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Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.

Looking at skin can help find and treat serious diseases early.

Amenorrhea, or the absence of periods, should be evaluated by age 15 or within five years of early breast development, and is most commonly caused by conditions like polycystic ovary syndrome and hypothalamic amenorrhea.

The research suggests that autophagy-related genes might play a role in causing alopecia areata.

Dutasteride does not impair mental function in elderly men with enlarged prostate.

Juniperus plants contain compounds with potential for developing various medical treatments.

Eating less can slow aging and help keep stem cells healthy by cleaning out damaged cell parts.

Using systemic drugs as creams for skin conditions shows promise, but more research is needed to confirm their effectiveness and safety.

Some chemicals absorbed through the skin can cause serious health problems.

Spironolactone, a heart and liver drug, has new uses including cancer treatment, viral infection prevention, and skin condition improvement.

Patients with myotonic dystrophy often have skin problems that suggest early aging and vitamin D issues, and the severity of these problems is linked to their genetic condition and vitamin D levels.

The article concludes that correctly diagnosing systemic causes of hair loss requires a detailed clinical evaluation and a systematic diagnostic approach.

Coriander seed oil is safe for healthy adults at up to 600 mg per day.

Certain proteins and their receptors are more active during the growth phase of human hair and could be targeted to treat hair disorders.

Selective Androgen Receptor Modulators (SARMs) are drugs that can control the effects of androgens in different tissues, potentially having fewer side effects and promising for treating various conditions.

The document concludes that PK/PD modeling is important for determining the safe and effective dosages of drugs.

Chemotherapy and cytokine therapy can cause various skin reactions, including hair loss and hypersensitivity.

COVID-19 may harm male fertility and damage the reproductive system.

Patients with chronic renal failure on hemodialysis often have skin problems like dry skin, itching, and nail changes.

New treatments for enlarged prostate are being developed, some of which may be more effective than current medications.

Melatonin-loaded nanocarriers improve melatonin delivery and effectiveness for various medical treatments.

A new therapy sped up wound healing and reduced scarring in diabetic rats.

Certain genetic markers linked to reproductive potential were identified by their impact on a protein's ability to bind to genes.

Different diagnostic criteria greatly affect PCOS diagnosis rates in teenagers.

Indian women with PCOS from Delhi and Srinagar show different symptoms, with Delhi women having higher obesity and blood sugar issues, and Srinagar women showing more hair growth and testosterone levels.

The document concludes that "Dictamnus" has a rich cultural history and potential as a herbal medicine, warranting more research into its effects and safety.

FoxN1 overexpression in young mice harms immune cell and skin development.

COVID-19 and hypopituitarism (reduced pituitary gland function) are linked, with the latter's related health issues potentially worsening COVID-19 outcomes, and COVID-19 possibly increasing risk for pituitary complications.

Blocking enzymes that help the virus enter cells could be a promising way to treat COVID-19.

Exosomes are important for skin health and could help diagnose and treat skin diseases.