67 citations,
October 2005 in “Annals of Oncology” Fulvestrant is a well-tolerated new treatment for advanced breast cancer that may delay chemotherapy.
53 citations,
October 1984 in “Endocrine reviews” Excessive hair growth in women often has no known cause and is not linked to race or other hormonal symptoms.
33 citations,
February 1999 in “The journal of investigative dermatology/Journal of investigative dermatology” IGF-1 increases whisker growth in transgenic mice.
15 citations,
September 2005 in “The Journal of the American Animal Hospital Association/Journal of the American Animal Hospital Association” Trilostane effectively treated hair loss in Alaskan Malamutes with no adverse effects.
6 citations,
February 2014 in “Actas Dermo-Sifiliográficas” Obesity is linked to skin conditions like acanthosis nigricans and skin tags, which may indicate high insulin levels.
1 citations,
September 2013 in “Elsevier eBooks” Hair ages and thins due to factors like inflammation and stress, and treatments like antioxidants and hormones might improve hair health.
April 2015 in “Andrology” HNG may help prevent the negative effects of chemotherapy on sperm production and white blood cell counts.
May 2002 in “Australasian Journal of Dermatology” Finasteride is effective for male hair loss, teledermatology is accurate and accepted, and cyclosporin helps treat toxic epidermal necrolysis.
Different drugs are used to manage breeding, prevent or end pregnancy, and treat reproductive issues in dogs and cats.
March 2017 in “BJU international” The BJUI supports clinical trials as key for unbiased medical evidence and works to enhance their design, reporting, and discussion.
September 2008 in “Fertility and Sterility” Men and women in infertile couples feel using donor sperm may cause more stress and marital issues than using donor eggs.
September 2008 in “Fertility and Sterility” Exposure to fatty acids significantly increased androgen levels in female dogs, suggesting a link to conditions like insulin resistance and PCOS.
281 citations,
January 2013 in “British Journal of Dermatology” Manage vitiligo with treatments, address emotions, and use camouflage techniques.
202 citations,
August 2007 in “Biomaterials” Artificial skin development has challenges, but new materials and understanding cell behavior could improve tissue repair. Also, certain growth factors and hydrogel technology show promise for advanced skin replacement therapies.
176 citations,
January 2003 in “Journal of Investigative Dermatology” Bone Morphogenetic Proteins (BMPs) help control skin health, hair growth, and color, and could potentially be used to treat skin and hair disorders.
158 citations,
January 2015 in “Artificial Intelligence in Medicine” DrugNet effectively identifies new uses for existing drugs and may save resources in drug development.
152 citations,
December 2007 in “Gender Medicine” Male and female skin differ due to hormones, affecting conditions like hair loss, acne, and skin cancer, and suggesting a need for gender-specific treatments.
147 citations,
November 2020 in “International Journal of Molecular Sciences” Keratinocytes help heal skin wounds by interacting with immune cells and producing substances that kill pathogens.
124 citations,
October 2019 in “Frontiers in Immunology” Janus kinase inhibitors are promising treatments for autoimmune skin diseases like eczema and psoriasis.
92 citations,
August 2017 in “Proceedings of the National Academy of Sciences of the United States of America” Newborn mouse skin cells can grow hair and this process can be recreated in adult cells to potentially help with hair loss.
89 citations,
January 2009 in “Advances in Clinical Chemistry” Fetal skin heals without scarring due to unique cells and processes not present in adult skin healing.
68 citations,
November 2011 in “The American journal of pathology” Abnormal Hedgehog signaling in blood cancers may help tumors grow and resist chemotherapy, suggesting potential for targeted treatments.
66 citations,
December 2018 in “Dermatology” Both ruxolitinib and tofacitinib are effective and safe for treating severe alopecia areata, but relapses are common.
63 citations,
April 2010 in “Development” Compartmentalized organization might be crucial for stem cells to effectively respond to growth or injury.
60 citations,
February 2013 in “Cell reports” The balance between androgen receptor and p53 is crucial for sebaceous gland differentiation.
53 citations,
October 1978 in “Archives of dermatology” Zinc supplements can resolve skin issues caused by zinc deficiency.
51 citations,
January 2004 in “Domestic animal endocrinology” Melatonin implants and long daylight hours alter the timing of hormone release and hair growth in mouflon sheep.
50 citations,
September 2011 in “Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids” Maintaining the right amount of retinoic acid is crucial for healthy hair and skin.
46 citations,
June 2015 in “Fertility and Sterility” Insulin resistance is significantly linked to a higher risk of depression in women with PCOS.
42 citations,
November 2002 in “The American journal of pathology” Distinct β-catenin patterns are linked to cell growth, not cell death, in lung cancer.