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Too much AKR1C3 enzyme causes resistance to finasteride by increasing testosterone.

The document concludes that careful design of genetic fate mapping experiments is crucial for accurate cell lineage tracing in mice.

The research explains how a human enzyme binds and processes its substrate, which could relate to its role in biological functions and hair loss.

Some vitamin D analogs can thicken skin and reduce pore size like a common acne treatment, with one analog also affecting skin growth factors.

A specific DNA sequence caused hair loss in male mice by activating immune cells and increasing a certain immune signal.

Activating Notch signaling can kill basal cell carcinoma cells.

Melasma's causes include genetics, sun exposure, hormones, and oxidative stress, and understanding these can help create better treatments.

Certain genes and pathways are linked to the production of finer and denser wool in Hetian sheep.

Melatonin helps hair grow by activating a specific signaling pathway.

Hair follicle development in cashmere goats involves dynamic changes in proteins and metabolites, with key roles for oxytocin, MAPK, and Ca2+ pathways.

Riboflavin 5′-phosphate (FMN) shows potential for treating androgen-related conditions but may be limited in treating prostate cancer.

The human scalp hair bulb contains different types of melanocytes with varying abilities to produce melanin.

Certain gene variations and different levels of BDNF and CRH hormones are linked to vitiligo.

RANKL causes lymph nodes to grow by making certain cells multiply.

Mice without the vitamin D receptor are more prone to UV-induced skin tumors.

Vitamin D and its receptor may help prevent skin cancer.

Overactivating Hedgehog signaling makes hair follicle cells in mice grow hair faster and create more follicles.

OR2AT4 helps reduce aging and cell damage in human skin cells.

TLR2 helps control hair growth and regeneration, and its reduction with age or obesity can impair hair growth.

Hair color is determined by melanin produced and transferred in hair follicles.

Alopecia areata can be reversed by JAK inhibitors, promoting hair regrowth.

Innate lymphoid cells help control skin bacteria by regulating sebaceous glands.

Psoriasis may be chronic because it lacks certain immune system controls that prevent overreaction.

A new mutation in the ST14 gene broadens the understanding of ichthyosis-hypotrichosis syndrome.

Higher levels of certain DNAs in blood may indicate hair follicle damage in alopecia areata patients.

Mannan oligosaccharides improve raccoon dogs' fur quality and overall health.

BAY 43-9006 helps control kidney cancer growth but doesn't significantly increase overall survival.

The PDGF/PDGFR pathway is a potential drug target with mixed success in treating various diseases, including some cancers and fibrosis.

The three estrogen receptor genes are highly expressed in zebrafish neuromasts during development.

LEF1 interacts with Vitamin D Receptor, affecting hair follicle regeneration and this could be linked to hair loss conditions.