5 citations,
July 2022 in “Orphanet journal of rare diseases” RSPO1 mutations in certain patients lead to skin cells that don't develop properly and are more likely to become invasive, increasing the risk of skin cancer.
92 citations,
April 1999 in “The journal of investigative dermatology/Journal of investigative dermatology” Nonpalmoplantar skin cells can be made to express keratin 9 by interacting with palmoplantar fibroblasts.
January 2015 in “American journal of medical and biological research” 11 citations,
January 2010 in “Springer eBooks” 1 citations,
January 2022 in “Springer eBooks” 84 citations,
February 2015 in “Experimental Dermatology” PPARγ is crucial for skin health but can have both beneficial and harmful effects.
11 citations,
May 2016 in “Naunyn-Schmiedeberg's Archives of Pharmacology” A substance called 15-deoxy prostaglandin J2 can cause hair follicle cells to die, which might explain how prostaglandin D2 can lead to hair loss.
42 citations,
June 2019 in “Aging” 3,4,5-tri-O-caffeoylquinic acid promotes hair growth by activating the β-catenin pathway.
78 citations,
June 2003 in “Journal of Investigative Dermatology Symposium Proceedings” TGF-β1 from dermal papilla cells suppresses hair growth, and targeting it may help treat androgenetic alopecia.
7 citations,
December 2020 in “Pharmaceutics” A mix of tocopherol acetate and L-menthol helps grow hair better than using them separately or using minoxidil.
88 citations,
January 2019 in “Journal of Tissue Engineering and Regenerative Medicine” Conditioned media from mesenchymal stem cell cultures could be a more effective alternative for regenerative therapies, but more research is needed.
The research identified key molecules that help hair matrix and dermal papilla cells communicate and influence hair growth in cashmere goats.
11 citations,
August 1997 in “Expert Opinion on Therapeutic Patents” Many potential alopecia treatments need more testing to confirm they promote acceptable hair growth with minimal side effects.
42 citations,
February 2014 in “Stem Cells and Development” Vitamin C helps adipose-derived stem cells grow and may support hair growth.
7 citations,
February 2023 in “Inflammation and Regeneration” The protein interleukin-1 alpha helps regenerate hair follicles and increase stem cell growth in mice.
8 citations,
April 2020 in “Journal of Ethnopharmacology” Herbs might help with hair loss, but more research is needed to confirm their safety and effectiveness.
39 citations,
March 2009 in “Archives of Dermatological Research” Apigenin may help promote hair growth and could treat hair loss.
271 citations,
March 1999 in “Developmental biology” The research shows that a gene called Wnt3 affects hair growth and structure, causing short hair and balding when overactive.
190 citations,
October 2002 in “The FASEB journal” Androgens may cause hair loss by increasing TGF-beta1 from scalp cells, which inhibits hair cell growth.
82 citations,
September 2018 in “Nature Communications” A certain smell receptor in hair follicles can affect hair growth when activated by a synthetic sandalwood scent.
70 citations,
April 2017 in “Lasers in surgery and medicine” Blue light promotes hair growth by interacting with specific receptors in hair follicles.
44 citations,
December 1991 in “Annals of the New York Academy of Sciences” EGF and FGF help hair growth by affecting cell differentiation and fiber growth.
42 citations,
March 2018 in “PLOS Biology” Autophagy is important for human hair growth and health.
14 citations,
July 2021 in “Biomolecules” Centipeda minima extract helps hair grow by activating important growth signals and could be a promising hair loss treatment.
8 citations,
July 2017 in “Biochemical and biophysical research communications” A new compound, BOI, can help hair grow by changing hair cycle phases and increasing certain cell contents.
13 citations,
January 2015 in “Evidence-based Complementary and Alternative Medicine” Garlic chive extract helped mice grow more hair by increasing a specific growth factor.
7 citations,
June 2015 in “European Journal of Plastic Surgery” PRGF treatment safely and effectively helps hair loss.
38 citations,
April 2016 in “Experimental Dermatology” The document concludes that understanding hair follicle cell cycles is crucial for hair growth and alopecia research, and recommends specific techniques and future research directions.
10 citations,
May 2019 in “BMC Complementary and Alternative Medicine” The extract from Bacillus/Trapa japonica fruit helps increase hair growth and could be a potential treatment for hair loss.
42 citations,
March 2008 in “Molecular and Cellular Endocrinology” Hormones and neuroendocrine factors control hair growth and color, and more research could lead to new hair treatment options.