August 2001 in “Dermatologic Surgery” This study found that using the KNU implanter for follicular unit transplantation resulted in a high survival rate of 92% at 6 months, regardless of whether one-hair or two-hair units were used.
June 2020 in “Applied sciences” This study introduced a semi-automatic hair follicle implanter that can reduce surgery time and fatigue for both patients and surgeons, with effectiveness demonstrated in animal and clinical trials.
July 2023 in “Clinical, Cosmetic and Investigational Dermatology” This study explains surgical techniques for hair transplantation using the sharp implanter method, emphasizing 11 key principles that optimize efficiency and precision, and reports high graft survival and natural hair density when these principles are followed.
June 2017 in “Advances in intelligent systems and computing” This study developed a prototype pneumatic dual-cell implanter that successfully stacked and implanted cells in tests, reducing hand burden for operators, which may improve alopecia treatments compared to traditional hair transplantation.
6 citations
,
July 2013 in “Molecular Imaging” This study successfully used noninvasive bioluminescence imaging to monitor hair generation in vivo after transplanting hair follicle stem cells in mice.
6 citations
,
January 2010 in “Actas Dermo-Sifiliográficas” This review covers the current procedure for follicular unit hair transplantation, noting that recent advancements have made the results natural and undetectable, but it presents no new experimental findings.
4 citations
,
May 2017 in “Hair transplant forum international” This article discusses the historical development and recent rejuvenation of implanter pens in hair restoration surgery and does not present new research findings.
14 citations
,
September 2018 in “Biochemical and Biophysical Research Communications” This study suggests that co-culturing human outer root sheath cells with human dermal papilla cells can restore their ability to induce hair growth by altering gene expression through paracrine signaling.
1 citations
,
January 2021 in “Dermatological reviews” This review discusses advancements in hair transplantation surgery and its capacity to achieve excellent results with trained surgeons; it does not report new clinical findings.
13 citations
,
July 2019 in “Journal of Dermatological Science” This study suggests that 3D spheroid cultivation of dermal papilla cells can restore their hair-inductive capabilities, which are lost in 2D-cultured cells.
1 citations
,
January 2019 in “Annals of dermatology/Annals of Dermatology” STAT5 is crucial for hair growth in 3D cultured human dermal papilla cells.
16 citations
,
January 2018 in “Biochemical and Biophysical Research Communications” In this study, researchers established five new immortalized human dermal papilla cell lines from a male with androgenetic alopecia, which may serve as valuable tools for hair research.
5 citations
,
October 2020 in “Frontiers in Cell and Developmental Biology” This study found that the trichogenicity of cultured human outer root sheath follicular keratinocytes decreased with longer cultivation periods and was significantly influenced by the expression of the transcription factor FOXA2.
6 citations
,
July 2012 in “Experimental Dermatology” In this study, treatment with human follicular keratinocyte-conditioned media improved the trichogenicity of cultured dermal cells by activating key signalling pathways, suggesting its potential use in cell therapy for hair loss.
4 citations
,
April 2015 in “Experimental Dermatology” This study found that OVOL1-regulated genes, particularly Fst and SFRP1, significantly affect the hair-inducing capacity of neonatal mouse dermal cells.
16 citations
,
April 2009 in “Dermatologic Surgery” The place where hair is transplanted can change its growth rate and length but not its thickness.
4 citations
,
December 2007 in “Dermatologic Surgery” This study found that using 3% hydrogen peroxide for surgical wound care during hair restoration did not significantly affect the survival rate of hair grafts compared to normal saline.
September 2007 in “Dermatologic Surgery” This study found that using 3% hydrogen peroxide for surgical wound care during hair restoration surgery did not significantly impact the survival rate of hair grafts compared to normal saline.
58 citations
,
March 2019 in “Experimental Dermatology” This study suggests that exosomes derived from dermal papilla cells, especially those cultured in three dimensions, promote hair growth and regeneration by enhancing follicular cell activity.
17 citations
,
May 2010 in “Journal of Dermatological Science” This study found that erythropoietin promotes hair growth by stimulating dermal papilla cells with functional erythropoietin receptors, enhancing hair shaft elongation and anagen phase in cultured human hair follicles and in mice.
5 citations
,
October 2016 in “Experimental Dermatology” This study found that activin A signaling is crucial for hair follicle neogenesis in human dermal papilla 3D cultures combined with mouse epidermal cells.
13 citations
,
July 2022 in “Frontiers in cell and developmental biology” This review discusses the potential of cell-derived nanovesicles as innovative treatment strategies for hair growth and provides no new clinical results; the authors emphasize the need for further understanding of their mechanisms.
15 citations
,
December 2007 in “Dermatologic Therapy” This review discusses past hair transplantation techniques for androgenic alopecia and current research to improve results, but it reports no new clinical outcomes.
2 citations
,
September 2024 in “Aesthetic Plastic Surgery” This abstract provides guidance on where to find authors' assigned levels of evidence for articles in the journal, but it does not report any research findings from a specific study.
December 2016 in “Journal of Dermatology and Dermatologic Surgery” In this study, the Instant Follicular Hair Unit Transplant technique demonstrated superior hair growth compared to conventional FUE in patients with androgenetic alopecia, although it requires a steeper learning curve for surgeons.
75 citations
,
August 2011 in “Journal of Investigative Dermatology” This study found that cultured human dermal papilla cells formed into three-dimensional spheres have an increased ability to induce hair follicles from mouse epidermal cells compared to two-dimensional cultures.
10 citations
,
January 2016 in “Annals of Dermatology” This article discusses the factors contributing to acne and reports no new findings, focusing on the role of sebaceous lipids and associated processes.
8 citations
,
October 2018 in “Applied sciences” This study found that alginate spheres maintain dermal papilla cells in a dormant state with increased trichogenecity, suggesting potential benefits for cell therapy in androgenic alopecia.
5 citations
,
October 2024 in “International Journal of Biological Sciences” This study found that a specific fragment of AIMP1, secreted by hair follicle stem cells, activated dermal papilla cells, leading to enhanced hair regrowth and maintenance in mice.
4 citations
,
May 2012 in “Tissue Engineering and Regenerative Medicine” This study demonstrated the potential of epithelial cell scaffolds fabricated with various materials for effective hair regeneration, highlighting their promising application in tissue engineering for alopecia treatment.