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The guideline recommends mental health involvement in diagnosing gender identity disorder and outlines hormone and surgical treatment protocols, emphasizing safety, informed consent, and long-term monitoring.

Lgr5 is a marker for active, long-lasting stem cells in mouse hair follicles.

Hair follicles can regrow in wounded adult mouse skin using a process like embryo development.

This review summarizes fundamental concepts and recent advancements in hair follicle biology, including insights from mouse models into broader molecular and cellular processes relevant to regeneration and development.

This study found that deleting the ATR gene in adult mice led to rapid onset of age-related traits such as hair graying and osteoporosis through reduced regenerative capacity.

This review discusses the role of androgens in the progression of cardiovascular disease and explores novel therapeutic targets without reporting new clinical results.

This study observed that among a cohort of reproductive-aged women in the U.S., the prevalence of PCOS was about 4.0%, with no significant racial differences between White and Black women.

This review discusses the complex mechanisms regulating skin immunity to balance host defense with inflammation, but reports no new findings.

This study found that Tcf3 and Lef1 differently regulate cell differentiation in multipotent skin stem cells, with Tcf3 promoting follicle-like features and Lef1, when modified, promoting sebocyte differentiation.

This article discusses the clinical presentation, histopathologic findings, and pathogenesis hypotheses of vitiligo without reporting new clinical results.

This study found that VEGF significantly enhances perifollicular vascularization during the hair growth phase, accelerating hair regrowth and increasing follicle and hair size, while its inhibition retards hair growth.

This review details the expression and diverse functions of melatonin receptors in non-neural tissues and reports no new clinical findings, emphasizing their potential as therapeutic targets across various physiological and pathological processes.

This study found that intradermal adipocyte lineage cells in mice are necessary and sufficient to activate follicular stem cells, highlighting their role in regulating skin stem cell activity.

This study found that the prevalence of polycystic ovary syndrome was 6.5% in a minimally biased sample of Caucasian women from Spain.

This review discusses manipulating the stem cell niche as a strategy in regenerative medicine to repair damaged tissues, highlighting the potential benefits and challenges but reporting no new results.

This review discusses the discovery and potential therapeutic uses of proteasome inhibitors across various diseases, including cancer and autoimmune conditions, but does not present new clinical data.

This review discusses the roles of key developmental signaling pathways in mammalian skin repair compared to skin development, and suggests these insights could lead to better wound healing therapies, but it reports no new findings.

This paper reviews the diagnostic criteria, etiological factors, and treatment approaches for PCOS, highlighting the importance of considering metabolic issues such as insulin resistance and obesity, but reports no new findings.

This paper discusses the role of steroid sulfatase in hormone-dependent tumors and highlights the development of potent inhibitors, noting the commencement of a phase I trial for one inhibitor in postmenopausal breast cancer patients.

This review discusses the role of keratins in epithelial cell stress protection and cancer, highlighting their potential as multifunctional regulators and diagnostic markers, without presenting new research findings.

This perspective suggests that browning agents may not directly enhance UCP1 expression in white adipose tissue but instead induce browning through increased heat loss, prompting thermogenesis to compensate.

This review focuses on coumarin analogs with potential antibreast cancer activities but reports no new clinical results, highlighting their mechanisms of action and structure-activity relationships.

This article highlights the versatility and potential of alginate and its derivatives in tissue engineering applications, discussing their properties, modification techniques, and various uses in enhancing tissue healing, bone regeneration, and cell growth.

This study found that corporate social responsibility can enhance consumer perceptions of product performance, especially when viewed as motivated by genuine benevolence rather than self-interest.

This study reports the first instance of skin autotomy in mammals, specifically in African spiny mice, and suggests they may possess a greater regenerative capacity than previously understood, possibly offering insights for regenerative medicine.

This review discusses the relationship between polycystic ovary syndrome and cardiovascular risk, noting a possible adverse impact on risk profiles and subclinical atherosclerosis but no clear increase in premenopausal cardiovascular events; it presents no new clinical results.

This study developed molecular signatures for dermal papilla cells and their niche, uncovering novel signaling regulators and genes linked to hair disorders, which may inform future hair development research.

This review discusses the role of DHEA in intracrinology, highlighting its impact on breast and prostate cancer treatment and potential as a menopause therapy, but reports no new research findings.

This review discusses the biology and development of skin melanocytes, but reports no new clinical findings.

This document extends previous recommendations by the National Lipid Association for managing dyslipidemia, focusing on lifestyle therapies, special patient groups, and strategies to enhance adherence and patient outcomes.