140 citations
,
August 2011 in “Biomaterials” This study observed that keratose, derived from human hair, integrated well in mouse tissue and remodeled with collagen, suggesting potential as a non-toxic biomaterial for regenerative applications.
54 citations
,
January 1983 in “Archives of Dermatology” This article presents two cases of keratosis follicularis spinulosa decalvans and reviews its features, highlighting characteristic progression from keratosis pilaris in infancy to cicatricial alopecia in childhood.
1 citations
,
January 2019 in “Pan African Medical Journal” This case report describes a 30-year-old woman with keratosis pilaris treated with emollients and keratolytics, resulting in slight improvement.
September 1978 in “PubMed” This study found that chondroitin sulfate levels were higher than hyaluronic acid in skin and hair follicle samples, with the highest concentration observed in prekeratin of hair follicles and wool fibers.
April 1906 in “The American Journal of the Medical Sciences” Keratosis Pilaris Atrophicans causes skin scarring and might be treated with a new synthetic retinoid.
78 citations
,
April 1994 in “Archives of dermatology” This study suggests genetic and clinical heterogeneity in keratosis pilaris atrophicans, with variations in inheritance patterns, severity, and response to treatment among 21 individuals observed.
41 citations
,
January 1992 in “Journal of medical genetics” This study described seven male patients and six female carriers of keratosis follicularis spinulosa decalvans, highlighting distinct dermatological and ophthalmic markers including follicular hyperkeratosis and corneal dystrophy.
37 citations
,
September 2005 in “Australasian Journal of Dermatology” This case report describes a 27-year-old man with a unique association of keratosis follicularis spinulosa decalvans and acne keloidalis nuchae, successfully treated with oral isotretinoin.
35 citations
,
January 2008 in “American Journal of Clinical Dermatology” This case report further supports the association of keratosis follicularis spinulosa decalvans with acne keloidalis nuchae and tufted hair folliculitis.
32 citations
,
February 2008 in “Journal of the American Academy of Dermatology” This case report describes a family with autosomal dominant transmission of keratosis follicularis spinulosa decalvans, with observed treatment refractoriness in multiple topical and systemic therapies.
23 citations
,
February 2015 in “The American journal of pathology” This study found that the absence of sebaceous glands may be an early factor in the development of keratosis pilaris, leading to hair shaft and skin barrier abnormalities, independent of filaggrin mutations.
20 citations
,
November 2014 in “JAMA dermatology” This study found that three treatments with the 810-nm diode laser improved skin texture and roughness/bumpiness in keratosis pilaris patients, although it did not reduce redness.
19 citations
,
April 2016 in “Case Reports in Dermatology” This case report highlights an instance of nilotinib-induced keratosis pilaris without alopecia or pruritus, emphasizing the need for awareness to optimize patient outcomes.
18 citations
,
March 1992 in “Archives of Dermatology” This case report presents a 28-year-old man with scarring alopecia unresponsive to topical treatments, alongside a family history of keratosis pilaris and unique curly scalp hair.
17 citations
,
January 2011 in “Indian journal of dermatology, venereology, and leprology” This paper describes a rare case of keratosis follicularis spinulosa decalvans in a nine-year-old girl, a condition typically more severe in males due to its X-linked inheritance.
15 citations
,
May 2014 in “Journal of dermatology” This review suggests the existence of a new syndrome characterized by keratosis pilaris, ulerythema ophryogenes, and monosomy 18p, emphasizing its potential utility in diagnosing monosomy 18p.
10 citations
,
August 2016 in “Dermatology Online Journal” This article describes cutaneous reactions including keratosis pilaris-like eruptions in a patient on nilotinib for chronic myelogenous leukemia, emphasizing the importance of accurately classifying such eruptions.
9 citations
,
July 2022 in “Dermatology and Therapy” In this study, long-pulsed 755-nm alexandrite laser treatment for keratosis pilaris significantly improved skin roughness and redness, as well as follicular plug reduction, with good safety and patient satisfaction compared to a moisturizing lotion alone.
6 citations
,
July 2021 in “Frontiers in Genetics” This study identified a new heterozygous missense variant in CST6 associated with autosomal dominant keratosis follicularis spinulosa decalvans in an Austrian family, affecting epidermal differentiation and hair formation.
6 citations
,
July 2011 in “Journal of Plastic Reconstructive and Aesthetic Surgery” This case report describes a successful eyebrow reconstruction using hair follicle micrografts in a patient with dormant keratosis pilaris atrophicans, demonstrating potential for this technique in similar conditions.
5 citations
,
January 2021 in “Indian Journal of Pharmacology” This case study reports generalized keratosis pilaris as a rare cutaneous side effect of nilotinib in a 40-year-old woman with chronic myeloid leukemia, highlighting the need for awareness among physicians.
5 citations
,
March 2005 in “Pediatric dermatology” Keratosis Follicularis Spinulosa Decalvans is a rare genetic disorder causing skin and hair issues, often inherited through the X chromosome.
5 citations
,
March 1943 in “Archives of Dermatology and Syphilology” This report describes a rare case of a woman with keratosis follicularis presenting with extensive alopecia and nail abnormalities, adding to the medical literature due to its unusual presentation.
4 citations
,
August 2024 in “Journal of Cosmetic Dermatology” This study reports that injecting a non-cross-linked hyaluronic acid compound into keratosis pilaris-affected skin led to significant improvements in roughness, redness, and overall skin condition, while maintaining a favorable safety profile, making it a promising alternative treatment option.
4 citations
,
September 2015 in “JAAD case reports” This article reviews the characteristics and inheritance patterns of keratosis follicularis spinulosa decalvans, but it does not present new clinical findings, noting the disease's complex and poorly understood pathogenesis.
4 citations
,
September 2010 in “Journal of Dermatological Science” This article reviews keratosis follicularis squamosa, a keratinizing disorder predominantly found in the Japanese population, but reports no new clinical results.
3 citations
,
September 2021 in “Experimental and Therapeutic Medicine” This study described the clinical characteristics of keratosis pilaris atrophicans faciei in 14 patients, noting that earlier diagnosis may enable more targeted treatment options.
3 citations
,
April 2011 in “Journal of the American Academy of Dermatology” This article describes a unique case of unilateral keratosis pilaris atrophicans faciei in a 19-year-old man, noting its clinical similarity to follicular mucinosis, but presents no new general findings.
1 citations
,
March 2023 in “Tidsskrift for Den norske lægeforening” This article provides an overview of keratosis pilaris, discussing its different variants, possible pathogenesis, and treatment options, without reporting new clinical results.
1 citations
,
October 2019 in “European Journal of Dermatology” There are no new clinical results reported in this discussion of pityriasis rubra pilaris diagnosis and treatment, which notes frequent treatment failures and highlights reliance on clinical and histopathological findings.