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This study found that hair follicle stem cells can proliferate and differentiate into keratinocytes on chitosan skin-engineered templates, suggesting potential applications in regenerative medicine.

This study suggests that human induced pluripotent stem cells can be used to generate dermal papilla equivalent cells, potentially aiding hair follicle regeneration and drug discovery for hair diseases.

This study found that inserting isolated hair follicle units into engineered dermis promoted differentiation and maturation of tissue-engineered skin, maintaining hair follicle morphology and generating skin appendages like sebaceous glands.

This study found that skin bacteria promote regeneration in wound-induced hair follicle neogenesis, suggesting a role for IL-1β signaling and challenging the belief that infection inhibits healing.

In this study, the Foxn1(-/-) nude phenotype was associated with an altered regulation of epithelial progeny in skin, offering a valuable model for investigating stem cell niche maintenance and regulation.

In this study, researchers used transcriptomics and modeling to uncover previously unknown cell populations and marker genes in developing hair follicles, providing insights into early cell fate establishment and offering tools for further research on skin appendages.

This review provides a comprehensive guide to serum-free human hair follicle organ culture methods, highlighting research opportunities, standardization efforts, and potential applications without reporting new empirical findings.

This study suggests a regulatory model where HOXC13 activates Foxn1, affecting hair and nail differentiation, supported by similarities in Hoxc13(tm1Mrc) and Foxn1(nu) mice phenotypes and gene expression patterns.

This study developed an in vitro system to analyze human skin progenitor cells' ability to form hair peg-like structures, providing insights for engineering hair follicle organoids.

This review discusses the identification and roles of different epidermal stem cell types in skin homeostasis and repair, and reports no new experimental findings.

This study found that high-dose radiation can induce accelerated cellular senescence, inflammation, and loss of epithelial stem cells in mouse and human skin, contributing to radiation dermatitis.

This study found that KY19382, a small molecule activating the Wnt/β-catenin pathway, significantly improved wound healing by enhancing cell migration, increasing collagen and stem cell markers, and accelerating re-epithelialization and neo-epidermis formation in a murine model without causing significant cytotoxicity.

This study found that sulfur mustard affects hair follicles and sebaceous glands in the skin by causing cellular damage, inflammation, and disrupting wound healing processes in hairless mice.

This study describes a protocol for generating hair follicle germ-like organoids from human skin cells, which may aid in alopecia drug discovery and understanding hair follicle regeneration.

In this study, researchers used a 3D printing technique to spatially pattern human dermal papilla cell spheroids in a collagen matrix, enhancing skin and hair regeneration in a mouse model, with notable upregulation of key genes for hair follicle formation compared to traditional cell cultures.

This study found that the synthetic retinoid EC23 effectively induces keratinocyte hyperproliferation and enhances hair growth in mice, showing more potency than all-trans retinoic acid.

This research found that the microtubule catastrophe factor KIF18B plays a crucial role in promoting spindle orientation in keratinocytes, linking this process to cell fate decisions during hair follicle morphogenesis.

This study identified a unique transcriptional signature in occipital hair follicles that may protect them from miniaturization in androgenetic alopecia, using an animal-free model to investigate gene roles.

This study suggests that epidermal turnover could be a regulated mechanism of iron excretion, with systemic iron levels influencing keratinocyte behavior and differentiation markers in the skin.

This study found that tight junctions extend to the most superficial layer of the stratum granulosum in human skin, challenging previous claims of their limited presence in the epidermis.

In this study, the immunohistochemical and lectin binding profiles of basal cell carcinoma closely resembled those of the outer root sheath of vellus hair follicles, suggesting a potential histochemical relationship.

This study found that orally administered hydrolyzed keratin peptide promoted hair growth and enhanced cellular proliferation and antioxidant capacity in mice and human cell models, suggesting its potential as a functional food ingredient for hair health.

This study explored hair follicle research by co-culturing dermal papilla cells, keratinocytes, and endothelial cells in spheroids, finding elevated hair growth factor expression and potential for creating skin equivalents with hair through a "hair-on-a-chip" approach.

This study found that hyaluronic acid increased the size of hair follicle germ-like aggregates and the number of proliferative cells but did not maintain specific markers during the process.

This study found that ectodermal precursor cells derived from human induced pluripotent stem cells may enhance hair follicle morphogenesis through improved epithelial-mesenchymal interactions when cocultured with dermal cells.

This study found that deleting the transcription factor Twist1 in keratinocytes significantly reduced UVB-induced skin carcinogenesis in mice, suggesting a potential target for preventing cutaneous squamous cell carcinoma.

In laboratory experiments, this study found that the topical prodrug SCD-153, a derivative of 4-methyl itaconate, reduced inflammation-related gene expression and induced significant hair growth in mice, suggesting it as a promising treatment candidate for alopecia areata.

This study found that 4-aminopyridine significantly enhanced skin wound healing by accelerating wound closure, improving skin architecture, and promoting hair follicle neogenesis and tissue regeneration.

Krox20 is crucial for hair growth and maintaining skin stem cells.

This study found that deleting the Twist1 gene in skin keratinocytes significantly reduced UVB-induced skin cancer and hyperproliferation in mice and suggested Twist1 as a target for skin cancer prevention.