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In this study, intrathecal progesterone administration initially worsened mechanical allodynia in mice after nerve injury, but later reduced pain when applied during the maintenance phase, highlighting distinct roles for cytochrome P450c17 and 5α-reductase in neuropathic pain modulation.

This study found that children with celiac disease who adhered to a gluten-free diet experienced significant improvements in height, weight, and symptoms like diarrhea and abdominal pain, although cases of abdominal distention increased.

This study reports that extracts from pomegranate leaves contain bioactive compounds with antioxidant, antimicrobial, and skin-beneficial properties, suggesting their potential use in nutraceutical and cosmeceutical applications.

This integrative literature review investigated clinical trials on using medicinal plants, herbal products, and dietary supplements for treating alopecia, noting a need for further studies due to limited chemical-pharmaceutical analyses of the plant species involved, which include Allium sativum and Rosmarinus officinalis.

This study found that the combination of TTNPB and CHIR99021 enhanced the derivation of highly advanced neural stem cells from human pluripotent stem cells, with improved chromatin accessibility and neuroectodermal gene expression, and these cells successfully engrafted in rat hippocampi to ameliorate depression-like symptoms.

This review discusses the diverse industrial applications of hemp beyond traditional fiber uses, highlighting its phytochemical components with antioxidant and antimicrobial properties that are explored in agrochemicals, cosmetics, and food sectors.

This research reported that KDML105 bran extract demonstrated antioxidant activities, reduced nitric oxide production, and influenced gene expression related to the hair cycle in cultured dermal papilla cells, suggesting potential as an anti-hair loss agent by supporting the anagen phase and angiogenesis.

In this exploratory randomized controlled trial, participants using a combination of Centella asiatica-derived extracellular vesicles with recombinant growth factors showed significant improvements in hair thickness, density, length, and reduced hair loss and scalp sebum content after 56 days, compared to placebo.

This study identified various secondary metabolites such as terpenes, phenolic acids, and flavonoids in plants mentioned by Ibnu Sina for hair cosmetic applications.

This study reported that Cyperus rotundus L., a plant used in traditional medicine, effectively reduces hair growth with minimal side effects, showing efficacy comparable to Alexandrite laser treatments in certain cases, particularly for white hair, positioning it as a potential natural alternative to chemical depilatories.

This review discusses the potential of metabolic engineering to enable sustainable industrial-scale production of L-aspartate and its derivatives, detailing current microbial production progress, limiting factors, and future prospects with emerging technologies in synthetic biology.

In this study, topical application of tonic preparations containing 5% ethanol extract of Phyllanthus niruri to shaved mice showed potential as a hair growth enhancer, as indicated by observations of increased hair length and weight over a 21-day period.

This study's literature synthesis suggests that silymarin, derived from milk thistle, may offer protective benefits for the skin, including defense against UV damage and support for wound healing, though further clinical studies are needed.

In this study, a hydro-alcoholic extract of Urtica dioica demonstrated in vitro antioxidant activity, potentially linked to its ferulic acid content.

This study found that multi-walled carbon nanotubes promoted root hair growth in certain plants, with results indicating they modulate nitric oxide and ethylene pathways crucial to this development.

In this animal study, rosehip seed oil applied to the skin of mice promoted hair regrowth by accelerating hair follicles' transition from resting to growth phases and increased hair follicle density, bulb size, and skin thickness, suggesting potential as a treatment for hair loss.

This study reported that rice bran oil from the Thai rice variety BB4CMU showed potential in promoting melanin production and inhibiting steroid 5α-reductase, suggesting a natural option for hair revitalization.

This study demonstrated that genetically engineered stem cells from human hair follicles can reverse hyperglycemia and reduce mortality in mice with type 1 diabetes by overexpressing the human insulin gene.

Melatonin helps broccoli roots produce anti-cancer compounds by controlling nitric oxide and hydrogen peroxide levels.

This study suggests that CSLD1 is key to nitrogen-dependent root hair elongation and regulation of AMT1;2 expression in rice roots.

This study found that ethanolic extracts of Buebang 3 CMU may promote hair growth and prevent hair loss more effectively than minoxidil by enhancing bioactive compounds and activating key signaling pathways.

This study found that a combination of four transcription factors can transform mouse fibroblasts into cells resembling inner ear hair cells, potentially aiding research into hearing loss treatments.

This narrative review discusses advancements in the understanding and treatment of dermatitis herpetiformis as a manifestation of celiac disease and reports no new research results.

This study found that co-transplanting mouse epidermis and dermis cells induced new hair follicle formation, while isolated or cultured dermis cells contributed to follicle-related structures differently.

This study found that S1PR1 signaling in mouse aortic endothelial cells varied by location and subtype, influencing inflammatory and lymphangiogenic gene expression through distinct molecular pathways.

This study suggests that mutation-targeted siRNA therapy could potentially treat keratitis-ichthyosis-deafness syndrome by selectively reducing harmful GJB2 mutant gene expression in patient-derived keratinocytes.

This review summarizes recent findings on how the dysregulated PI3K/Akt/mTOR pathway contributes to immune-mediated inflammatory skin disorders and discusses the potential of natural products, synthetic compounds, and biologic agents in their treatment. However, it emphasizes the need for further research to develop effective therapies.

In a murine model of androgenetic alopecia, this study found that the newly designed IGF-1 biomimetic peptide Ac-GFFY-IGF led to faster and superior hair regrowth compared to minoxidil, suggesting potential for improved human therapies.

This study demonstrated that ND-GFP stem cells from the hair-follicle bulge area can differentiate into various cell types, including neurons, suggesting their potential as a source for therapeutic applications.