May 2022 in “Maǧallaẗ Buḥūṯ Al-Tarbiyyaẗ Al-Nawʿiyyaẗ (Print)” In this study, a high inositol diet, with or without supplements, significantly improved androgen levels, insulin sensitivity, and certain metabolic indicators in women with PCOS over three months.
84 citations
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August 2013 in “Journal of Cellular Biochemistry” This study found that stem cells from the human umbilical cord's Wharton's jelly may significantly enhance healing in excisional and diabetic wounds compared to controls.
75 citations
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September 2016 in “EMBO journal” This study found that PRC2 plays a crucial role in maintaining intestinal homeostasis by supporting progenitor cell proliferation and limiting secretory lineage differentiation.
61 citations
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July 2011 in “PLOS ONE” This study provides the first direct evidence that spermidine can stimulate hair growth and modulate human epithelial stem cell biology in cultured human hair follicles.
32 citations
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May 2018 in “The Plant Cell” This article discusses the crucial role of root hairs in water and nutrient uptake from soil and reports no new findings.
4 citations
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June 2023 in “Frontiers in Aging” This scoping review evaluates the connection between hypoxia and declining sex hormonal signaling in middle-aged individuals, proposing a "middle-aging hypovascularity hypoxia hypothesis" as a potential mechanism influencing age-related diseases, with implications for developing strategies to maintain healthspan.
1 citations
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January 2021 in “Indian Dermatology Online Journal” This expert group provided recommendations for preparing and using platelet-rich plasma in treating androgenetic alopecia, suggesting a manual double-spin method and specific dosing, although further studies on injectable platelet-rich fibrin are needed.
March 2026 in “Journal of Investigative Dermatology” Folliculin slows hair growth, and blocking it might help treat hair loss.
This review highlights the increasing global incidence and broad socio-economic impact of celiac disease, emphasizing the need for improved recognition and management to address its multidimensional implications, including comorbidities and dietary challenges.
This study found that targeting S1PR1 signaling in mouse aortic endothelial cells helps suppress inflammation-related gene expression while revealing diverse and spatially distinct endothelial cell subtypes.
11 citations
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March 2023 in “Marine Drugs” In this study, researchers isolated five new compounds from Monascus purpureus wmd2424 and found that four exhibited mild antifungal activity against several fungi.
October 2025 in “Nephrology Dialysis Transplantation” In this case report, a young woman experienced acute kidney injury linked to the use of a hair straightening product containing glyoxylic acid, suggesting dermal absorption may lead to calcium oxalate nephropathy; this highlights the need for regulatory review and public health intervention.
June 2026 in “Restorative Dermatology and Venereology and Cosmetology” This study found that a combination of the Tri-energy factor 5.5% booster and photodynamic therapy significantly improved hair density and reduced single follicular units in patients with androgenetic alopecia, compared to minoxidil or booster alone, supporting the inclusion of photodynamic therapy in comprehensive treatment.
January 2022 in “Sustainable development goals series” The document concludes that significant investment in agricultural innovation is necessary to achieve global food security and nutrition.
18 citations
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January 2015 in “Data series” This report describes a study of estuarine bed-sediment quality in New Jersey and New York post-Hurricane Sandy, focusing on contamination extent and potential long-term impacts, with no new findings included.
21 citations
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March 2018 in “American Journal Of Pathology” In this study, it was observed that NIPAL4 mutations linked to autosomal recessive congenital ichthyosis lead to abnormal skin barrier function due to cytotoxic effects disrupting lipid structure and organization, which topical treatments only partially ameliorated.
11 citations
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January 2000 in “The Journal of Steroid Biochemistry and Molecular Biology” This study found that LY320236 is a competitive inhibitor of type I and a non-competitive inhibitor of type II steroid 5alpha-reductase, indicating its potential as a dual inhibitor with differing modes of activity.
66 citations
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October 2002 in “Human molecular genetics online/Human molecular genetics” This study found that a nonsense mutation in the Cst6 gene of mice leads to severe skin and hair abnormalities, suggesting that cystatin M/E is crucial for epidermal function and viability.
July 2022 in “Al-Mağallaẗ al-ʻirāqiyyaẗ li-l-ṣaydalaẗ” This study found that among women with hirsutism, the most common type of non-scarring alopecia observed was androgenetic alopecia with telogen effluvium.
June 2023 in “Al-Mağallaẗ al-ʻirāqiyyaẗ li-l-ṣaydalaẗ” In this study, researchers found that high doses of rosemary extract given to lactating mother rats adversely affected their offspring, causing weight issues and damage to liver, kidney, and testis tissues, suggesting potential teratogenic risks if used during human pregnancy and lactation.
26 citations
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April 2019 in “Genes” In this study, researchers identified novel long non-coding RNAs related to cashmere fineness in goats, highlighting a potential regulatory network involving lncRNA XLOC_008679 and its target gene KRT35.
April 2017 in “The journal of investigative dermatology/Journal of investigative dermatology” This study investigates whether lymphocytes from mice with secondary alopecia areata can effectively induce the disease in a C3H/HeH mouse model, similar to lymphocytes from mice with spontaneous disease.
30 citations
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December 2001 in “Experimental dermatology” This study found that gonadal steroid hormones influence alopecia areata in C3H/HeJ mice, with estradiol promoting progression and dihydrotestosterone conferring resistance to disease onset.
451 citations
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March 2005 in “Endocrine Reviews” This paper discusses the role of steroid sulfatase in hormone-dependent tumors and highlights the development of potent inhibitors, noting the commencement of a phase I trial for one inhibitor in postmenopausal breast cancer patients.
369 citations
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June 2013 in “Biochimie” This review discusses the potential benefits of myo-inositol supplementation for insulin resistance-related disorders and diabetic complications, but reports no new clinical results.
109 citations
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November 2004 in “Lupus” This article reviews the current ACR classification criteria for systemic lupus erythematosus, highlighting their dermatologic limitations, and proposes guidelines for a study to update these criteria.
109 citations
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April 2000 in “European Urology” In this study, significantly fewer men treated with finasteride for moderate to severe BPH symptoms experienced acute urinary retention or required subsequent BPH-related surgery compared to placebo-treated patients.
82 citations
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February 1989 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism” This study found that in men with benign prostatic hyperplasia, a 3-month treatment with a long-acting GnRH agonist significantly reduced intraprostatic DHT and 3α-diol levels by about 90% and testosterone by about 75%.
70 citations
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August 1995 in “Fertility and Sterility” In this study, women with idiopathic hirsutism who took finasteride for 9 months experienced a significant reduction in hirsutism scores compared to those receiving a placebo, with minimal side effects.
60 citations
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November 2013 in “Development” This study found that the creation of hair follicle lumens in mice is driven by the outward migration of keratin 79-positive cells, suggesting a novel mechanism for generating hollow cores in hair follicles.