79 citations
,
October 2015 in “Journal of Dermatological Treatment” This review assesses the use of platelet-rich plasma in dermatology and concludes that while there may be modest benefits for certain conditions, more evidence is needed before it can be widely recommended.
77 citations
,
April 2016 in “Science Advances” Researchers created a fully functional, bioengineered skin system with hair from stem cells that successfully integrated when transplanted into mice.
76 citations
,
April 2013 in “PLoS ONE” The researchers reported that reactive oxygen species regulate the stress-induced SP-Mast cell pathway, which might support using antioxidants to treat stress-related hair loss.
70 citations
,
April 2016 in “Experimental Dermatology” In this study, oral tofacitinib treatment led to significant hair regrowth and changes in skin and blood biomarkers in a patient with alopecia areata.
69 citations
,
January 2020 in “Veterinary World” This review examines factors influencing dermatophyte infection in companion animals, focusing on prevalence, clinical signs, pathogenesis, immune response, and the impact of cortisol and cytokines, but reports no new clinical results.
66 citations
,
May 2012 in “Scientific Reports” This study demonstrated that bioengineered hair follicles reconstituted from embryonic skin cells and transplanted into hosts can restore physiological hair functions, suggesting potential applications for treating alopecia.
64 citations
,
January 2004 in “American journal of clinical dermatology” This review describes various types of folliculitis based on their causes, clinical manifestations, and treatments, but reports no new clinical results.
59 citations
,
August 2003 in “Phytotherapy Research” This study found that a 70% methanol extract from red ginseng stimulated hair growth in mouse vibrissal follicles, suggesting its bioactive components, particularly certain ginsenosides, may promote hair growth.
55 citations
,
May 2014 in “Journal of feline medicine and surgery” This review discusses feline dermatophytosis and emphasizes the importance of early detection and appropriate treatment, but it reports no new clinical results.
54 citations
,
September 2000 in “Archives of dermatology” In this study, 95% of respondents reported severe hair breakage or loss after using the Rio Hair Naturalizer System, with many experiencing significant and lasting hair loss.
45 citations
,
November 2017 in “Biomaterials” This study demonstrated a method for large-scale preparation of self-sorted hair follicle germs in vitro, which successfully generated hair follicles when transplanted into the skin of nude mice.
44 citations
,
October 2017 in “Scientific Reports” This study found that far-infrared radiation preconditioning significantly enhanced the proliferation, survival, and migration of bone marrow-derived stem cells in vitro, indicating potential therapeutic benefits for cardiac ischemia treatment.
44 citations
,
April 2017 in “Genes & development” This study identified hair shaft progenitors in the matrix that regulate hair growth and pigmentation by creating a niche dependent on stem cell factor, implicating KROX20+ cells in these processes.
41 citations
,
December 2008 in “Journal of the American Academy of Dermatology” This review discusses fixed drug eruption (FDE) potentially linked to finasteride and emphasizes dermatologists' need to recognize its possible occurrence due to the drug's widespread use, but reports no new clinical results.
39 citations
,
July 2013 in “Journal of dermatological science” This study found that microRNA levels in hair shafts were significantly decreased in scleroderma patients compared to normal subjects, suggesting they may serve as effective biomarkers.
38 citations
,
July 2010 in “Clinical, cosmetic and investigational dermatology” This review discusses systemic antifungal treatments for tinea capitis in children, noting that newer agents like terbinafine and itraconazole require shorter courses than the traditional griseofulvin, but may be more costly.
37 citations
,
June 2018 in “Clinical and Experimental Medicine” This study found that patients with alopecia areata had significant systemic inflammation and vitamin D deficiency, with both conditions more pronounced as disease severity increased.
36 citations
,
December 2012 in “Dermatologic Surgery” Injecting platelet-rich plasma (PRP) can increase hair growth rate and density in male pattern baldness.
36 citations
,
June 2018 in “Journal of Dermatology” This article updates Japanese guidelines for diagnosing and treating male and female-pattern hair loss, recommending specific drugs and therapies while advising against certain treatments for female-pattern hair loss.
29 citations
,
March 2016 in “Cell cycle/Cell cycle (Georgetown, Tex. Online)” This study observed that isoproterenol directs hair-follicle-associated pluripotent stem cells to differentiate into cardiac muscle cells in large numbers, forming tissue sheets of beating heart muscle cells in culture.
27 citations
,
August 2006 in “Laboratory Investigation” In this study, the combination of SCF and ET-1 was found to significantly enhance skin pigmentation and melanin content in human skin xenografts on SCID mice compared to either treatment alone.
27 citations
,
July 1982 in “British Journal of Dermatology” The antiandrogen 11α-hydroxyprogesterone effectively reduces skin oil and cholesterol when applied to the skin.
26 citations
,
October 2018 in “Clinical & Translational Oncology” This review outlines dermatological toxicities associated with targeted cancer therapies and immunotherapies, emphasizing the need for collaborative management by oncologists and dermatologists but reports no new clinical findings.
26 citations
,
January 1994 in “Hormone and Metabolic Research” This study found that one year of antiandrogen treatment with spironolactone significantly decreased bone mineral density in young women with androgen excess.
25 citations
,
January 2022 in “Endocrine journal” This study suggests that hormonal changes may contribute to the persistent symptoms of long COVID, with specific patterns observed in serum hormone levels related to fatigue and sensory dysfunction.
25 citations
,
November 2015 in “Journal of Ethnopharmacology” This study found that Cacumen platycladi extract significantly promoted hair growth and reduced dihydrotestosterone levels by inhibiting 5α-reductase activity in an androgen-sensitive mouse model.
25 citations
,
December 1992 in “Seminars in cell biology” This review discusses how epidermal Langerhan's cells and dermal cells may influence keratinocyte environments, potentially aiding in the formation of stem cell niches and cellular variety in the basal layer, without providing novel results.
25 citations
,
July 2017 in “Journal of Stomatology, Oral and Maxillofacial Surgery” This review suggests that PRP injections may be effective in promoting hair regrowth, reducing hair loss, and increasing hair thickness in patients with androgenic alopecia.
23 citations
,
March 2019 in “Journal of Essential Oil Research” This study found a strong correlation between antioxidant activity and phenolic content in rosemary, influenced by bioclimatic and seasonal factors in different stages of Tunisia.
22 citations
,
June 1993 in “Calcified Tissue International” This study found that women with hyperandrogenic amenorrhea do not show reduced bone mineral density compared to controls, indicating they may be protected from osteopenia.