July 2018 in “Elsevier eBooks” This study highlights lichen planopilaris as a form of scarring hair loss with symptoms like shedding and itching, and notes successful treatment options such as topical and oral antiinflammatory medications to preserve hair follicles by early intervention.
24 citations
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February 2023 in “BMC Complementary Medicine and Therapies” This study found that Forsythiaside A may protect against sepsis-induced acute kidney injury in mice by reducing inflammation and apoptosis through modulation of ER stress responses.
1 citations
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November 2023 in “Journal of ovarian research” In this study involving rats with letrozole-induced polycystic ovary syndrome, Agaricus subrufescens significantly reduced blood glucose, total cholesterol, testosterone levels, and renal markers, suggesting its potential protective effects on both metabolic and reproductive parameters.
September 2024 in “Medicine” This study found that alopecia areata and asthma are linked to graft dysfunction, while primary sclerosing cholangitis presents as heterogeneous, without any pleiotropy or heterogeneity in other autoimmune diseases assessed.
26 citations
,
January 2020 in “Przegląd Menopauzalny” This review discusses the role of androgens in menopausal women's health, highlighting symptoms of both hyperandrogenemia and androgen deficiency, but reports no clinical results.
5 citations
,
December 2005 in “Clinical Techniques in Equine Practice” This review discusses how skin lesions and haircoat changes in adult horses can indicate systemic diseases, emphasizing the need for veterinary evaluation, and reports no new clinical findings.
14 citations
,
May 2022 in “Frontiers in Endocrinology” This study found that lower serum testosterone levels were significantly associated with an increased prevalence of kidney stones in men over 40, but not in those aged 20–40.
12 citations
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November 2021 in “Journal of Clinical Medicine” This study reported that 70.1% of kidney transplant recipients experienced persistent symptoms of post-COVID-19 syndrome six months after infection, with older patients and those with more comorbidities being more affected.
11 citations
,
January 2020 in “World Journal of Traditional Chinese Medicine” This study used a glucocorticoid-injection model to mimic kidney-yang deficiency syndrome and reported symptoms related to hormonal imbalances in the hypothalamic-pituitary-target gland axes.
3 citations
,
January 2017 in “Journal of cardiovascular pharmacology” This article discusses the challenges in hypertension management, emphasizing the need to reconsider the use of minoxidil and address excess dietary sodium and arteriolar hypertrophy, but reports no new clinical results.
1 citations
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August 2023 in “Diagnostics” This study observed that women with Polycystic Ovary Syndrome, particularly those with specific phenotypes, had a significantly higher risk of developing kidney stones compared to healthy controls.
122 citations
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December 2022 in “International Journal of Molecular Sciences” In this review, researchers discussed recent advances in nanotechnology for topical skin applications, highlighting how nanocarriers enhance skin penetration and targeting in treatments for diseases like melanoma and psoriasis, while acknowledging that the penetration mechanisms and health impacts of nanoparticles remain not fully understood.
April 2020 in “BMC endocrine disorders” This case report describes a 65-year-old woman with childhood-onset growth hormone deficiency who developed panhypopituitarism, including late-onset secondary hypoadrenocorticism, affecting her respiratory and renal function.
4 citations
,
May 2024 in “Biomolecules” This study examined connections between bioelements like Zn, Cu, and Mn in serum and bone tissue and hormone concentrations in men with and without erectile dysfunction, highlighting potential relationships that may help explain ED's etiology.
4 citations
,
February 2022 in “The Journal of Urology” This study found that depression, anxiety, and sleep disturbance were associated with male lower urinary tract symptoms, but these factors did not predict improvement after evaluation and treatment over time.
7 citations
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March 2022 in “The FASEB journal” This study observed that mice with a whole-body deficiency of Cystathionine-β-synthase developed severe hyperhomocysteinemia and related mild symptoms without increased mortality, indicating HHCy may not directly cause end organ damage.
131 citations
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September 2017 in “Molecular and Cellular Endocrinology” This article discusses the role of androgens in metabolic and reproductive health and reports no new experimental results; the focus is on androgen receptor activation by testosterone and 5α-dihydrotestosterone.
20 citations
,
July 1998 in “Annals of Clinical Biochemistry International Journal of Laboratory Medicine” This case study details a 56-year-old man with initial misdiagnosed Addison's disease who was later found to have hypogonadotrophic hypogonadism and secondary hypothyroidism.
4 citations
,
December 2019 in “Trials” This study aims to evaluate the effectiveness of YH0618 granules in preventing chemotherapy-induced hair loss in breast cancer patients through a randomized, double-blind, multi-center clinical trial, focusing on potential mechanisms related to kidney deficiency as understood in Chinese Medicine. Results are not yet reported.
23 citations
,
November 1986 in “Pediatrics” Minoxidil, when used with a diuretic and β-blocking agent, can safely lower blood pressure in most children with severe hypertension due to kidney disease, with minimal side effects.
3 citations
,
March 2024 in “iScience” This study found that long-lived proteins in mice, identified across various tissues, may be linked to neurodegenerative and cardiovascular diseases due to their low renewal rate and increased risk of damage.
1 citations
,
February 2020 in “Journal of the Canadian Association of Gastroenterology” This case report describes a rare occurrence of tacrolimus-induced atypical hemolytic uremic syndrome in a pediatric liver transplant patient, where discontinuation of tacrolimus resolved symptoms and re-initiation was later tolerated without recurrence.
December 2024 in “International Journal of Molecular Sciences” This study provides a comprehensive overview of human umbilical cord mesenchymal stem cell-derived extracellular vesicles (HUCMSC-EVs), suggesting their potential to combat aging and alleviate age-related disorders by rejuvenating multiple organs in animal models and discussing engineering strategies to harness their full anti-aging potential.
February 2023 in “Vaccines” This review discusses the potential impact of COVID-19 on the male reproductive system and highlights unanswered questions regarding its mechanisms and implications for men's health and fertility, reporting no new clinical results.
25 citations
,
November 2001 in “Kidney International” This study suggests that dihydrotestosterone plays a key role in the development of chronic allograft nephropathy, and inhibiting androgens may improve long-term kidney transplant outcomes.
87 citations
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March 2015 in “The EMBO Journal” This review discusses the plasticity of stem cell populations and their ability to switch between functions for tissue homeostasis and regeneration, emphasizing environmental and hormonal influences, and reports no new results.
38 citations
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January 2017 in “PPAR Research” This review discusses the role of PPAR-γ in the pathogenesis of primary cicatricial alopecia, including its involvement in lichen planopilaris and treatment trials using PPAR-agonists, and reports no new clinical results.
35 citations
,
February 2023 in “Biomolecules” This review explores the role of Granzyme B in autoimmune skin diseases and highlights its potential as a therapeutic target due to its involvement in impaired barrier function and inflammation.
34 citations
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February 2015 in “Frontiers in Cellular Neuroscience” This study identified new genes and compounds affecting hair cell survival during ototoxin exposure using the zebrafish model, potentially aiding in understanding and preventing hearing loss and balance disorders in humans.
20 citations
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August 2022 in “Frontiers in Immunology” This review discusses the role of fibroblasts in treating diabetic complications and wound healing, highlighting their potential as immunomodulatory factors but provides no new clinical results.