January 2018 in “Online Publication Service of Würzburg University (Würzburg University)” This study found that donor age and culture medium significantly impact the quality of human full-thickness skin models, with implications for their use as animal model alternatives in research.
68 citations
,
April 2002 in “Journal of Human Nutrition and Dietetics” This study found that although diabetic patients undergoing a very low calorie diet experienced faster weight loss initially, those on a conventional diet and exercise plan maintained weight loss more effectively over five years.
February 2020 in “Research Square (Research Square)” In this study, skin tags in Irish adults with morbid obesity were associated with higher blood pressure, higher HbA1c levels, and a greater prevalence of diabetes and hypertension, suggesting increased cardiovascular risk.
30 citations
,
September 2013 in “PubMed” This study found that Chinese women with PCOS have a high prevalence of mild to moderate NAFLD, particularly when BMI is ≥24 kg/m(2), emphasizing the role of insulin resistance and metabolic abnormalities.
October 2023 in “Journal of Mind and Medical Sciences” In this study, metabolic surgery led to a weight loss of 10.8 to 12.6 kg and improvement in body composition and HbA1c levels among patients from North-Eastern Romania, with nutritional intervention proving safe over six months.
5 citations
,
May 2019 in “Hormone and Metabolic Research” This study reported that in embryo transfer cycles for women with nonclassic 21-hydroxylase deficiency, dexamethasone use was associated with improved pregnancy rates, and maintaining a BMI below 23.36 kg/m² increased pregnancy probabilities.
December 2024 in “International Journal of Advanced Research” In this study, the authors concluded that metformin and vitamin D are important for managing PCOS by improving insulin resistance and hormonal imbalances, especially in women with a BMI of 25 kg/m² or higher.
In this laboratory study, researchers developed and tested two in vitro models to simulate atopic dermatitis using HaCaT cells, finding that azithromycin displayed epithelial-strengthening properties in one model, potentially offering insights for future research on skin disease interventions.
19 citations
,
January 2017 in “Hormone Molecular Biology and Clinical Investigation” This study found a high prevalence of hyperandrogenemia in women with PCOS, with distinct biochemical differences according to BMI and presence of hyperandrogenemia.
17 citations
,
January 2012 in “IOSR Journal of Environmental Science Toxicology and Food Technology” This study found that high doses of ethyl acetate extract from Tridax procumbens can have specific toxic effects in rats, including organ damage and significant changes in some serum biochemical parameters.
24 citations
,
January 2004 in “The scientific world journal/TheScientificWorldjournal” This study found that HAIR-AN syndrome is prevalent among young women, and a multifaceted treatment approach effectively reduces symptom severity and prevents further consequences.
379 citations
,
May 2016 in “Cochrane library” This review concluded that corticosteroids improve muscle strength and function in boys with Duchenne muscular dystrophy over short-term periods, but evidence on prolonging walking ability remains insufficient, and side effects are common.
45 citations
,
September 2011 in “Journal of the European Academy of Dermatology and Venereology” This study found that obesity is associated with several skin conditions, such as striae and pseudoacanthosis nigricans, which may serve as markers of excessive weight.
December 2024 in “American Journal of Case Reports” This case report highlights that insulin resistance in PCOS can occur even in underweight patients, as demonstrated by a 24-year-old woman who improved her menstrual cycle, acne, and hirsutism with metformin and dexamethasone over 6 months.
September 2019 in “Journal of evolution of medical and dental sciences” In this study of patients with obesity, the most common skin disorders observed were acanthosis nigricans, skin tags, and stretch marks, emphasizing the impact of obesity on dermatological health.
December 2022 in “Journal of Sulaimani Medical College” This study observed that laparoscopic sleeve gastrectomy significantly reduced BMI and helped improve or eliminate certain obesity-related comorbidities over six months, with a low incidence of postoperative complications.
16 citations
,
January 2012 in “Indian Journal of Endocrinology and Metabolism” This case series describes six women with both PCOS and Graves' disease, suggesting a possible shared underlying cause for their co-occurrence.
7 citations
,
June 2024 in “PubMed” This study found that bariatric surgery led to significant weight loss in patients, but it also resulted in complications like nutrient deficiencies, highlighting the need for dietary compliance and professional follow-up.
2 citations
,
October 2019 in “International Journal of Research in Dermatology” This study found that obese patients had higher prevalence and severity of skin conditions like acanthosis nigricans and infections compared to those with normal BMI, which could help detect metabolic syndrome early.
128 citations
,
September 2011 in “British Journal of Dermatology” Obesity is linked to various skin problems and may increase the risk of skin cancer.
116 citations
,
December 2013 in “European journal of endocrinology” This study found that combining liraglutide with metformin led to greater weight loss and waist circumference reduction than either treatment alone in obese women with PCOS resistant to metformin monotherapy.
29 citations
,
September 2023 in “Journal of Clinical Medicine” This study found that semaglutide significantly reduced body weight in almost 80% of obese PCOS patients unresponsive to lifestyle changes, often normalizing menstrual cycles with few side effects.
21 citations
,
July 2016 in “Gynecological Endocrinology” This study found that women with polycystic ovary syndrome have elevated cardiovascular risk markers, with levels being higher in obese participants compared to non-obese participants.
18 citations
,
September 2017 in “Clinics in Dermatology” This review highlights the role of dermatologists in detecting early cutaneous signs of obesity-related metabolic syndrome, which may enable earlier treatment to prevent long-term consequences; it reports no new clinical results.
18 citations
,
January 2015 in “Journal of obesity and weight loss therapy” This study found that an 8-week low-starch/low-dairy diet led to weight loss, improved insulin sensitivity, and reduced testosterone levels in women with PCOS.
8 citations
,
August 2016 in “Annales de Dermatologie et de Vénéréologie” This case report details a rare instance of scurvy linked to anorexia nervosa in a 48-year-old woman, characterized by atypical symptoms and successfully treated with vitamin C supplements.
6 citations
,
February 2014 in “Actas Dermo-Sifiliográficas” This study found that acanthosis nigricans and skin tags in nondiabetic, obese patients were significantly associated with higher insulin levels, suggesting they may serve as clinical markers of hyperinsulinemia.
1 citations
,
March 2024 in “Türk Kadın Sağlığı ve Neonatoloji Dergisi” This study concluded that among patients with polycystic ovary syndrome at their clinic, the most common phenotype was group A, with lifestyle modification and oral contraceptives being frequently used treatments.
1 citations
,
January 2016 in “Journal of gastrointestinal & digestive system” The researchers reported that the SAGI PGP procedure resulted in excess weight loss of over 90% in the first year and normalized blood sugar levels without medication among diabetic patients by the first month post-operation.
1 citations
,
December 2013 in “ThinkTech (Texas Tech University)” This study found that an 8-week low insulinemic diet significantly improved anthropometric, biochemical, and metabolic measures, binge eating behaviors, and quality of life in women with PCOS.