October 2025 in “Frontiers in Pharmacology” This review explores the immunopharmacological potential of A. lappa for inflammatory musculoskeletal disorders (IMSDs) but reports no new clinical results, emphasizing the need for standardized research methodologies.
May 2025 in “Journal of Traditional Chinese Medical Sciences” In this study, S. chamaejasme extract applied topically to mice enhanced hair growth dose-dependently by increasing hair follicle size and dermal thickness, while upregulating mRNA expression related to hair growth, suggesting its potential as a hair growth treatment.
April 2025 in “Mutiara Jurnal Penelitian dan Karya Ilmiah” In this study of Beauty and Aesthetics students, researchers found that using a hair tonic made from Green Spinach Leaves significantly reduced hair loss when applied weekly, compared to a control, but no significant difference was observed when increasing application to twice weekly.
August 2023 in “Vittalle” This integrative literature review investigated clinical trials on using medicinal plants, herbal products, and dietary supplements for treating alopecia, noting a need for further studies due to limited chemical-pharmaceutical analyses of the plant species involved, which include Allium sativum and Rosmarinus officinalis.
May 2023 in “Scientific Reports” This study found that Lepidium sativum seed extract showed potential in treating alopecia in rats by reducing 5(alpha)-dihydrotestosterone levels and improving hair length compared to minoxidil.
This review evaluates the literature on the ethnopharmacology, phytochemistry, and therapeutic potential of Darmana Turki (Artemisia maritima L.) and reports no new clinical findings.
April 2016 in “Pharmaciana” This study found that a combination of liquorice and aloe vera extracts, particularly combination 1, resulted in the most optimal hair growth in rabbits over a 28-day period.
December 2025 in “Sustainable Chemistry One World” In this study, researchers found that mangosteen pericarp extract, combined with FeSO₄ as a mordant, effectively produced a stable reddish hair dye on bleached hair, with good color persistence and enhanced tensile strength, indicating its potential as an eco-friendly and safer alternative to synthetic dyes.
113 citations
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June 2015 in “Stem Cell Research & Therapy” This study found that activation or inhibition of Wnt/β-catenin and Notch signaling pathways in rats can alter wound healing, possibly by affecting epidermal stem cell activity and keratinocyte behavior.
44 citations
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May 2014 in “The American Surgeon” In this study, hair loss after laparoscopic sleeve gastrectomy was associated with zinc and iron levels, even within normal ranges, and a combined variable of zinc and iron predicted susceptibility to hair loss.
32 citations
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January 2012 in “Chinese Medicine” In this study, a hydro-alcoholic extract of Urtica dioica demonstrated in vitro antioxidant activity, potentially linked to its ferulic acid content.
6 citations
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October 2023 in “Pharmaceuticals” This study found that the extract of Eclipta prostrata L. demonstrated high antioxidant and anti-acetylcholinesterase activities, moderate inhibition of enzymes linked to diabetes, and favorable ADMET properties, suggesting potential cognitive and diabetes management benefits.
2 citations
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March 2023 in “Experimental neurology” In this study, pregnenolone was found to dose-dependently reduce L-DOPA-induced dyskinesias in a rat model of Parkinson's disease, suggesting its potential as a therapeutic target for these dyskinesias.
1 citations
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October 2023 in “International Journal of Women s Health” In this study, scalp hydration and pH levels were not significantly different between hijab-wearing and non-hijab-wearing women, suggesting that hijab-wearing does not impair scalp health if there's no history of underlying scalp or skin disorders and the hijab is not worn damp.
1 citations
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July 2022 in “Evidence-based Complementary and Alternative Medicine” This study found that high-flux hemodialysis combined with L-carnitine improved heart function, reduced inflammation, and decreased venous fistula complications in maintenance hemodialysis patients.
February 2026 in “Materials” This study evaluated Humulus lupulus (hops) extract in cosmetic formulations and found it to maintain antioxidant and anti-irritant properties, reducing erythema by 10% after three weeks of use, supporting its potential for skin health improvement in plant-based cosmetics.
January 2026 in “Lithuanian University of Health Sciences” This study reported that gels containing methyl cellulose exhibited the highest consistency factor and optimal homogeneity compared to those made with hydroxypropyl cellulose or its combination with pullulan, indicating the significant impact of gelling agents on gel properties.
August 2025 in “Current Issues in Molecular Biology” This study demonstrated that Periplaneta americana extract significantly promoted hair regeneration in depilated mice by enhancing superoxide dismutase activity, upregulating vascular endothelial growth factor, modulating the FOXO/PI3K/AKT pathway, and restoring skin microbiome balance, suggesting its potential as a novel therapeutic candidate for alopecia.
May 2025 in “International Journal of Molecular Sciences” In a mouse study, Fr2 from Platycladus orientalis L. significantly enhanced hair growth, suggesting its potential as a natural therapeutic agent for hair regeneration.
March 2024 in “Journal of Evidence-Based Integrative Medicine” This study found that a hair tonic containing 1% teak leaf extract significantly increased hair growth and user satisfaction in men with androgenic alopecia after 24 weeks, without causing adverse effects, and was comparable to the standard treatment, minoxidil.
April 2022 in “Molecules” This study identified two potent 5α-reductase inhibitors from Tectona grandis leaves, and suggests that ethanol is a preferable solvent for extracting these compounds, which are potential ingredients for hair loss treatments.
353 citations
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November 2014 in “Molecular immunology” This review discusses the immune functions of porcine skin and proposes a classification of dendritic cell subsets based on similarities to human skin, but it reports no new clinical results.
6 citations
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December 2019 in “BMC Complementary and Alternative Medicine” This study found that the alcohol extract of Vernonia anthelmintica may counteract stress-induced hair follicle growth inhibition in mice, potentially offering a new approach for treating stress-related hair loss.
1 citations
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September 2025 in “Cosmetics” This study's literature synthesis suggests that silymarin, derived from milk thistle, may offer protective benefits for the skin, including defense against UV damage and support for wound healing, though further clinical studies are needed.
May 2023 in “Endocrine, metabolic & immune disorders” This review describes the diverse pharmacological and phytochemical properties of Hibiscus rosa-sinensis, noting its wide range of traditional medicinal uses and safety at higher extract doses.
February 2022 in “Research Journal of Biotechnology” This review discusses the taxonomy, traditional uses, and pharmacological activities of the medicinal plant Eclipta alba but reports no new clinical findings.
December 2021 in “Prosiding Seminar Nasional Kesehatan” In this study, the hair tonic made from the ethanol extract of bandotan leaves, applied on local male rabbits for 21 days, demonstrated significant hair growth activity, especially at a 20% concentration, showing the highest hair length and weight improvements.
This study characterized Eclipta alba for use in a capillary product for alopecia, confirming its suitable physico-chemical properties and pharmacological constituents, including wedelolactone for hair growth.
27 citations
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January 2016 in “Cellular Physiology and Biochemistry” This study found that the extract of Bidens pilosa L. improved dry eye symptoms associated with androgen deficiency in rats by enhancing tear production, stabilizing the tear film, and reducing lacrimal gland inflammation.
15 citations
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November 2020 in “International Journal of Molecular Sciences” This study found that multi-walled carbon nanotubes promoted root hair growth in certain plants, with results indicating they modulate nitric oxide and ethylene pathways crucial to this development.