21 citations
,
September 2013 in “Journal of circadian rhythms” In this study, heavy nighttime physical exercise delayed the circadian phase of clock gene expression by 2 to 4 hours in a professional fighter, suggesting potential implications for managing circadian disorders.
38 citations
,
November 2018 in “Scientific Reports” This study suggests that chicken and alligator scales evolved independently through convergent evolution rather than sharing a common origin with avian feathers.
This genetic study identified a potential interval for the Marie Unna hypotrichosis gene but found no mutations in the nearby hr gene, suggesting its involvement remains unconfirmed.
November 2016 in “Universiti Putra Malaysia Institutional Repository (Universiti Putra Malaysia)” This study found that Dendrobium sabin flower extracts, especially the methanolic one, demonstrated strong antioxidant and anti-aging properties without significant toxicity, suggesting its potential in treating photo-induced skin aging.
47 citations
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August 2014 in “The Journal of Clinical Endocrinology and Metabolism” This study suggests that variations in PCOS phenotypes observed across different ethnic groups may be due to a genetic gradient resulting from historical human migrations and genetic drift.
This study explored the structure and function of lipocalin prostaglandin D synthase, revealing its dual role in substrate catalysis and as a lipophilic ligand carrier, potentially informing future drug delivery design.
December 2015 in “Basrah Journal of veterinary Research” In this study, researchers found that most buffaloes in Basrah, Iraq, suffered mineral deficiencies, especially in zinc, cobalt, copper, and sulfur, with outdoor grazing buffaloes displaying more severe deficiencies than those kept indoors.
This research focused on formulating finasteride, dutasteride, and minoxidil with cyclodextrins to enhance their solubility and skin penetration for topical use, potentially reducing scalp irritation from current alcohol-based preparations.
51 citations
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November 2010 in “Dermatologic Surgery” This study measured the lengths and depths of different portions of occipital scalp hair follicles and suggested cutting below 1 mm for hair regeneration procedures to avoid damaging the bulge zone.
July 2026 in “International Journal of Drug Delivery Technology” This study evaluated a Piper betle leaf emulgel for topical use and found it to have good stability, non-irritant properties, and significant hair growth activity in albino mice, suggesting its potential for dermatological and hair growth applications.
This study found that gels containing glycyrrhizic acid and aqueous Glycyrrhiza glabra extract significantly reduced underarm hair growth in terms of area, thickness, length, and number compared to their gel bases.
39 citations
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November 2015 in “Nanomedicine” This study found that the developed Finasteride-loaded SMEDDS improved the relative bioavailability of the drug compared to a commercial tablet, offering a promising oral delivery system for glucosteroid analogs.
April 2012 in “Lab Animal” Early exposure to germs may protect against autoimmune diseases, lack of sex increases alcohol preference in fruit flies, a potential baldness treatment could involve blocking a specific receptor, skin memory cells help prevent re-infection, high-fat diets can affect brain cells related to weight, and the link between social status, stress, and heart disease in primates is unclear.
35 citations
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January 1993 in “International Journal of Dermatology” In this study, most hair disorders among HIV-1 positive patients were associated with low helper T cell counts, with papulosquamous conditions like seborrheic dermatitis and psoriasis being the most common.
6 citations
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May 2011 in “Pharmacognosy Journal” This review discusses the causes of alopecia, including androgenetic alopecia, and potential active ingredients for hair regrowth, but it does not report new clinical results.
208 citations
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January 2013 in “Lab on a Chip” The researchers described a chip-based bioreactor platform for dynamic perfusion, which may enhance in vitro skin models by introducing mechanical shear stress and extending culture periods.
26 citations
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February 2012 in “Journal of Investigative Dermatology” This study found that dermal papilla cells from human hair follicles can be reprogrammed into induced pluripotent stem cells, but their efficiency is similar to that of fibroblasts, unlike in mice.
101 citations
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December 2010 in “The journal of investigative dermatology/Journal of investigative dermatology” This study reports the successful differentiation of mouse induced pluripotent stem cells into keratinocytes that can regenerate skin and its structures in an in vivo environment.
76 citations
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August 2018 in “International Journal of Cosmetic Science” This review discusses the use of Dermal Papilla cells as in vitro models for studying hair growth modulators, emphasizing their role in aiding the development of new hair treatments, but reports no new clinical results.
63 citations
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September 2009 in “Regenerative Medicine” This study developed a method for expanding human dermal papilla cells in vitro while maintaining their ability to induce hair growth, advancing the potential for follicular cell implantation as a treatment for hair loss.
34 citations
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December 2000 in “The journal of investigative dermatology/Journal of investigative dermatology” This study observed that rat vibrissa hair follicles cultured in vitro showed morphological changes suggesting cyclical activity but remained blocked in the pro-anagen stage.
7 citations
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November 2020 in “Experimental Dermatology” This article reviews skin regeneration and fibrosis, identifying key cellular and molecular players, and emphasizing the potential to manipulate the postwound environment to promote regeneration over fibrosis.
January 2024 in “OPAL (Open@LaTrobe) (La Trobe University)” In this study, researchers explored various aspects of the TRPV3 ion channel, including its novel mechanosensitivity to shear stress, and identified novel agonists while investigating how repeated stimulation affects TRPV3 activity, but found no evidence of GPCRs sensitizing the channel.
66 citations
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May 2012 in “Scientific Reports” This study demonstrated that bioengineered hair follicles reconstituted from embryonic skin cells and transplanted into hosts can restore physiological hair functions, suggesting potential applications for treating alopecia.
30 citations
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April 2013 in “Journal of Investigative Dermatology” This study found that ionizing radiation primarily affects keratinocyte stem cells in the hair follicle, suggesting they play a central role in radiation-induced hair graying, rather than melanocyte stem cells.
8 citations
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October 2020 in “Pharmaceutics” This study explored using a chitosan oligomer coating for topical delivery of dutasteride-loaded nanostructured lipid carriers, aiming to reduce systemic exposure and cytotoxicity.
7 citations
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December 2017 in “Open Access Macedonian Journal of Medical Sciences” This abstract outlines the historical development and medical validation of artificial hair implants, particularly the approval and improvement of the Biofibre® implant technique in Europe and Australia, and highlights its advantages as the latest advancement in hair restoration treatments.
December 2023 in “Scientific reports” This study assessed three lactic acid bacteria-fermented proteins and found that F-WPI and F-SPI could normalize osteoclastogenesis markers in vitro, while F-SPI enhanced osteoblastogenesis markers, suggesting potential as dietary supplements for osteoporosis prevention, though further research into mechanisms is needed.
November 2023 in “International journal of Ayurveda and pharma research” This study prepared and evaluated a polyherbal hair oil using plant-based ingredients, finding that it met standard parameters and effectively addressed hair problems such as growth and dandruff, with FDA approval for clinical use.
July 2023 in “Journal of medical and health studies” This case study reported on a 3-year-old child with vitamin D-dependent rickets type II treated in the Gaza Strip, whose condition deteriorated despite vitamin D and calcium treatments, leading to recurrent chest infections, respiratory failure, and eventual death.