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    Glossary Lactic Acid

    organic compound produced in muscles during intense exercise

    Lactic acid, also known as 2-Hydroxypropanoic Acid, is an organic compound produced in muscles during intense exercise when oxygen levels are low, leading to a temporary anaerobic state. It is also found in fermented foods like yogurt and sauerkraut, and is used in various industries, including cosmetics, where it acts as an exfoliant to help remove dead skin cells and improve skin texture.

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    1. Novel Placenta-Derived Liquid Product Suitable for Cosmetic Application Produced by Fermentation and Digestion of Porcine or Equine Placenta Using Lactic Acid Bacterium Enterococcus faecalis PR31 Fermentation · 2024 · 5 citations
    2. Traditional Chinese Medicine Shi-Bi-Man regulates lactic acid metabolism and drives hair follicle stem cell activation to promote hair regeneration Chinese Medicine · 2023 · 1 citations
    3. Lactic Acid Bacteria as Probiotics Improve Bioactive Compounds in Radix Angelica gigas (Danggui) via Solid-State Fermentation Fermentation · 2025 · 1 citations
    4. Topical 15% Lactic Acid Solution Versus Topical Betamethasone Valerate Lotion in the Treatment of Multiple Patchy Alopecia Areata 2024
    5. Topical 15% Lactic Acid Solution versus Topical Betamethasone Valerate lotion in Treatment of Multiple patchy alopecia aerate. 2024
    6. Quantification of Squalene and Lactic Acid in Hair Bulbs with Damaged Sheaths: Are They Metabolic Wastes in Alopecia? Biomedicines · 2023
    7. Natural product Shi-Bi-Man regulates lactic acid metabolism and drives hair follicle stem cell activation to promote hair regeneration Research Square (Research Square) · 2023
    8. Eruptive vellus hair cysts treated with lactic acid: Case report and review of the literature Journal of the American Academy of Dermatology · 2010
    9. Evaluation of lactic acid ferment lysate for the management of oily skin: impact on sebum, hydration, and microbiota Frontiers in Physiology · 2026
    10. Comparison of three different lactic acid bacteria-fermented proteins on RAW 264.7 osteoclast and MC3T3-E1 osteoblast differentiation Scientific reports · 2023
    11. Effect of Hyaluronic Acid and Poly-L-Lactic Acid Dermal Fillers on Collagen Synthesis: An in vitro and in vivo Study Clinical, cosmetic and investigational dermatology · 2020 · 34 citations
    12. Development and ex-vivo skin permeation studies of finasteride–poly(lactic acid-<i>co</i>-glycolic acid) and minoxidil–chitosan nanoparticulate systems Journal of Bioactive and Compatible Polymers · 2020 · 12 citations
    13. Development and characterization of poly(lactic-co-glycolic acid) (PLGA) nanoparticles with finasteride and in vivo evaluation of their efficacy in hair growth Brazilian Journal of Hair Health · 2024
    14. Poly (lactic-co-glycolic acid)-based microneedles for drug delivery across different biological barriers International Journal of Pharmaceutics · 2025
    15. Management of Visible Granulomas Following Periorbital Injection of Poly-L-Lactic Acid Ophthalmic Plastic and Reconstructive Surgery · 2007 · 49 citations
    16. Alopecia Induced by Poly-L-Lactic Acid Injection Cutis · 2024 · 1 citations
    17. Poly-D,L-Lactic Acid Filler Restores Hair Thickness and Shine by Ameliorating Age-Associated Follicular Decline International Journal of Molecular Sciences · 2026
    18. Poly-D,L-Lactic Acid Filler Increases Hair Growth by Modulating Hair Follicular Stem Cells in Aged Skin Cells · 2025
    19. Engineering a skin-mimicking asymmetric poly(L-lactic acid/gelatin bioscaffold for skin repair Materials Technology · 2025
    20. Alopecia secondary to poly-L-lactic acid dermal fillers JAAD Case Reports · 2025
    21. Comparison of MMP1 gene expression and collagen percentage in response to polydioxanone, poly-L-lactic acid and polycaprolactone thread implantation in ageing rat skin Scripta Medica · 2025
    22. Alopecia Induced by Poly-L-Lactic Acid Injection Cutis · 2024
    23. The Current Art Combination of Platelet-Rich Plasma and Poly-D,L-Lactic Acid For Improvement of Deep Nasolabial Folds: A Case Report Zenodo (CERN European Organization for Nuclear Research) · 2022
    24. The Potential Teeth Bleaching and Halitosis Prevention Effects of Pediococcus inopinatus THK-30, a Kimchi-Derived Lactic Acid Bacterium: In Vitro Study Journal of functional biomaterials · 2024
    25. Evaluation of the Effect of NT-3 and Biodegradable Poly-l-lactic Acid Nanofiber Scaffolds on Differentiation of Rat Hair Follicle Stem Cells into Neural Cells In Vitro Journal of Molecular Neuroscience · 2013 · 19 citations
    26. Correction: Traditional Chinese Medicine Shi-Bi-Man regulates lactic acid metabolism and drives hair follicle stem cell activation to promote hair regeneration Chinese Medicine · 2023
    27. Erratum to: Evaluation of the Effect of NT-3 and Biodegradable Poly-L-lactic Acid Nanofiber Scaffolds on Differentiation of Rat Hair Follicle Stem Cells into Neural Cells In Vitro Journal of Molecular Neuroscience · 2016 · 11 citations
    28. The Current Art Combination of Platelet-Rich Plasma and Poly-D,L-Lactic Acid For Improvement of Deep Nasolabial Folds: A Case Report International journal of medical science and clinical research studies · 2022
    29. Mitochondrial DNA 10158T>C mutation in a patient with mitochondrial encephalomyopathy with lactic acidosis, and stroke-like episodes syndrome Medicine · 2020 · 5 citations
    30. A Pilot Study of the Influence of Probiotics on Hair Toxic Element Levels After Long-Term Supplement with Different Lactic Acid Bacteria Strains Journal of probiotics & health · 2018 · 3 citations