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Twist1 helps maintain important features of cells crucial for hair growth by working with Tcf4 and β-catenin.

A mutation in the Adam10 gene causes freckle-like spots on Hairless mice.

The research identified genes that explain why some sheep have curly wool and others have straight wool.

Rare changes in the KRT82 gene are linked to a higher risk of Alopecia Areata.

Natural gene therapy shows promise for treating skin disorders like epidermolysis bullosa.

The document concludes that the human keratin gene cluster is complex, with a need for updated naming to reflect over 50 functional genes important for hair and skin biology.

Adult stem cells with Tp63 can form hair and skin cells when placed in new skin, showing they have hidden abilities for skin repair.

Different problems with hair stem cell renewal can lead to hair loss.

Mutations in Plcd1 and Plcd3 together cause severe hair loss in mice.

A specific group of slow-growing stem cells marked by Thy1 is crucial for skin maintenance and healing in mice.

Hair loss can indicate or worsen with systemic diseases, and treating the underlying condition is important.

Key genes can rewire networks, changing skin appendage types.

Keratin is crucial for keeping skin cells healthy and its changes can lead to diseases and affect cell behavior.

SOX9 helps determine stem cell roles by interacting with DNA and proteins that control gene activity.

Keratin genes change gradually during skin cell development and should be used carefully as biomarkers.

STAT3 signaling is important for healthy skin and hair follicles, and its disruption can lead to skin conditions like atopic dermatitis.

Researchers identified genes and proteins that may influence wool thickness in sheep.

Using special RNA to target a mutant gene fixed hair problems in mice.

The document concludes that more research is needed to understand airway repair and to improve tissue engineering for lung treatments.

Bald thigh syndrome in sighthounds is caused by structural defects in hair shafts due to downregulated genes and proteins.

Activating TLR3 may help produce retinoic acid, important for tissue regeneration.

Ingenol mebutate gel changes gene expression related to skin development and immune response in actinic keratosis.

Genetically modified sheep with more β-catenin grew more wool without changing the wool's length or thickness.

Compounds from certain trees used by First Nations people show potential for treating skin conditions and promoting hair growth, but more research is needed to confirm their safety and effectiveness.

The research reveals how early embryonic mouse skin develops from simple to complex structures, identifying various cell types and their roles in this process.

PNKP is essential for keeping adult mouse progenitor cells healthy and growing normally.

Genes related to keratin, skin cell differentiation, and immune functions are key in hedgehog skin and spine development.

Two patients with the same genetic mutation had both blistering skin and easily pulled out hair.

MOF controls key genes for skin development by regulating mitochondrial and ciliary functions.

Skin cell types develop when specific genes are turned on by removing certain chemical tags from DNA.