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Hormonal treatments can help with acne, especially in women, by lowering androgen levels or blocking their effects.

Norgestimate is the most effective birth control progestin for reducing an enzyme linked to acne and excessive hair growth in women.

Some common medications can harm male fertility, but many effects can be reversed.

Hormonal treatments can help with acne but are not the first choice due to side effects and the need for careful patient selection.

Certain medications including flutamide, spironolactone, and others effectively reduce excessive hair growth in women, especially when combined with lifestyle changes.

Santolina chamaecyparissus oil effectively fights fungal infections.

Most dermatologic medications are safe during pregnancy and breastfeeding, but some should be avoided due to potential risks.

Hair color loss can indicate the effectiveness of a drug targeting the KIT protein in mice and humans.

S5αR inhibitors might help treat schizophrenia and other mental disorders but need more research.

Janus kinase inhibitors are promising drugs for treating autoimmune and inflammatory diseases.

The document explains how the male reproductive system works, its role in making testosterone, and how conditions like obesity can disrupt it, leading to low testosterone and fertility issues.

Finasteride slowly binds to 5-alpha-reductase, affecting enzyme stability and inhibitor potency.

Low-dose finasteride may cause lasting sexual dysfunction and suicidal thoughts in young men.

People with diabetes or obesity should manage their conditions carefully as they have a higher risk of severe COVID-19.

European guidelines recommend regular eye and ear exams, skin care, vitamin D supplements, and cautious use of medications for managing congenital ichthyoses.

The conclusion is that the best initial treatment for hirsutism is usually oral contraceptives, with the addition of antiandrogens or insulin sensitizers if needed, and topical eflornithine or laser treatments as supplementary options.

Human hair follicles can make and process prostaglandins, which may affect hair growth.

The transscrotal testosterone patch normalizes hormone levels in men with AIDS and weight loss but does not improve weight, body mass, or quality of life.

Vitiligo causes white skin patches and is linked to autoimmune issues.

Some birth control pills have a higher risk of blood clots than others.

Finasteride almost fully depletes allopregnanolone in rat brains and enhances 20α-DHP, but doesn't change 3α-DHP levels.

Cats with atopic dermatitis often have severe, year-round itching and respond well to certain treatments.

Fadrozole and finasteride change gene expression related to sex hormones and thyroid hormones in frog larvae development.

Lower levels of certain brain chemicals are linked to worse PTSD symptoms in men.

The document concludes that targeting 5α-reductase, the androgen receptor, and hair growth genes, along with using compounds with anti-androgenic properties, could lead to more effective hair loss treatments.

Minoxidil helps hair growth and reduces shedding in women.

Dihydrotestosterone increases the activity of an enzyme in pubic skin cells that converts testosterone to dihydrotestosterone.

All three treatments reduce hirsutism, but spironolactone works best long-term.

Different factors affect where drugs are absorbed in the small intestine, which is important for effective medication use.

Antiandrogens, particularly flutamide and CPA, are most effective for treating hirsutism, with long-term use needed for best results.