3 citations
,
December 2021 in “Recent patents on anti-cancer drug discovery” This review examines the role of SET7/9 in non-histone methylation and its implications in various diseases, including cancer, but presents no new clinical results.
70 citations
,
June 2010 in “Clinics in Dermatology” This review discusses how changes in hair and skin may indicate underlying vitamin deficiencies and emphasizes the need to identify populations at risk for these deficiencies; it reports no new results.
7 citations
,
January 2010 in “Animal” This review discusses studies on hair growth and protein synthesis in hair follicles, highlighting the differing responses of mohair and cashmere goat follicles to signaling molecules, biotin, and amino acids, but contains no new results.
1 citations
,
May 2009 in “Annales de Dermatologie et de Vénéréologie” This article reviews environmental factors contributing to androgenic alopecia and emphasizes the importance of giving patients advice to manage hair loss; it reports no new clinical findings.
35 citations
,
January 2006 in “Journal of Dermatological Treatment” This review found little evidence supporting zinc as a first-line treatment for dermatological conditions, except in cases of systemic zinc deficiency, and suggests further research is needed.
October 2023 in “Animal production science” This study investigated how vitamin A deficiency, certain diseases, and pregnancy affect cattle coat hair structure, finding notable keratin fibril interference under vitamin A deficiency and structural modifications in chronic renal failure, while pregnant cows exhibited superior hair tensile strength compared to non-pregnant ones.
68 citations
,
September 2018 in “Trends in Cell Biology” This review discusses the senescence–stemness connection in cellular biology and reports no new findings, highlighting implications for both tissue repair and aggressive cancer behavior.
19 citations
,
January 2015 in “Current problems in dermatology” This review discusses environmental factors like UV radiation and smoking that affect hair health and highlights the potential role of nutrition, but it reports no new results.
18 citations
,
April 2013 in “Inflammatory Bowel Diseases” This review discusses the various potential causes of hair loss in patients with inflammatory bowel disease, including telogen effluvium from disease flares, but provides no prevalence data; the authors outline a practical assessment and management approach.
11 citations
,
January 2011 in “Turkish Journal of Medical Sciences” This study found that iron deficiency anemia is a key factor in the development of telogen effluvium, and higher 25-hydroxyvitamin D3 levels in TE patients may be linked to increased UV exposure.
June 2023 in “International journal of research in ayurveda and pharmacy” This study explores how Dhatryadi rasayana, a polyherbal formulation with antioxidant properties, may help prevent and treat premature hair greying by addressing factors such as oxidative stress, nutritional deficiencies, and hormone imbalances, potentially through rasayana therapy.
January 2017 in “International journal of clinical & experimental dermatology” This review discusses how nutritional and lifestyle modifications, including antioxidant use, may enhance hair growth and prevent hair loss without the need for Finasteride, but provides no new clinical findings.
117 citations
,
November 2006 in “Experimental Dermatology” This review explores the biology of wool follicles and suggests their potential use as research models in modern biology, but it reports no new findings.
29 citations
,
August 2017 in “Skin appendage disorders” This study found that IGF-1 likely plays a crucial role in regulating hair growth and alopecia, with balding scalp follicles secreting less IGF-1 than nonbalding counterparts.
4 citations
,
January 2015 in “Journal of microbial & biochemical technology” In this study, the researchers observed that biotin administration in biotin-deficient children with alopecia eliminated certain membrane proteins from their blood, suggesting that biotin might regulate these proteins' expression.
2 citations
,
October 2020 in “Journal of Pharmacology and Experimental Therapeutics” This study found that in a mouse model of bronchopulmonary dysplasia, minoxidil administered at 50 mg/kg/day did not impact lung development or inhibit lysyl hydroxylation.
May 1991 in “Current problems in dermatology” This article reviews the relationship between the skin and the immune system and discusses how skin manifestations can indicate immunodeficiencies but reports no new research findings.
4 citations
,
August 2025 in “Scientific Reports” This study found that hair analysis is an effective non-invasive method for assessing metabolic fluctuations, showing stable advanced glycation end products levels that correlate with age and differ significantly between diabetic and non-diabetic rats.
24 citations
,
January 2020 in “International Journal of Molecular Sciences” This review discusses the potential benefits of flavonoid-containing botanicals, such as Panax ginseng, in reducing hair loss and promoting hair growth, but reports no new experimental results.
February 2025 in “Animals” This study found that senior dogs fed amino acid-complexed and lysine-glutamic acid-complexed trace minerals had longer, faster-growing hair and increased activity compared to those fed inorganic trace minerals.
13 citations
,
February 2020 in “CHEST Journal” This case report observed that pulmonary arterial hypertension in a man with severe vitamin C deficiency resolved after vitamin C supplementation, suggesting a potential role of vitamin C in managing this condition.
25 citations
,
January 2017 in “International Journal of Trichology” This study found that nutritional deficiencies, particularly in amino acids and certain micronutrients, are common in individuals with hair loss across all types of alopecia.
166 citations
,
November 2008 in “Expert Review of Endocrinology & Metabolism” This review discusses biotin and biotinidase deficiencies, their symptoms, and methods of medical management, without presenting new clinical findings.
3 citations
,
January 2021 in “Molecular genetics & genomic medicine” In this study, novel mutations in the BTD gene were identified in a patient with profound biotinidase deficiency, highlighting the importance of biotinidase activity measurement and mutation analysis for early diagnosis.
6 citations
,
July 2021 in “Frontiers in Genetics” This study identified a new heterozygous missense variant in CST6 associated with autosomal dominant keratosis follicularis spinulosa decalvans in an Austrian family, affecting epidermal differentiation and hair formation.
4 citations
,
July 2022 in “The Journal of Clinical Endocrinology & Metabolism” This study identified a novel homozygous mutation in the 5'-UTR of the POMC gene, suggesting a new molecular mechanism for the syndrome of adrenal insufficiency, obesity, and red hair.
This study in mice found that maternal iron deficiency led to hair loss and growth abnormalities in offspring due to increased oxidative stress and disrupted signaling pathways, but postnatal iron supplementation was able to reverse these effects.
59 citations
,
July 1972 in “Biochemistry” This study investigated the formation of a specific chemical crosslink in hair proteins and explored the role of transamidase enzymes in hair follicles.
February 2019 in “International Journal of Dermatology and Clinical Research” In this study, Nε-(carboxymethyl) lysine was found to weaken hair follicle morphogenesis and inhibit essential cell activities in a model simulating accumulated glycation.
August 2025 in “Frontiers in Pharmacology” In this study, PA-011, a traditional Chinese medicine extract, was shown to improve hair growth in alopecia areata model mice by reducing skin inflammation and altering skin microbiota, indicating its potential therapeutic role for this condition.