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Activating the Sonic hedgehog pathway can help regenerate hair follicles during wound healing in mice, potentially improving regeneration after injury.

Combining platelet-rich plasma injections and gel may effectively treat morphea, improving skin elasticity and reducing pain.

EGFR helps control how hair grows and forms without needing p53 protein.

BMAL1 controls skin cell growth and UV damage risk, peaking at night.

RXRα is crucial for proper immune response and links diet to immune function.

A new therapy for a skin blistering condition has not been developed yet.

Faulty Notch signalling may cause hair follicle changes and inflammation in hidradenitis suppurativa.

Genetic changes in mice help understand skin and hair disorders, aiding treatment development for acne and hair loss.

Skin stem cells interacting with their environment is crucial for maintaining and regenerating skin and hair, and understanding this can help develop new treatments for skin and hair disorders.

PTEN helps control the number and health of skin stem cells by working with the protein BMAL1.

The circadian clock plays a key role in hair growth and its disruption can affect hair regeneration.

Deleting the CD271 gene in mouse skin cells leads to disorganized skin and increased hair growth, suggesting CD271 is important for skin health.

Deleting the PTEN gene in mice causes nerve cells to grow larger and heal better after injury, but may cause overgrowth and hair loss in older mice.

Pangolins have lost some skin-related genes, but kept others, leading to their unique scales and skin features.

Vitamin D and calcium are essential for normal hair growth.

miR-31 regulates hair growth by controlling gene expression in hair follicles.

Hair follicles could be used to noninvasively monitor our body's internal clock and help identify risks for related diseases.

The document concludes that the skin's immune system is complex, involving interactions with hair follicles, nerves, and microbes, and can protect or cause disease, offering targets for new treatments.

GRK2 is essential for healthy hair follicle function, and its absence can lead to hair loss and cysts.

ATP-dependent chromatin remodeling is crucial for skin development and stem cell function.

A specific enzyme is essential for proper hair follicle stem cell development and healthy skin.

Rac1 is essential for proper hair structure and color.

Loss of a specific protein in skin cells causes symptoms similar to psoriasis.

Involucrin gene expression is controlled by specific proteins and signaling pathways.

Skin bacteria, specifically Staphylococcus aureus, help in wound healing and hair growth by using IL-1β signaling. Using antibiotics on skin wounds can slow down this natural healing process.

MicroRNAs are important for skin health and could be targets for new skin disorder treatments.

The review found that different stem cell types in the skin are crucial for repair and could help treat skin diseases and cancer.

The HIF-2α/ARNT complex is important for hair follicle development by controlling cell growth.

Apoptosis is essential for human skin development and forming a functional epidermis.

MED1 is essential for normal hair growth and maintaining hair follicle stem cells.