1 citations
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September 2017 in “Elsevier eBooks” Diuretics help the body get rid of excess salt and water by acting on the kidneys in different ways.
1 citations
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August 2022 in “Frontiers in Physiology” This study suggests that finasteride may help alleviate high-fat diet-induced kidney damage in mice by reducing TMAO synthesis and regulating gut microbiota.
May 2025 in “Cermin Dunia Kedokteran” This study highlights that early detection and tailored treatment based on kidney biopsy classification are crucial in managing lupus nephritis to prevent progression to end-stage kidney disease, with a focus on saving nephron cells.
19 citations
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July 1983 in “American Journal of Kidney Diseases” Minoxidil lowers blood pressure in kids with kidney issues, but use carefully due to side effects.
November 2022 in “Arab Gulf Journal of Scientific Research” This review discusses the potential clinical benefits and functional properties of taurine as a conditionally essential amino acid, noting its presence in energy drinks, but reports no new experimental results.
October 2024 in “Journal of the American Society of Nephrology” This study found that in a large cohort of chronic kidney disease patients, nonprogression or regression of the disease was more common than progression or kidney failure, especially with advancing age.
October 2013 in “Journal of Investigative Dermatology” Collagen VII helps skin heal and stay strong, sirolimus may lower skin cancer risk in kidney transplant patients, high-molecular-mass hyaluronan helps naked mole rats resist cancer, dermal γδ T cells aid in hair growth in rodents, and overexpression of IL-33 in mouse skin causes itchiness, offering a model for studying allergic inflammation treatments.
October 2025 in “Benha Veterinary Medical Journal” In this study, the researchers reported that both dandelion and safflower extracts protected against liver and kidney damage caused by thioacetamide in rats, with safflower being more effective than both silymarin and dandelion.
This study reported that severe hypothyroidism in two pediatric patients was associated with transient liver and kidney dysfunction, which resolved after beginning levothyroxine treatment.
845 citations
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February 2001 in “The Journal of Clinical Endocrinology & Metabolism” This study identified the presence of the enzyme 1 alpha-hydroxylase in various extrarenal tissues, suggesting its potential role in modulating vitamin D function in peripheral tissues.
19 citations
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March 2008 in “Nature clinical practice endocrinology & metabolism” A combined drug and laser treatment improved hirsutism in a PCOS patient, also enhancing her heart health and requiring regular liver and kidney checks.
6 citations
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March 2018 in “Proceedings - Baylor University. Medical Center” This case report describes a patient with sarcoidosis who experienced severe symptomatic hypercalcemia, scarring alopecia, and acute-on-chronic kidney failure.
January 2025 in “Indian Journal of Experimental Biology” In this study, mice orally exposed to carbon-based nanoparticles for 30 days showed significant liver and kidney changes, behavioral alterations, and physiological disturbances, suggesting potential severe health risks due to the nanoparticles' slow clearance and formation of reactive oxygen species.
In this study, testosterone treatment was found to increase blood pressure in rats, potentially through mechanisms involving sodium and water retention in the kidneys and changes in specific gene expressions in the brain.
81 citations
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November 2012 in “Journal of the National Cancer Institute” This study found that FLCN deficiency in mice muscles led to increased mitochondrial biogenesis and a metabolic shift towards oxidative phosphorylation, with a similar advantage observed in FLCN-null kidney cancer cells.
48 citations
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February 2013 in “Molecular and Cellular Endocrinology” This review discusses the presence of the StAR protein in 17 non-classical steroidogenic tissues, suggesting that advanced detection methods are needed for a complete understanding of its functions in these tissues.
36 citations
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July 1987 in “Journal of toxicology and environmental health” This study found that rats fed diets with heated corn or peanut oil showed signs of toxicity, including liver and kidney weight increases, diarrhea, and ceased spermatogenesis, compared to those consuming fresh oils.
17 citations
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April 2007 in “Kidney international” This study found that 1,25 dihydroxyvitamin D3 significantly increased the expression and activity of vasculoprotective natriuretic peptide receptor-A in cultured inner medullary collecting duct cells, suggesting a potential mechanistic role in cardiovascular and renal benefits.
February 2018 in “The Journal of Sexual Medicine” In this animal study, finasteride exposure led to impaired spermatogenesis in rats, while the novel compound DA-9401, derived from three medicinal herbs, demonstrated potential in improving sperm parameters and reducing testicular apoptosis when used alone or with finasteride.
This case report describes a 21-year-old woman with systemic lupus erythematosus who developed lupus nephritis in the context of thrombotic microangiopathy, including a rare presentation of cryoglobulin-like thrombi.
86 citations
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June 2018 in “Cochrane library” This review update suggests that mycophenolate mofetil may increase complete disease remission in proliferative lupus nephritis compared to intravenous cyclophosphamide, but with low certainty of evidence.
40 citations
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November 2009 in “Experimental Dermatology” This review discusses the role of the mineralocorticoid receptor in skin biology, highlighting its potential involvement in keratinocyte and hair physiology, and proposes it may affect the side effects of glucocorticoid use.
1 citations
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January 2021 in “Journal of biological chemistry/The Journal of biological chemistry” This study found that loss of the folliculin protein delays transferrin receptor recycling, leading to iron deficiency and suggesting a role in the mechanisms of Birt-Hogg-Dubé syndrome.
June 2023 in “Nephrology Dialysis Transplantation” In this case report, researchers highlighted two instances of oxalate nephropathy secondary to enteric hyperoxaluria following small bowel surgeries, emphasizing the need to consider this condition in patients with unexplained renal decline and a history of bowel surgery due to its typically poor prognosis.
24 citations
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October 2017 in “Biomolecules” This review discusses the broader roles of angiogenic factors, like VEGFs and FGFs, beyond angiogenesis, highlighting their involvement in various biological and pathological processes.
May 2021 in “Journal of the Endocrine Society” This case report describes severe hypothyroidism exacerbated by nephrotic syndrome in a 62-year-old woman, with a diagnosis of membranous nephropathy linked to significant proteinuria.
May 2016 in “Journal of pediatric nursing” This case report highlights the need to consider complementary and alternative medicine use in endocrine evaluations, as stopping lavender oil use coincided with normalization of a concerning lab finding in a girl with precocious puberty signs.
75 citations
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February 2017 in “Aging” This study found that treating mtDNA mutator mice with the antioxidant SkQ1 delayed aging traits and extended their lifespan, potentially by alleviating mitochondrial dysfunction caused by reactive oxygen species.
17 citations
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December 2006 in “Gene Expression Patterns” This study reports that the mouse Scube3 gene is expressed in various tissues during embryonic development, including the neural tube, limb buds, developing tooth, hair follicle, and skeletal regions.
2 citations
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December 2022 in “Journal of Biochemistry and Molecular Biology” This review discusses the development and potential applications of organoids for human disease modeling and regenerative medicine but reports no new experimental results.