research Deletion of Hypoxia-Inducible Factor Prolyl 4-Hydroxylase 2 in FoxD1-Lineage Mesenchymal Cells Leads to Congenital Truncal Alopecia
Removing HIF-P4H-2 from certain skin cells in mice causes hair loss on the body but not the head.
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90-120 / 1000+ resultsresearch Lipid Signaling in Keratinocytes: Lipin-1 Plays a Part
Lipin-1 is important for skin cell differentiation and skin barrier function.
research Insights Into Structural and Proteomic Alterations Related to pH-Induced Changes and Protein Deamidation in Hair
Haircare products with a pH between 5 and 7 are best for maintaining healthy hair.
research The Development of an In Vitro Human Hair Follicle Organoid With a Complexity Similar to That In Vivo
Scientists created a lab-grown hair follicle model that behaves like real hair and could improve hair loss treatment research.
research AP-2α/AP-2β Transcription Factors Are Key Regulators of Epidermal Homeostasis
AP-2α and AP-2β proteins are essential for healthy adult skin and hair.
research George Ernest Rogers 1927–2021
George Ernest Rogers was a notable scientist who made important discoveries about hair and wool proteins.
research Deletion of Hoxc13 in Frogs Reveals Key Steps in the Molecular Evolution of Cornified Skin Appendages
Deleting the Hoxc13 gene in frogs shows its crucial role in developing skin structures similar to hair.
research Deletion of Hypoxia-Inducible Factor Prolyl 4-Hydroxylase 2 in FoxD1-Lineage Mesenchymal Cells Leads to Congenital Truncal Alopecia
Removing a specific gene in certain skin cells causes hair loss on the body by disrupting normal hair development.
research Why Pashmina Goat Produces Long Hair-Fiber and Barbari Doesn’t: A Differential Gene Expression Study
Pashmina goats produce long hair-fiber due to specific gene expressions related to hair growth.
research An Integrated Model of Alopecia Areata Biomarkers Highlights Both Th1/Th2 Upregulation, with Stronger Correlations Between Th2 Activation and Disease Severity
Both Th1 and Th2 immune responses are increased in alopecia areata, with Th2 response more strongly linked to how severe the disease is.
research Generation of iPS-Derived Model Cells for the Analysis of Hair Development
Researchers created a cell model to study hair growth and test hair-growth drugs.
research Hair Physiology and Grooming
Hair is complex, varies in type, and plays a big role in attractiveness and culture.
research The Formulation and In-Vitro Evaluation of WS Biotin, a Novel Encapsulated Form of D-Biotin with Improved Water Solubility for Hair and Skin Treatment Applications
WS Biotin, a new form of D-Biotin, improves water solubility and shows potential for hair and skin care without being toxic at low levels.
research Painful Thickened Skin on the Soles of the Feet
The man has a genetic skin condition called pachyonychia congenita.
research Electron Microscope Studies of Hair and Wool
Hair and wool have complex microscopic structures with microfibrils and varying cystine content.
research Generation of Folliculogenic Human Epithelial Stem Cells from Induced Pluripotent Stem Cells
Scientists created stem cells that can grow hair and skin.
research Biology and Genetics of Hair
The document concludes that understanding the genes and pathways involved in hair growth is crucial for developing treatments for hair diseases.
research FOXN1 Is Critical for Onycholemmal Terminal Differentiation in Nude (Foxn1nu) Mice
The Foxn1 gene is essential for normal nail and hair development.
research Endocrine Controls of Keratin Expression
Hormones control keratin production in skin and hair.
research Frontal Fibrosing Alopecia Shows Robust T Helper 1 and Janus Kinase 3 Skewing
Frontal fibrosing alopecia is linked to increased immune system activity and reduced stem cells, suggesting early treatment targeting this pathway might prevent hair follicle damage.
research Mutations In AEC Syndrome Skin Reveal A Role For p63 In Basement Membrane Adhesion, Skin Barrier Integrity And Hair Follicle Biology
Mutations in the p63 gene affect skin adhesion, barrier integrity, and hair growth.
research Gsdma3 Is Required for Hair Follicle Differentiation in Mice
The Gsdma3 gene is essential for normal hair development in mice.
research Hair Keratin Pattern in Human Hair Follicles Grown In Vitro
Human hair follicles grown in vitro maintain normal keratin patterns and structure.
research Unraveling the Molecular Mechanisms of Hair and Nail Genodermatoses
Genetic discoveries are key for understanding, diagnosing, and treating inherited hair and nail disorders.
research Scalp Biomarkers During Dupilumab Treatment Support Th2 Pathway Pathogenicity in Alopecia Areata
Dupilumab treatment reduces Th2-related markers and helps hair growth in alopecia areata, showing Th2's role in the condition.
research The Hair Shaft: Normality, Abnormality, and Genetics
Hair microscopy is useful for diagnosing hair disorders, but clear definitions are needed for accurate genetic analysis.
research The Human Type II Keratin Gene Cluster on Chromosome 12q13.13: Final Count or Hidden Secrets?
The document concludes that the human keratin gene cluster is complex, with a need for updated naming to reflect over 50 functional genes important for hair and skin biology.
research Strategies for Improved Hair Binding: Keratin Fractions and the Impact of Cationic Substructures
Certain treatments can increase protein binding to natural hair but are less effective on permed hair.
research Early Dengue Virus Infection in Human Skin: A Cycle of Inflammation and Infectivity
Chicken feather gene mutation helps understand human hair disorders.
research Monilethrix
A 12-year-old girl was diagnosed with monilethrix, a genetic condition causing fragile, beaded hair that breaks easily, with no effective treatment available.