January 2004 in “Kölner Universitäts PublikationsServer (Universität zu Köln)” This study suggests that CD151-integrin complexes inhibit epithelial cell migration, and that disruption of these complexes enhances migration, regulated by Rho GTPase activation differences on distinct laminins.
2 citations
,
October 2024 in “Journal of Cosmetic Dermatology” This study highlights that chemicals used in brow lamination, like ammonium thioglycolate and thioglycolic acid, may cause skin irritation and other systemic issues, suggesting a need for further investigation and regulatory measures.
6 citations
,
May 2021 in “Stem Cell Reviews and Reports” This study identified and characterized progenitor cells from equine feet that may play a role in the pathogenesis and recovery of laminitis, suggesting potential therapeutic targets for treatment.
1 citations
,
June 2025 in “Journal of Veterinary Internal Medicine” In this case study, a miniature donkey with multisystemic eosinophilic epitheliotropic disease was euthanized due to laminitis despite treatment for pruritus, inappetence, hypertriglyceridemia, and alopecia.
This source explains that Equine Cushing’s disease, or PPID, in horses is due to the degeneration of brain cells producing dopamine, leading to elevated cortisol levels and characteristic symptoms; it outlines diagnosis methods and emphasizes life-long pergolide treatment to manage the condition.
238 citations
,
October 1994 in “Current opinion in genetics & development” This article reviews the role of epidermal proteins and regulatory mechanisms in skin diseases, emphasizing recent insights but reports no new experimental results.
9 citations
,
September 2019 in “PLoS ONE” This study demonstrated that keratin K124 is specific to equine hoof lamellar tissue and established monoclonal antibodies that can specifically recognize K124 without cross-reacting with other tissues.
This study found that hoof progenitor cells from fresh equine tissue have multilineage differentiation capabilities, offering insights for future progenitor cell-based hoof and dermal-epidermal tissue engineering.
June 2026 in “Experimental Dermatology” This review explores the roles of laminin-332 in skin function, highlighting its involvement in epidermal cohesion, stem cell maintenance, wound healing, and potential in genetic therapies for junctional epidermolysis bullosa.
October 2024 in “Developmental Dynamics” This paper highlights advances in Developmental Dynamics, noting how epoa-deficient zebrafish can model Diamond-Blackfan anemia like disorders for drug screening, Alx4 mouse models offer insights into craniofacial development, and mTORC1 signaling is crucial for retinal development.
33 citations
,
April 2011 in “Journal of Veterinary Internal Medicine” This study found that inhaled fluticasone for 11 months did not adversely affect the immune function or response to vaccination in horses with heaves.
November 2020 in “Journal of The American Academy of Dermatology” This study reported that using plain bottles instead of commercial kits for extracting platelet-rich plasma may be an effective method for treating hair loss.
102 citations
,
August 2008 in “Genes & Development” This study found that laminin-511 is crucial for hair morphogenesis in mice, as it influences primary cilia formation and dermal papilla maintenance through noggin and sonic hedgehog signaling.
13 citations
,
June 2018 in “Journal of histochemistry and cytochemistry/The journal of histochemistry and cytochemistry” This study found that the expression of laminin-511 and -332 was significantly increased in psoriasis skin lesions and may influence keratinocyte proliferation and apoptosis, suggesting a previously overlooked role in the disease's pathogenesis.
7 citations
,
March 2020 in “PloS one” This study demonstrates that α-parvin is crucial for epidermal morphogenesis and hair follicle development by mediating integrin-dependent adhesion and actin organization in keratinocytes.
5 citations
,
May 2020 in “Life science alliance” This study found that epidermal-specific deletion of integrin α3β1 significantly reduces papilloma formation in a skin carcinogenesis model by modulating HB stem cell behavior and CCN2 expression.
January 2026 in “Materials Horizons” This article promotes professional recognition in science careers but reports no new research findings.
December 2025 in “Doğu Fen Bilimleri Dergisi” In this study, researchers found that the expression of vimentin, desmin, and laminin in rat skin contributes to cell structure and tissue integrity, with varying reactions across different cell types.
This study introduced a rapid rehydration approach for creating customizable, multifunctional hydrogel sensors, enabling precise detection of surface deformations and easy integration of layers, highlighting its potential for standardized and adaptable manufacturing of wearable devices.
September 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” This study describes the use of a genetically engineered mouse model, mTurquoise2-Col4a1, to fluorescently label collagen IV and observe basement membrane dynamics during skin development, revealing its stability and pliability during rapid growth phases.
April 2018 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that in a mouse model of Focal Dermal Hypoplasia, treatment with lithium carbonate improved skin disease symptoms compared to controls, though disease severity varied and posed interpretation challenges.
5 citations
,
December 2005 in “Clinical Techniques in Equine Practice” This review discusses how skin lesions and haircoat changes in adult horses can indicate systemic diseases, emphasizing the need for veterinary evaluation, and reports no new clinical findings.
May 2023 in “Animal Reproduction Update” This article reviews the use of hair cortisol concentration as a biomarker to assess long-term stress in both animals and humans, but it reports no new experimental results.
September 2020 in “Kocatepe Veterinary Journal” This study suggests that equine adipose tissue stem cells may be a promising option for cellular regenerative therapy in equines due to their differentiation capabilities and proliferation potential, but further molecular characterization is needed.
July 2014 in “Elsevier eBooks” The document concludes that various hypersensitivity diseases in horses can be diagnosed and treated with methods like immunotherapy and medication, and early aggressive treatment is crucial for severe diseases like equine cutaneous pythiosis.
60 citations
,
December 2013 in “PLoS ONE” The researchers found that inhibiting soluble epoxide hydrolase, either genetically or pharmacologically, delayed the onset of chemically induced seizures related to GABA antagonism in experimental models.
556 citations
,
September 2008 in “Genes & Development” This review summarizes how genetic studies using conditional β-catenin loss- and gain-of-function mice have advanced understanding of canonical Wnt signaling's role in embryonic development, adult stem cell maintenance, and cancer modeling.
277 citations
,
July 2011 in “Journal of the Dermatology Nurses’ Association” The skin's layers protect, sense, and regulate the body's internal balance, but can be prone to cancer.
262 citations
,
May 2017 in “Nanomedicine” This review examines recent advancements in electrospun nanofibers for wound healing applications, but reports no new experimental results, highlighting their potential in sutures, dressings, and skin regeneration.
130 citations
,
September 2018 in “Cell Reports” This study found that macrophages play a crucial role in nerve regeneration by regulating Schwann cell dynamics and remyelination, with Gas6 identified as a key factor in this process.