research Are STK11 Polymorphisms a Predictor of the Response to Metformin in Polycystic Ovarian Syndrome?
STK11 gene variations do not predict how well metformin will work for PCOS, but may affect hair loss and excess hair growth.
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research Steroidogenic Factor-1 Lineage Origin of Skin Lesions in Carney Complex Syndrome
Skin lesions in Carney complex are likely caused by a specific group of skin cells that promote pigment production due to a genetic mutation.
research Downstream Molecular Responses to Volatile Signaling in Roots
Plant roots respond to fungus smells by possibly using certain proteins and a plant hormone to change root growth, but more research is needed.
research Retinoids in Hair Disorders
Retinoids can both cause and treat different hair disorders.
research Novel Biallelic RIPK4 Mutations Cause Ectodermal Dysplasia with Cutaneous Syndactyly
New RIPK4 gene mutations were found to cause a type of skin and limb birth defect.
research Using the Frog Embryonic Epidermis as a Model to Study Desmosome Function During Development
Frog skin cells need the protein desmoplakin for proper development and cell layer formation.
research Selectively Targeting JAK1 or JAK3 Pathway Is Sufficient to Reverse Alopecia Areata
Blocking JAK1 or JAK3 helps reverse hair loss in a mouse model of alopecia areata.
research Modulating Aging and Aging-Related Symptoms Using Endogenous Small Molecules
A molecule called α-ketobutyrate was found to extend lifespan and improve aging-related symptoms in worms and mice by activating certain cellular pathways and may help develop anti-aging treatments for humans.
research Mixing the Old with the New: Drug Repurposing for Immune Deficiency in the Era of Precision Medicine and Pediatric Genomics
Using old drugs for new uses can help treat rare immune deficiencies.
research IL-9 Mediated Human Primary Keratinocytes Invasion Is Dependent on MLC Controlled Contractility and Independent of MMP Activity
IL-9 increases skin cell movement but decreases their ability to invade, and this effect is controlled by cell contractility, not by MMPs.
research Effect of Fermented Mackerel Oil on Hair Growth
Fermented mackerel oil was found to promote hair growth by activating certain cell signals and increasing cell growth.
research Pediatric Dermatology Photoquiz: A 14-Year-Old Boy with Abrupt-Onset Hair Changes
A 14-year-old boy was diagnosed with a rare hair condition that may lead to hair thinning and has no known effective treatments.
research Augmentation of HGF Signaling: Potential for Enhancing Hair Follicle Neogenesis and Development in Bioengineered Skin
Boosting HGF signaling could improve the creation of hair follicles in lab-made skin.
research Comparison of Hair Shaft Repairing Efficacy Between Panthenol and Hydrolyzed Protein
Panthenol is more effective than hydrolyzed protein at improving hair roughness and reducing breakage.
research Growth Inhibition and Transient Temperature Measurement of Laser-Irradiated Hair Fibers and Follicles
Laser treatment can inhibit hair growth and different hair colors reach different temperatures when lasered.
research Hair Cosmetic Alterations
The document concludes that individualized treatments for hair issues are effective, certain hair changes can indicate neurocutaneous diseases, specific lotions improve skin health, laser hair removal works but needs more study on long-term effects, men's cosmetics are diverse, peeling is effective but can have side effects, and facial pigmentation is often due to overactive skin cells.
research Formulation and Design of Finasteride Coated Microneedles
Finasteride-coated microneedles effectively deliver the drug with minimal scalp damage and high stability.
research Protective Effect of DA-9401 on Acute Use of Finasteride on Sprague-Dawley Rats
DA-9401 protects against hair loss, improves organ function, and prevents infertility caused by finasteride.
research Faculty Opinions Recommendation of Low-Level Light Therapy for Androgenetic Alopecia: A 24-Week, Randomized, Double-Blind, Sham Device-Controlled Multicenter Trial
Low-level light therapy significantly increased hair density and thickness in people with hair loss, but they didn't notice a difference.
research Faculty Opinions Recommendation of Topical Valproic Acid Increases the Hair Count in Male Patients with Androgenetic Alopecia: A Randomized, Comparative, Clinical Feasibility Study Using Phototrichogram Analysis
Applying valproic acid on the scalp increased hair growth in men with hair loss.
research Pattern of Skin Disease in Hail Region of Saudi Arabia
The most common skin diseases in Hail, Saudi Arabia, are eczema and acne, with more women affected than men.
research Efficacy of Baricitinib in Patients With Various Degrees of Alopecia Areata Severity: Results From Brave-AA1 and Brave-AA2
Baricitinib was effective in regrowing hair in patients with different levels of alopecia areata severity.
research The Efficacy of Spiritual Healing
The document concludes that there is no credible evidence that distant healing works, and it should not be further studied in medical literature.
research Impact on Quality of Life Among Females with Diffuse Hair Loss at a Tertiary Care Centre: A Cross-Sectional Study
Diffuse hair loss significantly worsens quality of life for females, especially younger women and those with long-term hair loss.
research Vitamin D Deficiency Among Depressed Women: A Cross-Sectional Study in Iraq
Most women with depression in the study had low vitamin D levels.
research Pathology in Practice: Sebaceous Gland Dysplasia in Persian Cats
Three related Persian cats have a rare, likely hereditary skin condition causing hair loss and poor coat quality, with limited treatment options.
research Correspondence
RAPK is a rare skin disorder with pigmented spots, mainly on hands and feet, starting in youth.
research Pleural Effusion Induced by Systemic Consumption of Topical Minoxidil: A Rare Case Report
Topical minoxidil can rarely cause pleural effusion if ingested.
research P21Waf1/Cip1 Is Differentially Expressed in Epidermal Versus Follicular Melanocytes and Melanoma Cells and Is Phenotypically Regulated by UVB-Mediated Apoptosis
The protein p21 is more abundant in normal skin cells than in melanoma cells and may help protect against melanoma, with UVB light affecting its levels.
research Reply
The authors defended their methods for measuring hair density and caliber, emphasizing the need for consistent photography and manual counting for accuracy in evaluating hair loss treatments.