research Characteristics of KRT80 and Its Roles in Neoplastic Diseases
KRT80 may worsen cancer by increasing growth and spread, but its full effects on treatment and outcomes need more research.
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900-930 / 1000+ results research 3D Spheroid Human Dermal Papilla Cell as an Effective Model for the Screening of Hair Growth Promoting Compounds: Examples of Minoxidil and 3,4,5-Tri-O-Caffeoylquinic Acid (TCQA)
3D cell cultures are better for testing hair growth treatments than 2D cultures.
research Clinical Translation of Microbiome Research in Alopecia Areata: A New Perspective
Further research is needed to understand how the microbiome affects hair loss in Alopecia Areata.
research From Hair to Colon: Hair Follicle-Derived MSCs Alleviate Pyroptosis in DSS-Induced Ulcerative Colitis by Releasing Exosomes in a Paracrine Manner
Hair follicle stem cells can help treat ulcerative colitis in mice by releasing beneficial exosomes.
research Reawakening GDNF's Regenerative Past in Mice and Humans
Activating the GDNF-GFRα1-RET signaling pathway could potentially promote skin and limb regeneration in humans and could be used to treat hair loss and promote wound healing.
research Whole Blood Transcriptome Profiling Identifies Candidate Genes Associated With Alopecia in Male Giant Pandas
Researchers found genes linked to hair loss in male giant pandas.
research Thyroid Hormone Receptor Agonist Promotes Hair Growth in Mice
TDM10842, a thyroid hormone receptor activator, was found to effectively promote hair growth in mice.
research Addressing Androgenetic Alopecia: A Complex Disorder with a Multilateral Treatment Strategy
Treating hair loss effectively may require a multi-sided approach, using different treatments together, and topical treatments could be more effective and safer than oral ones.
research Computational Drug Repositioning in Cardiorenal Disease: Opportunities, Challenges, and Approaches
The article explores computational drug repositioning for cardiorenal diseases, emphasizing its potential to find new uses for existing drugs through various computational methods like network-based, pathway-based, and knowledge graph-based approaches. These methods leverage data from drug targets, molecular pathways, and real-world sources like electronic health records to identify new drug-disease connections. The document highlights successful repositioning examples, such as GLP1 agonists and metformin, and discusses challenges like patentability and regulatory hurdles. It concludes that drug repositioning is a promising strategy for rapidly developing new treatments, particularly for rare diseases, despite challenges in funding and trial phases.
research Understanding the Intricate Pathophysiology of Psoriasis and Related Skin Disorders
Psoriasis involves immune and genetic factors, and understanding these can improve treatments.
research Signal Integrator Function of CXXC5 in Cancer
CXXC5 can both suppress and promote cancer, making it a complex target for treatment.
research Caffeine as an Active Molecule in Cosmetic Products for Hair Loss: Its Mechanisms of Action in the Context of Hair Physiology and Pathology
Caffeine may help with hair loss, but more research is needed to confirm its effectiveness.
research Pathogenesis and Management of TRPV3-Related Olmsted Syndrome
EGFR and mTOR inhibitors may help manage Olmsted syndrome symptoms.
research New Plant Extracts Exert Complementary Anti-Hair Loss Properties in Human In Vitro and Ex Vivo Models
The plant extracts may help treat hair loss by promoting hair growth and reducing DHT levels.
research Comparison of In Vitro Hair Growth Promotion and Anti-Hair Loss Potential of Thai Rice By-Product from Oryza Sativa L. Cv. Buebang 3 CMU and Sanpatong
Et-BB3-CMU rice bran extract may be a promising natural option for promoting hair growth and preventing hair loss.
research Application of Multi-Omics Techniques to Androgenetic Alopecia: Current Status and Perspectives
Multi-omics techniques help understand the molecular causes of androgenetic alopecia.
research Hair Growth-Promoting Effect of the Coffee Bean Residue Extract on Hair Follicle Dermal Papilla Cells via the Activation of Autophagy
Coffee bean residue extract helps hair growth by activating cell processes.
research Autophagy Dysfunction: The Kernel of Hair Loss?
Manipulating cell cleanup processes could help treat hair loss.
research Role of Dermal Factors Involved in Regulating the Melanin and Melanogenesis of Mammalian Melanocytes in Normal and Abnormal Skin
Dermal factors are crucial in regulating melanin production in skin.
research Pathogenesis of Alopecia Areata and Vitiligo: Commonalities and Differences
Alopecia areata and vitiligo share immune system dysfunction but differ in specific immune responses and affected areas.
research Progress on the Mechanism of Natural Products Alleviating Androgenetic Alopecia
Natural products might be safe, effective, and affordable treatments for hair loss.
research Genetics and Epigenetics of Polycystic Ovary Syndrome
Genes and epigenetic changes are important in the development of Polycystic Ovary Syndrome.
research Toward a Unifying Hypothesis for Redesigned Lipid Catabolism as a Clinical Target in Advanced, Treatment-Resistant Carcinomas
Targeting lipid metabolism can help treat advanced, resistant cancers.
research Whole-Genome Resequencing Reveals Selection Signal Related to Sheep Wool Fineness
Genes linked to wool fineness in sheep have been identified.
research Potential Natural Products Regulation of Molecular Signaling Pathway in Dermal Papilla Stem Cells
Certain natural products may help stimulate hair growth by affecting stem cell activity in the scalp.
research The Potential Role of Exosomes in Aesthetic Plastic Surgery: A Review of Current Literature
Exosomes may improve skin, scars, hair growth, and fat grafts in plastic surgery, but more research is needed.
research CAQ Corner: Basic Concepts of Transplant Immunology
The document explains how the immune system reacts to organ transplants and the treatments used to prevent rejection.
research Pilosebaceous Follicles: Structure, Biochemistry, and Function
Sebaceous glands play a key role in skin health and conditions like acne.
research Platelet-Rich Plasma: Alopecia Areata and Autoimmune Destruction of the Hair
PRP is a promising treatment for autoimmune hair loss but its exact workings are not fully understood.
research Anti-Aging Medicine for Hair
Early anti-aging hair treatments should focus on anti-inflammatory agents and promoting healthy hair growth cycles.