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The document concludes that adenosine receptor agonists have potential for treating various conditions, but only a few are approved due to challenges like side effects and the need for selective activation.

Small molecule drugs show promise for advancing regenerative medicine but still face development challenges.

Vitamin D and estrogen may help protect heart and kidney health, and maintaining sufficient vitamin D levels could be especially beneficial for African Americans, postmenopausal women, and people with chronic kidney disease.

SLVs help maintain muscle stretch sensitivity and could aid in treating hypertension and muscle spasticity.

Vitamin D might help regulate insulin in the body, but taking Vitamin D supplements doesn't clearly prevent or improve type 2 diabetes. More research is needed.

Selective breeding caused the unique curly hair in Mangalitza pigs.

Some common medications can harm male fertility, but many effects can be reversed.

The document concludes that skin biopsies, genetic and environmental factors, and specific treatments are important in managing cutaneous lupus erythematosus.

Drug repurposing shows promise for treating many medical conditions.

The TRPV3 ion channel is important for skin and hair health and could be a target for treating skin conditions.

Calcium affects where root hairs grow, but other unknown factors determine their growth direction.

CRAC channels are crucial for the development and function of specialized immune cells, preventing severe inflammation and autoimmune diseases.

The research found two types of calcium in human hair, one that varies among individuals and another that is consistent across people.

Potassium channel openers could help treat cardiovascular diseases and asthma but require better targeting to specific tissues for effective use.

Ice-skating athletes often have skin problems due to cold, infections, and inflammation, needing careful treatment and prevention.

Hair thinning causes stem cell loss through a process involving Piezo1, calcium, and TNF-α.

Pannexin 3 is important for bone formation and the development of bone cells.

A specific signal from hair cells controls the tightening of the surrounding muscle, which is necessary for hair shedding.

Cyanidin 3-O-arabinoside may help treat a common form of hair loss by protecting cells against aging and improving cell function.

The CAP1 gene helps control ammonium levels and is necessary for the proper growth of root hairs in Arabidopsis.

Women experience more side effects and have worse blood pressure control from hypertension treatments than men, despite using different medications.

Parathyroid hormone-related protein helps control hair growth phases in mice.

The enzyme 5α-reductase type 1 is important for blood vessel development and fertility in the uterus.

The STIM1 R304W mutation in mice leads to bone changes and teeth hair growth.

TRP channels in the skin are important for sensation and health, and targeting them could help treat skin disorders.

A mix of tocopherol acetate and L-menthol helps grow hair better than using them separately or using minoxidil.

Vitamin D and calcium are important for quick and effective skin wound healing.

Potassium channel openers show promise for treating heart disease and other conditions, but more research is needed to fully understand their effects and safety.

The enzyme 5α-reductase is important for proper blood vessel development during the fertility-related transformation of the uterus lining.

Higher hair calcium to magnesium ratios and lower chromium levels in hair may indicate insulin resistance in Korean men.