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Most drugs fail to reach the market, but understanding their properties and using strategies like early toxicity tests and drug repurposing can help advance their development.

The new gel combining calcipotriene and betamethasone is effective and safe for treating scalp psoriasis.

The document concludes that Hilary Mantel's memoir shows how childhood experiences affect adult health, criticizing modern medicine for ignoring the mental aspects of physical illness.

HDAC6 helps keep ovarian follicles dormant, extending female fertility.

Carboplatin-paclitaxel is preferred for advanced lung cancer due to its balance of affordability and patient well-being.

TLR3 signaling enhances the immunosuppressive properties of human periodontal ligament stem cells.

Cancer rates are increasing in developed countries, with estrogen, aging, low vitamin D3, and HPV infection as common causes.

Eating a balanced diet with specific nutrients can help manage menopause symptoms and prevent related health issues.

The issue concluded that various skin conditions have different effective treatments and factors influencing them.

The document suggests using natural remedies like bloodletting and honey for various health issues but lacks scientific evidence for their effectiveness.

Teak is a durable, termite-resistant wood with medicinal benefits.

Men with Type 2 Diabetes have lower DHT levels, which may affect fertility and lipid profiles.

A woman with alopecia totalis regrew dark hair in bands after using a corticosteroid ointment.

The junction of the inner and outer prepuce with good blood flow is best for vascular pedicle flaps.

Micro-CT helps identify suitable areas for surgical procedures based on blood vessel distribution in hypospadias-affected rats.

Dermoscopy is useful for diagnosing hair loss patterns in dogs.

Several companies launched new hair care ingredients in 2011 to improve conditioning, color retention, combability, and heat protection.

Greater intimacy leads to better self-reported health in couples having infertility treatment.

The meeting presented findings on effective treatments for various pet skin conditions and insights into the immune responses of dogs with atopic dermatitis.

Taking calcium may help elderly with osteoporosis, birth control with levonorgestrel doesn't increase heart attack risk, Salmonella can cause arthritis, a national ethics committee is recommended, and sulfasalazine might help with a hair loss condition.

Beta-blockers and anti-anginal medications have various side effects and interactions that require careful monitoring and individualized treatment.

The document discusses various public health initiatives and societal issues, emphasizing early intervention and support.

Certain circular RNAs are crucial for wool growth and curvature in goats.

Researchers found that certain RNA circles in the brain are linked to disease risk, but their exact role in disease is still unknown.

SOX9 is essential for the development of various organs and hair follicles.

Melatonin improved secondary hair growth in goats but didn't affect primary hair density or litter size.

Vitamin A affects hair loss and immune response in alopecia areata.

Testosterone replacement is recommended for men with low testosterone levels and symptoms of hypogonadism.

Overexpressing Tβ4 in cashmere goats improves hair fiber traits and increases cashmere yield.

Natural volatiles and essential oils have health benefits and can enhance the effects of some medicines, but more research is needed to understand how they work and their possible side effects.