15 citations,
May 2020 in “Journal of Dermatological Treatment” PRP treatment increases hair density and thickness in androgenetic alopecia by 79%.
1 citations,
January 2021 CD4+ skin cells may be precursors to basal cell carcinoma.
16 citations,
November 2022 in “eLife” Both gene and non-gene areas of DNA evolved to make some mammals hairless.
March 2023 in “International Journal of Advanced Research in Science, Communication and Technology” Various medicinal plants like Polygonum multiflorum, Red ginseng extract, and Zizyphus jujuba can potentially treat hair loss, offering benefits like low cost and multiple ways of working. Other effective natural substances include Pygeum africanum, Seneroa, Urtica dioica, and more.
384 citations,
June 2005 in “Genes & development” β-catenin is essential for stem cell activation and proliferation in hair follicles.
3 citations,
September 2023 in “Skin research and technology” New treatments for skin damage from UV light using stem cells and their secretions show promise for skin repair without major risks.
Hairlessness in mammals is due to complex genetic changes in both genes and regulatory regions.
23 citations,
January 2014 in “Molecular Therapy” Applying a special DNA plasmid to the skin can make it thicker and stronger.
11 citations,
October 2018 in “Nucleic Acid Therapeutics” Modified KGF mRNA helps skin cells grow and move faster, which may improve wound healing.
Ajwain seed extract improved skin healing and hair growth in a mouse skin irritation model.
66 citations,
April 1995 in “The journal of cell biology/The Journal of cell biology” A new protein was made to detect specific skin cell growth receptors and worked in normal skin but not in skin cancer cells.
64 citations,
March 2005 in “Journal of Investigative Dermatology” Brain-Derived Neurotrophic Factor (BDNF) slows down hair growth and promotes hair follicle regression.
49 citations,
July 2009 in “Fitoterapia” Essential oils from Chamaecyparis obtusa may help hair grow by increasing a growth-related gene.
16 citations,
February 2007 in “Plastic and Reconstructive Surgery” Keratinocytes show more TGF-β system activity and collagen production as they age, which might affect wound scarring.
November 2023 in “PubMed” Naringenin and its combination with minoxidil significantly improved hair growth in mice.
2 citations,
January 2019 in “Annals of Dermatology” Melandrium firmum extract helps mice grow hair by blocking a hair loss enzyme and changing hair growth genes.
2 citations,
January 2002 in “The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology” Sophora flavescens extract helps hair grow and prevents acne.
January 2022 in “Clinical Cases in Dermatology” Some hair loss from medication may reverse after stopping the drug, but treatment options are limited and ongoing research is needed.
Tomato extract can promote hair growth and prevent hair loss without irritating the skin.
10 citations,
May 2012 in “Cell Adhesion & Migration” ILK and ELMO2 help cells move and stick together, important for wound healing and hair growth.
October 2018 in “InTech eBooks” The gene Foxn1 is important for hair growth, and understanding it may lead to new alopecia treatments.
92 citations,
September 2019 in “ACS nano” A wearable device using electric stimulation can significantly improve hair growth.
32 citations,
June 2015 in “PLOS ONE” Olive leaf compound oleuropein helps grow hair in mice.
2 citations,
January 2009 A natural extract-based hair growth product was developed and showed promise in preliminary tests.
January 2016 in “대한미용학회지” Lavender oil promotes hair growth in mice.
1 citations,
August 2016 in “Hanbang an'i'bi'in'hu pibu'gwa haghoeji” YangHyulEum Gami-Bang extract may help treat hair loss.
Integrin alphavbeta6 is important for wound healing and hair growth, and blocking it may improve these processes.
99 citations,
September 2007 in “The American journal of pathology” Chemotherapy damages hair follicles, causing hair loss and other cellular changes.
75 citations,
October 2002 in “Journal of Dermatological Science” Sophora flavescens extract may help hair grow by affecting growth factors and blocking a hair-related enzyme.
19 citations,
November 2001 in “Journal of Investigative Dermatology Symposium Proceedings” Human hair follicles can regenerate and recover after severe injury by going through a brief abnormal resting phase before growing again.