45 citations,
May 2012 in “The Journal of Steroid Biochemistry and Molecular Biology” Too much AKR1C3 enzyme causes resistance to finasteride by increasing testosterone.
89 citations,
May 1999 in “Allergy” The yeast Pityrosporum ovale can cause skin allergies and infections, and antifungal treatments like ketoconazole are effective against it.
9 citations,
January 2008 in “Medical mycology” A dog's skin infection caused by the fungus Chaetomium globosum was effectively treated with ketoconazole.
2 citations,
January 1983 in “Archives of Dermatology” A 3-year-old boy's scalp infection was treated with ketoconazole.
2 citations,
December 2017 in “PubMed” A long-term pubic rash was finally diagnosed as white piedra and cured with ketoconazole.
1 citations,
January 2022 in “Advances in animal and veterinary sciences” Ketoconazole cream effectively treats fungal skin infections in cats.
1 citations,
September 2016 in “Veterinary dermatology” A combination of ciclosporin and ketoconazole can effectively treat severe hair loss in dogs.
1 citations,
February 2014 in “Revista de investigaciones veterinarias del Perú” A pet rabbit had a skin infection that was cured with ketoconazole.
15 citations,
January 2009 in “Indian journal of dermatology, venereology, and leprology” Scalp white piedra can be treated with oral itraconazole and topical ketoconazole.
121 citations,
January 1991 in “Acta dermato-venereologica” Terbinafine quickly builds up in skin and hair, staying effective for over 3 weeks.
90 citations,
May 2019 in “Drugs” Long-term use of azole antifungals can cause hair loss, hormonal imbalances, and severe skin reactions.
78 citations,
October 2003 in “Cochrane library” Cyproterone acetate with estradiol may subjectively improve excessive hair growth in women, but it's not clinically better than other treatments.
59 citations,
February 2003 in “Veterinary Dermatology” Cyclosporin is effective for treating skin conditions in small animals, but requires careful dosing and monitoring for side effects.
55 citations,
July 2013 in “Dermatologic therapy” Some dermatological medications can impair male fertility, so consult a doctor before trying to conceive.
36 citations,
June 2012 in “PubMed” There are potential treatments for pattern baldness, but more research is needed to confirm their effectiveness.
35 citations,
November 1996 in “Journal of the American Academy of Dermatology” Itraconazole was effective in treating unusual M. canis infections in only one of two HIV-infected men.
33 citations,
June 2007 in “International Journal of Pharmaceutics” The conclusion is that measuring how drugs partition into artificial sebum is important for predicting their delivery into hair and sebaceous follicles, and it provides better information than traditional methods.
32 citations,
November 1996 in “International Journal of Dermatology” Antiandrogens can help treat skin conditions like acne and excessive hair in women when used carefully.
24 citations,
March 1998 in “Mycoses” Early diagnosis and effective treatment of kerion Celsi prevent scarring and permanent hair loss.
20 citations,
February 2016 in “American Journal of Pathology” The genes OVOL1 and OVOL2 are important for hair growth and may be involved in a type of skin tumor.
18 citations,
November 1989 in “Clinical and experimental dermatology” Griseofulvin is the best treatment for severe scalp infection caused by Microsporum canis.
14 citations,
September 2015 in “Expert Opinion on Therapeutic Targets” The conclusion is that while oral contraceptive pills are effective for PCOS-related high androgen levels, new treatments with fewer side effects are needed.
12 citations,
August 2016 in “Mycopathologia” A man's pubic hair infection was treated by shaving and using antifungal medications.
11 citations,
January 1998 in “Dermatology” Spironolactone works well for acne and hirsutism, isotretinoin is very effective for acne and may have antiandrogenic effects, and 5 alpha-reductase inhibitors should be considered antiandrogens.
9 citations,
April 1993 in “Journal of the National Cancer Institute” Interleukin-2 treatment improved hair growth, sexual function, and reduced fungal infection in a patient with thymoma-related symptoms.
9 citations,
April 1987 in “International Journal of Dermatology” Stopping the depression medication improved the woman's eyebrow hair loss, and a treatment for a skin condition caused by mites was effective.
8 citations,
October 1989 in “International Journal of Dermatology” Cytochrome P-450 enzymes in the skin help break down various substances and could be targeted to treat skin conditions.
7 citations,
September 2013 in “Current Dermatology Reports” Some skin medications are safe for pregnant women, but others pose risks or should not be used.
6 citations,
August 2009 in “Mini-reviews in Medicinal Chemistry” Different drugs can treat high male hormone levels in women, but they have various effects and some may harm a fetus.
6 citations,
October 1998 in “PubMed” Antifungal treatment can improve severe skin infections with cutaneous horns.