research Investigation of the Molecular Identity of the Junctional Zone in Human Skin
GATA6 is important for maintaining and differentiating cells in a key area of human skin.
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research Single Cell Transcriptome Profiling of Human Interfollicular Epidermis Reveals Robust Heterogeneity and Divergent Differentiation Lineages
The human skin's outer layer has more variety in cell types and development paths than previously thought.
research Non-Coding Double-Stranded RNA Induces Retinoic Acid Synthesis and Retinoid Signaling to Control Regeneration
Double-stranded RNA helps regenerate hair follicles by increasing retinoic acid production and signaling.
research SnapshotDx Quiz: February 2018
Blocking certain pathways with kinase inhibitors may help treat cutaneous lupus erythematosus.
research Integration of Biochemical and Mechanical Signals at the Nuclear Periphery: Impacts on Skin Development and Disease
The conclusion is that the nuclear lamina and LINC complex in skin cells respond to mechanical signals, affecting gene expression and cell differentiation, which is important for skin health and can impact skin diseases.
research Building a Functional Niche for Hair Follicle Stem Cells
Deleting the CRIF1 gene in mice disrupts skin and hair formation, certain proteins affect hair growth, a new compound may improve skin and hair health, blood cell-derived stem cells can create skin-like structures, and hair follicle stem cells come from embryonic cells needing specific signals for development.
research Fisetin Promotes Differentiation, Inhibits Proliferative and Inflammatory Responses in Cultured Human Cells and Alleviates Psoriasiform Dermatitis in Mice
Fisetin may help treat psoriasis and reduce skin inflammation.
research Hair-Follicle-Associated Pluripotent Stem Cells
HAP stem cells can repair nerves and spinal cords by becoming Schwann cells.
research The Relevance of Collagen XVII Expression in Epidermal Differentiation and Proliferation
Collagen XVII is crucial for skin cell growth and nail health.
research Analysis on the Maintenance Mechanisms of Human Interfollicular Epidermal Stem Cells and Their Niche
Epidermal stem cells use integrin β1 and α6 as markers and CD271+ cells help maintain skin health and heal wounds.
research In Vitro Mesenchymal–Epithelial Interaction Facilitates De Novo Hair Follicle Formation
Adult skin cells can be used to create new hair in a lab.
research Signaling Networks Between Stem Cell Precursors, Transit Amplifying Progenitors, and Their Niche in Developing Hair Follicles
Blocking Prostaglandin D₂ (PGD₂) could help treat hair loss.
research Redox-Directed Interventions Targeting Skin Photodamage
Some treatments can improve skin's defense against damage, but overuse may cause other skin problems.
research Proteomics Characterization of Primary Human Oral Epithelial Cells Using a Novel Culture Technique for Tissue Regeneration
ePUKs could be valuable for regenerative medicine due to their wound healing abilities.
research Increasing Mupirocin Resistance in Pediatric Methicillin-Resistant Staphylococcus Aureus Skin and Soft-Tissue Infections in New York: A Genomic Approach
There's a growing resistance to the antibiotic mupirocin in children's skin infections caused by MRSA in New York.
research Nociceptive and Non-Nociceptive Roles of TRPV3 and Its Druggability
TRPV3 could be a target for treating pain, skin disorders, and hair problems, but more research is needed to create effective drugs.
research Vitamin D and the Epidermis
Vitamin D is important for skin cell growth and health, and its active form and receptor play key roles in skin and hair processes.
research Research Snippets: Dermatological Genetics and Conditions
New gene mutations linked to skin conditions were found, bacteria and chemicals may worsen acne, a dog mutation could exist in humans, virus-like elements might be involved in psoriasis, and a vitamin D3 treatment doesn't prevent chemotherapy-related hair loss.
research The Effects of Extracellular Matrix and Growth Factors on Dermal Papilla Cell Proliferation
Different substances affect hair and skin cell growth in various ways.
research TLR9 Activation in Large Wound Induces Tissue Repair and Hair Follicle Regeneration via Gamma Delta T Cells
Activating TLR9 helps heal large wounds and regrow hair by involving a specific type of immune cell.
research The Impact of Prolactin and Vitamin D Levels as Prognostic Markers of Female Hair Loss
High prolactin and low vitamin D levels may be linked to hair loss in women.
research A Case Report of Sebaceous Filaments
Topical tretinoin effectively treated sebaceous filaments, improving skin appearance.
research Mesenchymal Stem Cells Paracrine Proteins From Three-Dimensional Dynamic Culture System Promoted Wound Healing in Third-Degree Burn Models
Mesenchymal stem cell proteins in a special gel improved healing of severe burns.
research Pathogenetically Significant Risk Factors for Development of Androgenetic Alopecia
Inflammation in hair follicles is a key risk factor for developing common baldness.
research Interferon-24 Regulates the Expression of MMP1 and Dermal Collagen of the Skin
IL-24 contributes to skin aging by increasing collagen-degrading enzymes and decreasing collagen production when exposed to air pollution.
research Novel Human 3D Skin Model for Skin Aging Research
Scientists created a 3D skin model that shows typical signs of aging, which can help in aging research.
research Local Injection With Anti-Herpes Simplex Virus Antibodies Protects Against Development of Herpes Simplex Virus-Induced Sweating Disturbance
Injecting anti-herpes antibodies locally can prevent skin lesions and sweating problems caused by herpes simplex virus in mice.
research Amelioration of Symptoms of Dry and Eczema-Prone Skin by an Oil-in-Water Emulsion Containing a Combination of Zingiber Officinale Root Extract and CBD with Antioxidative and Anti-Inflammatory Activity In Vitro
An oil-in-water emulsion with CBD and ginger root extract significantly improved symptoms of dry and eczema-prone skin.
research Modulation of YBX1 Phosphorylation Determines Epidermal Stem Cell Function
Changing YBX1 protein activity affects skin stem cell function and aging.
research Autophagy Controls the Protein Composition of Hair Shafts
Autophagy is important for determining the protein makeup of hair.