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TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.

Melatonin is important for skin health and protection, and can be made by the skin or applied to it.

The Rotterdam Study aims to understand various diseases in older adults.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

The guidelines suggest a detailed approach to diagnosing and treating lupus, with a focus on regular check-ups, personalized medicine, and a range of drug options for different cases.

Minoxidil and finasteride treat hair loss in men, while minoxidil treats hair loss in women.

Iron deficiency may be related to hair loss, but there's not enough evidence to recommend iron screening or supplements for all hair loss patients.

Early diagnosis and treatment, using finasteride, minoxidil, or hair transplantation, improves hair loss outcomes.

Lifestyle changes can improve body composition, excess male hormone levels, and insulin resistance in women with PCOS.

Men are more likely to have severe COVID-19 cases and fatalities than women due to factors like lifestyle, aging, and biological differences.

Biotinidase deficiency has various symptoms and can be treated with biotin supplements.

Opioid painkillers can cause many side effects, including breathing problems and addiction, but are generally considered safe when used properly.

The PDGF/PDGFR pathway is a potential drug target with mixed success in treating various diseases, including some cancers and fibrosis.

Special fiber materials boost the healing properties of certain stem cells.

Some medicinal plants can help heal wounds and may lead to new treatments.

Hormone treatments for transgender individuals generally improve mental health and physical transition, with some health risks that require medical supervision.

Blocking COX, especially COX-2, in the skin can reduce inflammation and pain and may help prevent skin cancer.

Some skin medications are safe during pregnancy and breastfeeding, but others can harm the baby and should be avoided.

Lupus affects the body and skin, causing joint pain and skin issues that can be treated with steroids and antimalarial drugs.

The document concludes that specific cells are essential for hair growth and more research is needed to understand how to maintain their hair-inducing properties.

Taking selenium supplements during chemotherapy may help reduce side effects and improve health markers in ovarian cancer patients.

TRP channels in the skin are important for sensation and health, and targeting them could help treat skin disorders.

Hair follicles produce and respond to melatonin, affecting hair growth and sensitivity to estrogen.

Vitamin D has potential benefits for cancer prevention, heart health, diabetes, obesity, muscle function, skin health, and immune function, but clinical results are mixed and more research is needed.

Fibroblast growth factor receptor signaling controls cell development and repair, and its malfunction can cause disorders and cancer, but it also offers potential for targeted therapies.

Potassium channel openers are effective in treating heart conditions, high blood pressure, pulmonary diseases, bladder issues, and hair loss, but more selective drugs are needed.

Minoxidil effectively treats hair loss, but use cautiously and monitor side effects.

Scientists turned rat thymus cells into stem cells that can help repair skin and hair.

The research found that Atypical Progeroid Syndrome has unique symptoms and is not caused by the buildup of a certain mutant protein.

Testosterone treatment in trans men increases body and facial hair and may lead to hair loss over time, but severe skin issues are rare.