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The document concludes that certain mutations may contribute to the inflammation in hidradenitis suppurativa and suggests that targeting TNFα could be a treatment strategy.

Blocking Wnt/β-catenin signaling with EGF receptor is necessary for proper hair growth.

Steroid Sulfatase inhibitors show promise in treating hormone-dependent disorders like cancers, hair loss, and acne, with 667COUMATE being a potential candidate for breast cancer treatment trials.

The hair keratin gene KRT81 is found in both normal and breast cancer cells and helps them invade surrounding tissues.

Diffuse alopecia areata involves more inflammation and higher allergy-related antibodies than patchy types.

Mutations in the HEPHL1 gene cause abnormal hair and cognitive issues.

A drug improved schizophrenia-like symptoms in stressed rats by changing brain steroid levels.

Betacoronaviruses, like COVID-19, may cause hormone system dysfunction and affect disease susceptibility and severity.

Hair loss in Rhesus macaques may be caused by a skin allergy-related condition.

Finasteride may negatively affect male fertility.

Treatment can improve survival and symptoms in dogs with Cushing's disease, but outcomes are unpredictable.

African American men with prostate cancer have more androgen receptor mutations, which may lead to more aggressive cancer compared to Caucasian American men.

The oral glucose tolerance test is effective in detecting abnormal glucose tolerance in Indian women with PCOS.

More adolescent girls in urban areas of India have Polycystic Ovary Syndrome compared to those in rural areas.

Family members of North Indian women with PCOS have a high rate of metabolic syndrome.

Early stage bald spots are linked to skin inflammation and damage to the upper part of the hair follicle.

DHT affects hair follicle cells by changing microRNA levels, leading to less cell growth and more cell death.

Scientists have developed a new method to detect steroid abuse in athletes using cell-based tests, which could be the future of anti-doping methods.

Low-level laser therapy significantly increases hair density in adults with hair loss, with low-frequency treatment being more effective.

Greek women with PCOS have a higher risk of metabolic syndrome and are more likely to be overweight compared to healthy controls.

The document reports the first Brazilian case of a girl with Becker nevus syndrome, characterized by skin changes, breast underdevelopment, and scoliosis.

Green-synthesized nanoparticles can effectively target cancer cells, reducing side effects and improving treatment.

Progesterone byproduct 5αP stimulates mammary tumor growth, but finasteride can suppress it.

Spermidine helps protect against aging by preserving telomere length.

Spironolactone may help reduce hair loss in androgenic alopecia.

Genetic factors alone might not cause pemphigus vulgaris; other factors like birth complications and puberty may trigger it.

Male hormones indirectly affect skin cell development by increasing growth factor levels from skin fibroblasts.

Moderately high prolactin levels do not cause hair loss in women.

The document concludes that Functional Hypothalamic Amenorrhea should be carefully diagnosed and managed to prevent health complications, using lifestyle changes and specific medications.

UVB radiation changes the levels of certain microRNAs in skin cells, which may affect cell survival and hair growth.