedic medicinal plants and discusses their modern applications, such as a drug developed from Commiphora wightti for lipid disorders, without reporting new clinical findings.
143 citations
,
April 2018 in “Electronic physician” This article discusses the potential benefits of safflower in traditional Persian medicine for various conditions and highlights the need for comprehensive phytochemical research, without reporting new clinical results.
36 citations
,
October 1996 in “Dermatologic Clinics” In this study, a methanol extract of Eclipta alba was found to have dose-dependent hair growth-promoting activity in C57BL6 mice.
11 citations
,
January 2024 in “Indian Journal of Pharmaceutical Sciences” This review summarizes the enhanced absorption and bioavailability of phytosome delivery systems, which combine herbal extracts with phospholipids to improve therapeutic potential, and provides an updated overview of their development, commercial availability, and patented technologies.
1 citations
,
September 2024 in “Scientific Reports” This study observed that bacterial communities on scalp hair collected through non-invasive swabbing showed similar diversity and composition to those obtained by cutting or removing hair, suggesting that swabbing is an effective method for microbiome analysis on hair.
1 citations
,
January 2017 in “Social Science Research Network” This paper suggests that to better protect traditional and indigenous knowledge, TKDL should expand its database or establish a separate confidential resource for indigenous, tribal, and nomadic communities.
May 2022 in “Journal of pharmacognosy and phytochemistry” This study carried out a detailed pharmacognostic and phytochemical analysis of Sphagneticola calendulacea leaves, which may help authenticate this plant used in treating inflammation and alopecia.
May 2026 in “Repository of the University of Ljubljana (University of Ljubljana)” This study analyzed the composition and cost of 50 cosmetic body scrubs for keratosis pilaris, finding that chemical exfoliants with glycolic acid may reduce symptoms by enhancing skin shedding and reducing water loss, but further clinical studies are needed to confirm their effectiveness.
August 2017 in “Indian journal of history of science” This review discusses the Strīvilāsa, an Ayurvedic manuscript on female health and cosmetic procedures, but reports no clinical results; the authors emphasize its potential significance for Ayurvedic obstetrics and gynecology research.
This study identified the TALE homeodomain transcription factor Meis2 as a crucial regulator for the maturation and end-organ innervation of certain mechanoreceptors in mice, with its absence leading to altered sensory neuron structure and impaired touch sensitivity.
140 citations
,
February 2014 in “Neuron” This study found that the opioid system, particularly via the delta opioid receptor, broadly regulates cutaneous mechanosensation, including touch, and suggests targeting this receptor could alleviate injury-induced mechanical hypersensitivity.
1 citations
,
April 2022 in “Journal of The American Academy of Dermatology” This study found that decreased pressure sensitivity and 2-point discrimination at the scalp's vertex were significantly associated with androgenetic alopecia in men.
13 citations
,
August 2005 in “Journal of Investigative Dermatology Symposium Proceedings” This study describes a genetic mutation in the desmoglein 4 gene linked to localized autosomal recessive hypotrichosis in Pakistani families, showing similarities to animal models with similar hair loss conditions.
In this study, rat vibrissa follicles transplanted into mice demonstrated survival, partial sympathetic nerve reinnervation, and increased norepinephrine levels 37 days post-implantation, suggesting potential for hair growth despite not returning to normal nerve function.
97 citations
,
March 2006 in “Journal of Investigative Dermatology” This study identified four novel DSG4 mutations associated with monilethrix in 12 Jewish families, suggesting a recessive inheritance pattern and broader prevalence of DSG4-related hair disorders than previously recognized.
44 citations
,
August 2004 in “Journal of Investigative Dermatology” A gene deletion in DSG4 causes sparse hair in some Pakistani families.
33 citations
,
October 2005 in “Journal of Investigative Dermatology” A specific gene mutation causes sparse, brittle hair in a family.
19 citations
,
February 2016 in “Journal of Biological Chemistry” In this study, researchers observed that knocking out KCNQ3 in mice increased firing frequencies in response to stimuli, particularly at slow mechanical indentation velocities, indicating a role in mechanosensory neuron sensitivity.
7 citations
,
July 2025 in “The Journal of Physiology” This study found that human C-tactile afferents respond to hair deflection, suggesting a functionally relevant anatomical relationship to hair follicles similar to that observed in mice.
4 citations
,
June 2025 in “Molecules” This review evaluates traditional uses, phytochemical profiles, and pharmacological activities of Mediterranean Erica species, revealing the wide range of bioactive compounds and highlighting their antioxidant, anti-inflammatory, and antimicrobial activities. Further studies are suggested to fully understand their medicinal potential.
1 citations
,
May 2025 in “Preprints.org” This review evaluates the traditional uses, phytochemical profiles, and pharmacological potential of Mediterranean Erica species and reports no new clinical results, highlighting the need for further studies.